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KORELASI ANTARA NILAI HBA1C DAN KADAR KOLESTEROL LDL PADA PENDERITA DIABETES MELITUS TIPE 2 DI RSUD WALED KABUPATEN CIREBON Ahyaeni, Fenni Nurian; Luthfi, Muhammad; Brajadenta, Gara Samara; Noviani, Isti; Loebis, Irwan Meidi; Emman, Irene Max
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 11 No 1 (2025): TUNAS MEDIKA JURNAL KEDOKTERAN & KESEHATAN
Publisher : Fakultas Kedokteran UGJ Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33603/tumed.v11i1.10298

Abstract

Latar Belakang: Diabetes Melitus (DM) Tipe 2 merupakan penyakit gangguan metabolik yang ditandai dengan kenaikan gula darah. Diagnosis DM dapat dilakukan dengan pemeriksaan kadar glukosa darah secara enzimatik dengan HbA1c. Low density lipoprotein (LDL) merupakan jenis kolesterol berbahaya dan paling banyak terdapat di dalam darah. Peningkatan kadar kolesterol LDL menjadi penyebab utama terjadinya gangguan yang menimbulkan penyakit jantuk koroner (PJK). Pasien DM dengan PJK dikarenakan adanya peningkatan kadar kolesterol LDL. Tujuan: Penelitian ini dilakukan untuk mengetahui korelasi antara nilai HbA1C dan kadar kolesterol LDL pada penderita DM tipe 2. Metode: Penelitian ini menggunakan metode cross sectional dengan sampel 53 responden. Peneliti menggunakan data sekunder dengan analisa univariat dan bivariat. Hasil: Peneliti mendapatkan nilai HbA1C rata-rata penderita DM tipe 2 adalah 20,93% dan hasil nilai LDL tertinggi adalah 255,90 mg/dl. Hasil perhitungan analisa didapatkan HbA1C >6,5 bermakna dengan nilai p = 0,000 <0,050 yang berarti terdapat hubungan yang bermakna antara HbA1C dan kadar kolesterol LDL dengan penderita DM tipe 2. Simpulan: Hasil analisis dalam penelitian tersebut membuktikan adanya korelasi positif antara nilai HbA1C dan kolesterol LDL pada penderita Diabetes Melitus tipe 2. Kata kunci: Low density lipoprotein (LDL), kolesterol, diabetes melitus ABSTRACT Background: Diabetes Mellitus (DM) Type 2 is a metabolic disorder disease characterized by an increase in blood sugar. The diagnosis of DM can be made by examining blood glucose levels enzymatically with HbA1c. Low density lipoprotein (LDL) is a dangerous type of cholesterol and is the most abundant in the blood. Increased levels of LDL cholesterol are the main cause of disorders that cause coronary heart disease (CHD). DM patients with CHD due to an increase in LDL cholesterol levels. Aim: This study was conducted to determine the correlation between HbA1C values ​​and LDL cholesterol levels in patients with type 2 diabetes. Methods: This study used a cross sectional method with a sample of 53 respondents. Researchers used secondary data with univariate and bivariate analysis. Results: Researchers found the average HbA1C value for patients with type 2 diabetes was 20.93% and the highest LDL value was 255.90 mg/dl. In the calculation results, it was found that HbA1C > 6.5 was significant with p value = 0.000<0.050, which means that there was a significant relationship between HbA1C and LDL cholesterol levels with type 2 DM patients. LDL cholesterol in patients with type 2 diabetes mellitus. Conclusion: From the results of the analysis in this study, it was proven that there was a positive relationship between HbA1C and LDL cholesterol levels with type 2 DM patients
KARAKTERISTIK GAMBARAN PATOLOGIS VERTEBRAE LUMBOSACRAL PADA PEKERJA TAMBANG USIA 20 – 45 TAHUN DENGAN KELUHAN LOW BACK PAIN Nugraha, Verrel Adventa; Emman, Irene Max; Dewangga, Taufan Herwindo; Royyani, Nunik; Kusnandang, Agus
Tunas Medika Jurnal Kedokteran & Kesehatan Vol 10 No 3 (2024): TUNAS MEDIKA JURNAL KEDOKTERAN & KESEHATAN
Publisher : Fakultas Kedokteran UGJ Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33603/tumed.v10i3.9586

Abstract

ABSTRAKPekerja tambang saat ini banyak berusia muda tetapi mengeluhkan low back pain dan setelah dilakukan screeningdengan foto rontgen terdapat gambaran penyempitan diskus intervertebralis, sklerotik end plate, osteofit,spondylolithesis, dan stenosis foramen intervertebralis. Dampak yang dialami oleh pekerja tambang tersebut dapatdikarenakan beban kerja yang berat dan lama kerja, usia, obesitas, dan kurang berolahraga. Ilmu yang mempelajaritentang rontgen vertebrae dan pertulangan yang berkaitan dengan pekerjaan disebut radiologi dan orthopedi.Untuk mengetahui karakteristik gambaran patologis radiografi pada vertebrae lumbosacral terhadap usia,pekerjaan, jenis kelamin dengan keluhan low back pain (LBP) pada pekerja tambang usia 20 – 45 tahun. Penelitianobservasional ini menggunakan rancangan deskriptif retrospektif. Sampel diambil dari hasil foto rontgen sebanyak54 orang. Teknik pengambilan sampel menggunakan Total sampling. Analisis data untuk melihat karakteristikgambaran patologis radiografi vertebrae lumbosacral pada pasien dengan pekerjaan sebagai pekerja tambang.Berdasarkan uji univariat didapatkan usia dewasa awal 26 – 35 tahun sebanyak 32 (59,3%), remaja akhir 20 – 25tahun sebanyak 13 (24,1%), dewasa akhir 36 – 45 sebanyak 9 (16,7%), laki - laki sebanyak 49 (90,7%), perempuansebanyak 5 (9,3%), penyempitan diskus intervertebralis sebanyak 50 (87,7%), osteofit sebanyak 7 (12,3%),sklerotik end plate sebanyak 0 (0%), spondylolithesis sebanyak 0 (0%), stenosis foramen intervertebralis sebanyak0 (0%). Karakteristik gambaran patologis radiografi vertebrae lumbosacral pada pasien pekerja tambangberdasarkan usia paling banyak di dapat adalah pasien usia dewasa awal, untuk jenis kelamin paling banyak adalahlaki - laki, untuk hasil foto rontgen paling banyak di dapat adalah penyempitan diskus intervertebralis.Kata kunci : Temuan radiologis lumbal, rontgen lumbal pekerja tambang, rontgen pasien LBP, rontgen lumbalpasien usia mudaABSTRACTToday's mining workers are mostly young but complain of low back pain and after screening with X-rays thereare pictures of narrowing of the intervertebral discs, sclerotic end plates, osteophytes, spondylolithesis, andstenosis of the intervertebral foramen. The impact experienced by mining workers can be due to heavy workloadand length of work, age, obesity, and lack of exercise. The science that studies X-rays of the vertebrae and bonesrelated to work is called radiology and orthopedics. To find out the characteristics of radiographic pathology ofthe lumbosacral vertebrae on age, occupation, gender with complaints of low back pain (LBP) in miners aged 20-45 years. This observational study used a retrospective descriptive design. Samples were taken from the results ofX-rays as many as 54 people. The sampling technique used total sampling. Data analysis to see the characteristicsof the pathological picture of lumbosacral vertebrae radiography in patients with occupations as mining workers.Based on univariate tests, it was found that the age of early adulthood 26 - 35 years was 32 (59.3%), lateadolescence 20 - 25 years was 13 (24.1%), late adulthood 36 - 45 was 9 (16.7%), men were 49 (90.7%), femaleas many as 5 (9.3%), intervertebral disc narrowing as many as 50 (87.7%), osteophytes as many as 7 (12.3%),sclerotic end plate as many as 0 (0%), spondylolithesis as many as 0 (0%), intervertebral foramen stenosis asmany as 0 (0%). The characteristics of the radiographic pathological picture of lumbosacral vertebrae in mineworker patients based on age are mostly early adult patients, for the most gender is male, for the most X-rayresults are narrowing of the intervertebral disc.Keywords : lumbar radiologic findings, lumbar x-rays of mine workers, X-ray of LBP patient, lumbar x-ray of ayoung patient