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Socialization of The Use of Melinjo Leaf Ethanol Extract (Gnetum gnemon L.) on Growth Salmonella typhi Bacteria Syarifuddin, Aminah; Pranata, Chandra; Boru Situmorang, Novidawati; Octora, Debi Dinha; Ramadhani, Lili
JURNAL PENGMAS KESTRA (JPK) Vol. 3 No. 1 (2023): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v3i1.1149

Gnetum gnemon L. has antibacterial activity against Salmonella typhi because it contains flavonoids, saponins, tannins, alkaloids, and steroids. Where these compounds play an important role as an antibacterial. The purpose of this service is to provide information to the public regarding the benefits of melinjo leaves which can act as an antibacterial agent. This service activity is carried out in the form of socialization using lecture, question and answer, and demonstration methods. The number of participants in this community service activity was 20 pharmacists at Grandmed Lubuk Pakam Hospital. Based on the results of the PkM activities carried out, it can be stated that there has been an increase in public knowledge regarding the efficacy of melinjo leaves as an antibacterial substance. This can be proven by the increase in post-test scores when compared to pre-test scores. The average increase in the knowledge of PkM participants was 21.5. On the other hand, the highest post-test score obtained was 85, while the lowest post-test score was 60. Meanwhile, based on the PkM material that had been socialized, the PkM participants understood that the results of phytochemical tests on melinjo leaf Simplicia showed that melinjo leaf extract contains compounds alkaloids, flavonoids, steroids, saponins, and tannins. Meanwhile, the antibacterial test showed that the inhibition zones of various concentrations included a moderate concentration of 40%, a moderate category of 60%, and a strong category of 80%. The average diameter of the inhibition zone increased with each concentration of melinjo leaves.

Focus Group Discussion on The Rationality of Using Gastritis Drugs in Patients Suffering from Osteoarthritis at The Batang Kuis Health Center Syarifuddin, Aminah
JURNAL PENGMAS KESTRA (JPK) Vol. 3 No. 2 (2023): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v3i2.1977

In developing countries, chronic gastritis is the most common type of gastritis with In various countries currently, chronic gastritis occupies a position as a frequently encountered gastritis disease, where the prevalence depends on geographic and socio-economic conditions. Gastritis is a type of disease that causes inflammation of the stomach mucosa. If you take osteoarthritis medicines such as NSAIDS without instructions for use, it will trigger gastrointestinal disease. Gastritis is one of the types of disease with the highest incidence rate. Age and gender factors are generally very susceptible to gastritis. Osteoarthritis (OA) is a type of arthritis that has chronic impacts and causes many public health problems. Osteoarthritis presents with many different symptoms. The aim of this PkM activity is to educate PkM participants in understanding the gastritis drug regimen that should be recommended to osteoarthritis patients and the rationale for treatment. Seminar activities are carried out using lecture and Focus Group Discussion (FGD) methods. The PkM participants were patients at the Batang Kuis Community Health Center, totaling 50 patients who were determined randomly. There were 30 male patients and 20 female patients. The questionnaire was chosen as a measuring tool to measure the success of this PkM activity. The PkM results showed that 90% or 45 PkM participants stated they were very satisfied with the rationality of using gastritis medication and there were 10% or 5 PkM participants who stated they were satisfied.

Education on The Danger of Hydroquinone in Whitening Body Lotion Products in The Community Sinurat, Jhon Patar; Br Karo, Reh Malem; Husna, Miftahul; Syarifuddin, Aminah
JURNAL PENGMAS KESTRA (JPK) Vol. 4 No. 1 (2024): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v4i1.2203

White and bright skin is considered a symbol of beauty, success, and social status, especially in several Asian countries. This is the basis for feeling the need to care for skin, especially women. One way to care for your skin is by using whitening body lotion products so that it will produce an attractive appearance, where white and bright skin is the indicator. Finally, many women compete to use instant whitening products at low prices, but forget about the impact. Hydroquinone is an organic compound with an aromatic group that is usually added to some skin-whitening products. However, you need to pay attention to the levels and duration of use, because it can cause skin irritation and trigger cancer because it is a carcinogen. The hydroquinone level in the product is a maximum of 0.02%. This educational activity is carried out by combining methods, namely lectures, questions and answers, and discussions. PkM participants are 25 people from Lubuk Pakam. The PkM team also carried out pre and post-test activities to measure the level of knowledge of PkM participants after being given education. The PkM results provide new insight for PkM participants that some whitening products contain hydroquinone compounds at levels that exceed the limit, so PkM participants must know about the dangers of hydroquinone and how to choose safe whitening products. After being given education, PkM participants have experienced an increase in knowledge where the participants' post-test average score was 80,2 whereas the previous pre-test average score was 55,7.

EFEKTIFITAS EKSTRAK ETANOL DAUN SAWI HIJAU (BRASSICA RAPA VAR. PARACHINENSIS) SEBAGAI PELEMBAB KULIT DENGAN SEDIAAN MASKER PEEL-OFF Cahya, Cucu Arum Dwi; Syarifuddin, Aminah; Syukur, Ahmad Syukur
Jurnal FARMASIMED (JFM) Vol 2 No 1 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Green mustard plants can be formulater into peel-off masks to moisturize the skin, because based on previous research green mustard leaves cointain flavonoids as antioxidants which can moisturize the skin. The purpose of this study was to find out green mustard leaves can be formulated into peel-off mask preparations and to find out the preparation and to find out the preparation off peel off mask with etanol extract of green mustard leaves can moisturize the skin. This study uses an experimental method. Green mustard leaves are extracted by maceration. In this study, a skin analyzer was usee as a mesure of skin moisture level after using peel off mask from a variety of dosage formulations which were divided into 5 preparations, blank (without mask, 3%,4%,5%), postive control (using peel off masks on the market). The Anova test results show a sig value of 0,000 or p<0,005 so it is concluded that the variabel has a difference. The conclusion of this study proves that the ethanol extract of green mustard leaves can be used as a peel-off mask for skin moisturizer, where the higher the concentration of mustard leaf extract, the higher the moisture vlue of the skin.

THE EFFECT OF ETHANOL EXTRACT OF SOURSOP LEAVES (ANNONA MURICATA L.) ON BODY TEMPERATURE IN MALE MICE (MUS MUSCULUS) INFECTED WITH BACTERIA SALMONELLA TYPHI Syarifuddin, Aminah; Cahya, Cucu Arum Dwi; Br Sihombing, Amelya Chyntia
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1929

Soursop leaves (Annona muricata L.) are a plant that has many health benefits that can be obtained from the fruit, leaves, and seeds. Soursop leaves contain saponins, flavonoids, tannins, and alkaloids which can act as an antiseptic-disinfectant or as an antibacterial. Flavonoid compounds can be used as wound medicine, antifungal, antimicrobial, anticancer, and antiviral. In society, it is used by boiling the leaves and then drinking the boiled water. This research aims to determine the effectiveness of soursop leaf ethanol extract as an antibacterial against Salmonella typhi so that fever can be reduced. The dosage includes 100; 150; 200; and 250 mg/kg BW. No treatment was given as a negative control and chloramphenicol tablets as a positive control. Based on data analysis, it shows that there is a significant difference in body temperature after being tested using the t-test with a value of 0.000 < 0.05. These results prove that body temperature which was initially normal during the acclimatization stage experienced an increase in body temperature when infected with Salmonella typhi. The results of the One-Way ANOVA test also showed an effect on reducing body temperature infected with Salmonella typhi. From several doses, the EDDS dose of 100 mg/kg BW was able to reduce body temperature by an average of 36.5°C.

Lotion Formulation with Papaya Seed Extract (Carica Papaya L) as a Skin Moisturizer Syarifuddin, Aminah; Juliana, Iga
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2342

Papaya seeds (Carica papaya L) have many vitamin contents that function to help increase immunity, fight free radicals, and also help increase skin moisture. Lotion is one of the pharmaceutical preparations in the form of beauty products that function to brighten and help increase skin moisture. In this research, a formulation of papaya seed extract will be made to become a lotion preparation that can increase skin moisture. This study tested the effectiveness of the preparation on the skin of volunteers. This study was conducted by making papaya seed extract through a maceration process using 96% ethanol, the extract was formulated in a lotion preparation in various concentrations. The resulting lotion was tested for homogeneity, pH, organoleptic, moisture and irritation on volunteers. Treatment was carried out for three days using lotion once a day. Lotion with a concentration of 3%, 5% and 7% which was homogeneous with a blank pH of 5.64, a 3% formulation pH of 5.84, a 5% formulation pH of 5.72, and a 7% formulation pH of 5.95 was found to not irritate the skin of volunteers, stable in room temperature storage. The results of the humidity test on Blanko were 43.3%, 3% formulation 45.2%, 5% formulation 49.95, 7% formulation 52.45%, and comparator 41%. The best result of the humidity test was formulation 3 with a concentration of 7% with an average value of 52.45%. Papaya seed extract can be formulated as a lotion preparation because it meets the physical test requirements of the preparation which shows that the preparation is homogeneous, the pH is stable during storage at room temperature, and does not irritate the skin. The papaya seed extract lotion preparation with a concentration of 7% provides a better humidity level effect compared to Blanko, F1 (3%), F2 (5%), F3 (7%) and also the comparator preparation.

Utilization of Papaya Seed Extract Lotion as a Skin Moisturizer Syarifuddin, Aminah; Juliana, Iga; Sihombing, Yanna Rotua; Anggraeni, Ratih
JURNAL PENGMAS KESTRA (JPK) Vol. 4 No. 2 (2024): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jpk.v4i2.2430

The skin plays a role in protecting bones and muscles, which are generally soft and elastic. In order for the skin to be well protected, internal and external care is needed. Internal skin care is obtained by consuming healthy foods. While external skin care is through the use of preparations directly on the skin. Several types of skin damage occur due to exposure to free radicals, such as exposure to UV rays. To avoid these dangers, a lotion that can act as an antioxidant is needed. Papaya seeds are rich in antioxidants that can increase skin moisture so that they are recommended as a basic ingredient for making lotion. The purpose of this socialization is to educate the public to be more concerned about health by using the right skin moisturizing lotion. PKM activities were carried out through socialization attended by 50 people around the Pantai Labu sub-district. The socialization material presented was about the use of papaya seed extract lotion as a skin moisturizer. The team also taught participants to be more careful in choosing cosmetics before using them. Increased knowledge was measured based on the pre-test and post-test values ??obtained from all participants. The results showed that there had been an increase in the knowledge of PkM participants, where the level of knowledge became high and very high with a percentage of 50% and 30%. Increased knowledge in the form of understanding about the preparation of papaya seed extract lotion that is stable and has a distinctive aroma. The lotion is also safe for the skin because the acidity level is appropriate and does not irritate the skin. This PkM activity has proven to have increased the understanding of PkM participants that lotions made from plant extracts are actually worthy of being used as an alternative for skin care.

Analysis of Hydroquinone Compounds in Whitening Body Lotion Preparations Circulating in The Community Sinurat, Jhon Patar; Husna, Miftahul; Br Karo, Reh Malem; Syarifuddin, Aminah
JURNAL KESMAS DAN GIZI (JKG) Vol. 6 No. 2 (2024): Jurnal Kesmas dan Gizi (JKG)
Publisher : Fakultas Kesehatan Masyarakat Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkg.v6i2.2123

Skin care has become an important part for today's women. Whitening body lotion is very necessary in maintaining skin when doing activities outside and indoors. Many Indonesian women desire to have white, clean and bright skin so they can appear attractive. An attractive appearance is very necessary in society. To achieve this, many women choose skin care products at affordable prices without paying attention to the dangers of the chemical content in them. One of the skin whitening ingredients that is often used in beauty products is the compound hydroquinone. The hydroquinone compound plays a role in preventing skin pigmentation. However, if the levels exceed 0.02% in the preparation, it will cause skin irritation, kidney function disorders and cancer. The type of research is a mixed type, namely qualitative and quantitative. Qualitatively, it will obtain data on the presence of hydroquinone and quantitatively in the form of hydroquinone levels. The samples were 5 whitening body lotion preparations circulating in Lubuk Pakam which were determined randomly and were coded A, B, C, D, and E. Qualitative analysis was carried out using the TLC method and quantitative analysis was carried out using the UV-spectrophotometric method. Visible. The results of qualitative analysis show that samples A, C, and D contain hydroquinone compounds which are characterized by the appearance of blackish brown spots with respective Rf values of 0.89; 0.96; and 0.89. Meanwhile, when qualitative analysis was carried out, the levels obtained for the three samples were 44.56% each; 5,604%; and 5,612%. Based on regulations issued by BPOM RI in 2022, it is stated that hydroquinone levels in beauty products must not exceed 0.02%. So it can be concluded that whitening body lotion preparations with sample codes A, C, and D are not recommended for use because the use limit for hydroquinone is classified as unsafe. It is recommended that people, especially women, be more selective in choosing and using beauty products.

Testing The Effectiveness of An Ethanol Extract Gel Preparation of Kelakai Leaves (Stenochlaena palustris (Burm.F.) Bedd.) on Reducing The Extent of Burns in Male White Rats (Rattus novergicus) Syarifuddin, Aminah; Novandi Purba; Yayuk Rahayu Suyudi; Elliya Siswanti; Syahfitri, Wilda Dani
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2685

The wound healing process is essential for restoring body tissue to its original integrity or normal function. This process involves several stages, including the inflammatory, proliferative, and maturation phases. Both internal and external factors play a role in accelerating wound healing. Kelakai leaves are traditionally used as a topical treatment for burns in gel form, as they are safe for use, non-toxic, and do not cause harmful side effects. The most significant effect was observed with the gel formulation containing 15% w/w kelakai leaf extract, which was able to reduce burn wound area by 13.75%. This demonstrates the effectiveness of kelakai leaf extract gel (Stenochlaena palustris (Burm. F.) Bedd.) in the wound healing process. Therefore, the gel has the potential to reduce the extent of burn injuries.The aim of this study was to analyze the effect of various concentrations of ethanol-based kelakai leaf extract gel. As an effort to reduce burn wound area, this research included several stages, starting from the collection of materials and equipment, plant identification, research procedures, to the extraction process of kelakai leaf simplicia using maceration. This was followed by phytochemical screening and gel formulation at concentrations of 5%, 10%, and 15%, which were then tested for effectiveness on male white rats. The data were analyzed using ANOVA with a significance level of p < 0.050. The findings indicate that the gel containing kelakai leaf extract has a significant effect in reducing the burn wound area in rats.

Education on the Benefits of Ethanol Extract Gel Preparation from Kelakai Leaves as a Burn Wound Treatment in Pantai Labu District Syarifuddin, Aminah; Syahfitri, Wilda Dani; Suyudi, Yayuk Rahayu
JURNAL PENGMAS KESTRA (JPK) Vol. 5 No. 1 (2025): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/cmqwqn65

Skin care is essential to protect the skin from damage, which can be achieved through healthy dietary intake and the direct application of topical products. The wound healing process plays a vital role in restoring tissue integrity and normal function. This process occurs in several phases, namely inflammation, proliferation, and maturation. The leaves of the kelakai plant have been utilized as the active ingredient in topical gel formulations due to their perceived safety and effectiveness. A gel formulation with a 15% w/w concentration has been proven to be the most effective, capable of reducing burn wound area by up to 13.75%, particularly in severe burn cases. These findings indicate the strong potential of kelakai leaf extract gel as an alternative treatment for burn injuries. A community service activity (PkM) involving 97 residents of Pantai Labu District was conducted with the aim of increasing public awareness regarding the proper and safe selection of topical medications. Participants were educated on the benefits, safety, and stability of the kelakai leaf extract gel, including the importance of appropriate pH levels that are compatible with human skin. Post-activity assessments revealed an increase in participants’ knowledge by 50% and 30% based on pre-test and post-test results, respectively, indicating the success of the program in enhancing understanding of plant-based topical gels as an alternative burn treatment. The PkM team also encouraged participants to be more selective and cautious when using similar products. This educational initiative successfully improved public knowledge regarding the use of medicinal plants as herbal remedies for burn wounds.

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