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Pelatihan skrining tumbuh kembang bagi Guru PAUD di Kota Palembang Lestari, Hertanti Indah; Kesuma, Yudianita; Karmila, Ariesti; Ayu, Dewi Rosariah; Akbari, Atika
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 6 No 1 (2025): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V6I1.151

Abstract

Child development disorders can affect the next stage of growth and development and can have an impact on the future. Good and proper care for children who are in the growth and development period will help children to grow healthy and be able to achieve their optimal abilities so that they can contribute better to society. The main objectives of this community service are to improve the skills of Early Childhood Education (ECE) teachers to detect early growth and development disorders, reduce the number of advanced growth and development disorders, and optimize child growth and development with early intervention. The method of service carried out in this activity is in the form of training on the use of the PRIMAKU application for 1000 ECE teachers in Palembang City and assessed using pre-test and post-test questionnaires. The results of the counseling showed an increase in results in two benchmarks, an increase in participant knowledge based on the results of the pre-test and post-test correct answers by 17.03%. Furthermore, it is expected that PAUD teachers who have attended the training can apply the use of the PRIMAKU application for early detection of growth and development disorders or delays in early childhood.
Changes in Antibiotic Resistance Patterns Before and During the COVID-19 Pandemic in Hospitalized Children at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia Kitty, Winnie; Iriani, Yulia; Karmila, Ariesti
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.173-179

Abstract

Highlights: Antibiotic resistance patterns before and during COVID-19 have changed. There was an increase in MDR, MRSA, ESBL, and CRE isolates.   Abstract Introduction: The coronavirus disease (COVID-19) pandemic has influenced antibiotic usage patterns due to overlapping clinical symptoms between viral and bacterial infections. This may lead to inappropriate antibiotic prescriptions, thereby increasing antimicrobial resistance. This study examined antibiotic resistance patterns in hospitalized children before and during the COVID-19 pandemic, highlighting their clinical and epidemiological significance. Methods: This was a retrospective cross-sectional study using secondary data from the Central Laboratory Installation at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia. All patients aged 1 month to 18 years old with blood cultures and antibiotic sensitivity test results were included. The data were analyzed using Chi-square and linear regression in Microsoft Excel and the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 26.0 for Windows. Results: The proportion of Gram-positive bacterial isolates increased from 66% before the pandemic to 75% during the pandemic. The proportion of multidrug-resistant (MDR) isolates rose from 71.7% to 74.3%. Methicillin-resistant Staphylococcus aureus (MRSA) isolates rose from 20.6% to 25.8%. The proportion of extended-spectrum beta-lactamase (ESBL) isolates increased from 81.8% to 88.9%. All Enterobacteriaceae isolates were carbapenem-resistant Enterobacteriaceae (CRE). Significant resistance changes were observed in S. aureus to oxacillin. Conclusion: There was a change in antibiotic resistance patterns during the pandemic. These findings are crucial for antibiotic stewardship and clinical policy-making.
Epigenetik pada Alergi Susu Sapi Vera, Risa; Irfannuddin, Irfannuddin; Salim, Eddy Mart; Karmila, Ariesti
Sari Pediatri Vol 26, No 6 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.6.2025.399-404

Abstract

Alergi susu sapi dipengaruhi oleh dua faktor utama, yaitu predisposisi genetik dan faktor lingkungan. Interaksi antara faktor genetik dan faktor lingkungan mencetuskan terjadinya alergi susu sapi diperantarai oleh mekanisme epigenetik. Faktor lingkungan selama masa prenatal  maupun postnatal dapat memengaruhi program epigenetik pada masa awal perkembangan sistem imun. Faktor lingkungan, seperti paparan terhadap mikroba, faktor diet pada  ibu dan anak serta  mikrobiota pada saluran cerna memengaruhi  proses imunitas di masa yang akan datang dan berperan penting dalam perkembangan penyakit alergi.