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All Journal Miracle Journal Of Public Health (MJPH)
Febriansyah, Rafa Ilham
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Health Professions Public Health

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Salted Fish Consumption Factors on the Incidence of Nasopharyngeal Cancer: A Systematic Review Syafira, Seftiani; Siregar, Salwa Febriana Ekasari; Saputra, Diki; Febriansyah, Rafa Ilham; Ariyanto, Januar
Miracle Journal of Public Health Vol 8 No 1 (2025): Miracle Journal of Public Health (MJPH)
Publisher : Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36566/mjph.v8i1.411

Abstract

Nasopharyngeal cancer (NPC) is a squamous cell cancer that originates from the epithelial lining of the nasopharynx. The issue of salted fish consumption is a concern because the salt preservation process can produce carcinogenic nitrosamine compounds. The nitrosamine content is formed from the reaction between nitrite, nitrate, and secondary amines, which has the potential to cause cell changes to become malignant if consumed in the long term, especially from an early age. This study aimed to systematically review the consumption pattern of salted fish based on age, frequency of consumption, and its potential risk of NPC and to identify gaps in the results of previous studies. The method used was a systematic review by searching the literature on online databases such as Scopus, PubMed, ScienceDirect, and Garuda. A total of 126 articles were obtained, and 11 articles met the criteria. The results of the analysis showed that there are differences in salted fish consumption patterns based on age and frequency that may increase the risk of NPC, especially in individuals who started consuming in childhood and high amounts. This study highlights the need for further research that considers genetic aspects, types of salted fish, and processing methods in different regions to clarify the causal relationship.
Co-Authors Ariyanto, Januar Saputra, Diki Siregar, Salwa Febriana Ekasari Syafira, Seftiani