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All Journal JURNAL FARMASIMED (JFM) Jurnal Pengmas Kestra (JPK)
Syahfitri, Wilda Dani
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Health Professions Medicine & Pharmacology Nursing Public Health

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Testing The Effectiveness of An Ethanol Extract Gel Preparation of Kelakai Leaves (Stenochlaena palustris (Burm.F.) Bedd.) on Reducing The Extent of Burns in Male White Rats (Rattus novergicus) Syarifuddin, Aminah; Novandi Purba; Yayuk Rahayu Suyudi; Elliya Siswanti; Syahfitri, Wilda Dani
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2685

Abstract

The wound healing process is essential for restoring body tissue to its original integrity or normal function. This process involves several stages, including the inflammatory, proliferative, and maturation phases. Both internal and external factors play a role in accelerating wound healing. Kelakai leaves are traditionally used as a topical treatment for burns in gel form, as they are safe for use, non-toxic, and do not cause harmful side effects. The most significant effect was observed with the gel formulation containing 15% w/w kelakai leaf extract, which was able to reduce burn wound area by 13.75%. This demonstrates the effectiveness of kelakai leaf extract gel (Stenochlaena palustris (Burm. F.) Bedd.) in the wound healing process. Therefore, the gel has the potential to reduce the extent of burn injuries.The aim of this study was to analyze the effect of various concentrations of ethanol-based kelakai leaf extract gel. As an effort to reduce burn wound area, this research included several stages, starting from the collection of materials and equipment, plant identification, research procedures, to the extraction process of kelakai leaf simplicia using maceration. This was followed by phytochemical screening and gel formulation at concentrations of 5%, 10%, and 15%, which were then tested for effectiveness on male white rats. The data were analyzed using ANOVA with a significance level of p < 0.050. The findings indicate that the gel containing kelakai leaf extract has a significant effect in reducing the burn wound area in rats.
Education on the Benefits of Ethanol Extract Gel Preparation from Kelakai Leaves as a Burn Wound Treatment in Pantai Labu District Syarifuddin, Aminah; Syahfitri, Wilda Dani; Suyudi, Yayuk Rahayu
JURNAL PENGMAS KESTRA (JPK) Vol. 5 No. 1 (2025): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/cmqwqn65

Abstract

Skin care is essential to protect the skin from damage, which can be achieved through healthy dietary intake and the direct application of topical products. The wound healing process plays a vital role in restoring tissue integrity and normal function. This process occurs in several phases, namely inflammation, proliferation, and maturation. The leaves of the kelakai plant have been utilized as the active ingredient in topical gel formulations due to their perceived safety and effectiveness. A gel formulation with a 15% w/w concentration has been proven to be the most effective, capable of reducing burn wound area by up to 13.75%, particularly in severe burn cases. These findings indicate the strong potential of kelakai leaf extract gel as an alternative treatment for burn injuries. A community service activity (PkM) involving 97 residents of Pantai Labu District was conducted with the aim of increasing public awareness regarding the proper and safe selection of topical medications. Participants were educated on the benefits, safety, and stability of the kelakai leaf extract gel, including the importance of appropriate pH levels that are compatible with human skin. Post-activity assessments revealed an increase in participants’ knowledge by 50% and 30% based on pre-test and post-test results, respectively, indicating the success of the program in enhancing understanding of plant-based topical gels as an alternative burn treatment. The PkM team also encouraged participants to be more selective and cautious when using similar products. This educational initiative successfully improved public knowledge regarding the use of medicinal plants as herbal remedies for burn wounds.
Co-Authors Elliya Siswanti Novandi Purba Suyudi, Yayuk Rahayu Syarifuddin, Aminah Yayuk Rahayu Suyudi