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All Journal Jurnal Fisika Unand Makara Journal of Science
Aimon, Akfiny Hasdi
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Earth & Planetary Sciences Electrical & Electronics Engineering Energy Materials Science & Nanotechnology Physics

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Porous Calcium Carbonate-Poly-2-Acrylamido-2-Methylpropanesulfonic Acid Microspheres Embedded with Silver-Based Nanoparticles as Potential Antibacterial Carriers for Bone Infections Rini, Novi Dwi Widya; Asmoro, Adinda; Rachmawati, Systi Adi; Ardy, Husaini; Aimon, Akfiny Hasdi; Kishimura, Akihiro; Katayama, Yoshiki; wibowo, arie
Makara Journal of Science Vol. 29, No. 2
Publisher : UI Scholars Hub

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Abstract

Implant-associated infections (IAIs) are a significant complication following orthopedic surgeries and are mainly caused by Staphylococcus aureus. In this study, microspheres based on hybrid calcium carbonate–poly-2-acrylamido-2-methylpropane sulfonic acid (CaCO3-PAMPS) embedded with silver-based nanoparticles (AgNPs) were developed as potential antibacterial drug carriers for IAIs. AgNPs were prepared via a green synthesis approach, which employed Indonesian wild honey as a reducing and capping agent. PAMPS concentrations (0.025%, 0.050%, and 0.075% w/v) and silver ion (Ag+) concentrations in solution (0%, 2.5%, and 4% w/v) were varied. Scanning electron microscopy images showed that samples with 0.050% w/v PAMPS and 2.5% w/v Ag+ exhibited remarkable stability against recrystallization and aggregation. The sample exhibited more homogeneous, free-standing vaterite particles. Moreover, the particles obtained displayed a porous structure, promising for loading active ingredients. In addition, the X-ray diffraction results confirmed that the Ag-based particles embedded were not only AgNPs but were also predominantly composed of AgCl. AgNPs and AgCl in this sample demonstrated antibacterial activity against Staphylococcus aureus (zone of inhibition of 7.2 ± 0.6 mm). The development of stable, homogeneous microspheres with antibacterial properties and drug-loading potential offers a promising solution for the prevention and treatment of IAIs, addressing a critical challenge in orthopedic surgery.
Pengembangan Prototipe Alat Pengukur Medan Magnet Menggunakan Sensor Magnetik 49E Nur, Rechan Zahrotun; Aminah, Nina Siti; Aimon, Akfiny Hasdi
Jurnal Fisika Unand Vol 13 No 4 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jfu.13.4.573-578.2024

Abstract

The magnetic field is an interesting physical phenomenon and found in everyday life. Many currents technological developments are applications of the magnetic field concept, such as electronics, electric motors, fast trains, and others. In this research, a prototype for measuring magnetic fields was developed with a physics instrumentation system. This prototype can be used for experimental measurements of magnetic fields for physics lecture in the school. It was found that a magnetic field measurement tool could be made using a physics instrumentation system. So, this tool can be used as an experimental medium for measuring the magnitude of the magnetic field in permanent magnet and wires carrying electric current. The prototype was consisted a 49E magnetic sensor. It is hoped that the prototype can replace the Gaussmeter or Teslameter which are relatively expensive. The prototype magnetic field measuring instrument was calibrated by comparing the magnetic field strength measured by the 49E sensor with the Lutron GU-3001 Gaussmeter. Measurements are observed at the centre of the object and parallel to the position of the measuring instrument. The results of the measurements show that the average magnetic field strength on the Gaussmeter and 49E sensor is 246.7 μT and 487.3 μT for permanent magnet and 51.2 μT and 96.9 μT for coiled wires.
Co-Authors Aminah, Nina Siti Ardy, Husaini Arie Wibowo Asmoro, Adinda Katayama, Yoshiki Kishimura, Akihiro Nur, Rechan Zahrotun Rachmawati, Systi Adi Rini, Novi Dwi Widya