Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Klinikal Sains (Jurnal Analis Kesehatan) IPSSJ
Hengky Ardian
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Public Health Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
EFEK CURCUMA LONGA (KUNYIT) TERHADAP PERUBAHAN HISTOPATOLOGI PADA KARSINOMA KOLOREKTAL: SYSTEMATIC LITERATURE REVIEW Hengky Ardian; Eva Roswati
Integrative Perspectives of Social and Science Journal Vol. 2 No. 03 Agustus (2025): Integrative Perspectives of Social and Science Journal
Publisher : PT Wahana Global Education

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Karsinoma kolorektal (KKR) merupakan salah satu penyebab utama mortalitas kanker global. Curcuma longa (kunyit) dan kurkumin memiliki aktivitas anti-inflamasi, antioksidan, dan antikanker, termasuk pengaruh pada perubahan histopatologi tumor. Menilai secara sistematis bukti ilmiah mengenai efek Curcuma longa terhadap perubahan histopatologi pada karsinoma kolorektal. Review ini dilakukan sesuai PRISMA 2020. Pencarian dilakukan pada PubMed, Embase, Scopus, Web of Science, Cochrane, ClinicalTrials.gov, dan Garuda/SINTA hingga Agustus 2025. Artikel inklusi: studi klinis, in vivo, dan in vitro yang mengevaluasi efek kunyit/kurkumin terhadap parameter histopatologi/biomarker jaringan pada kanker kolorektal. Dari 1.243 artikel yang teridentifikasi, 27 memenuhi kriteria. Kurkumin dilaporkan menurunkan indeks proliferasi (Ki-67), meningkatkan apoptosis (TUNEL, caspase-3), serta memperbaiki morfologi histopatologi pada model hewan maupun kultur sel. Beberapa uji klinis menunjukkan manfaat sebagai terapi adjuvan, meskipun hasil masih heterogen. Curcuma longa berpotensi sebagai agen adjuvan untuk kanker kolorektal melalui modifikasi perubahan histopatologi dan biomarker jaringan. Namun, uji klinis berskala besar masih dibutuhkan untuk konfirmasi.
ANALISIS KADAR ASAM LAKTAT DENGAN INTENSITAS LOW BACK PAIN PADA PEMANEN SAWIT PT X KABUPATEN KAMPAR yuharika pratiwi; Hengky Ardian; Nova Melinda
Klinikal Sains : Jurnal Analis Kesehatan Vol. 12 No. 2 (2024): Desember
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v12i2.5346

Abstract

Background: Repetitive movements and poor body posture during work often cause low back pain (LBP), which radiates pain from the corner of the lowest ribs to the corner of the buttocks in the lumbar-sacral area. The prevalence of LBP ranges between 60 - 80% in the world. Risk factors for LBP in workers are excessive workload on the bones, which causes injury or trauma to soft tissue. Palm harvesters often experience muscle tension due to awkward postures for long periods, resulting in increased lactic acid levels, which are related to the intensity of LBP. An initial survey of PT Objective: To determine the analysis of the relationship between lactic acid levels and low back pain in palm oil harvesters at PT. X Kampar Regency Method: This research is an observational analytic, cross-sectional design. The sampling technique uses total sampling, with statistical tests using the Spearman test. Results: The results of the Spearman correlation test showed that p-value = 0.000; r 0.649 with a strong positive relationship strength. Conclusion: There is a relationship between lactic acid levels and LBP intensity in PT palm oil harvesters. X.
Co-Authors Eva Roswati Nova Melinda Pratiwi, Yuharika