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All Journal Formosa Journal of Science and Technology (FJST) International Journal of Health and Pharmaceutical (IJHP)
R. Bamahry, Aryanti
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Humanities Computer Science & IT Education Industrial & Manufacturing Engineering Nursing Public Health Social Sciences

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Comparison Of The Antibacterial Activity Of Palm Kernel Oil (PKO) & Virgin Coconut Oil (VCO) Against Pseudomonas Aeruginosa Bacteria Purnamasari, Juwita; Wahyuni Gayatri B, Sri; Sitti Fahirah Arsal, Andi; R. Bamahry, Aryanti; Karim, Marzelina
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 2 (2025): May 2025 ( Indonesia - Iraq - Malaysia)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i2.412

Abstract

Pseudomonas aeruginosa, a gram-negative bacterium, is a significant cause of nosocomial infections and exhibits high levels of multidrug resistance, necessitating the exploration of alternative antibacterial agents. This study investigates the antibacterial activity of Palm Kernel Oil (PKO) and Virgin Coconut Oil (VCO) against Pseudomonas aeruginosa, employing a true experimental post-test design with microdilution and agar dilution methods. Conducted at the Universitas Muslim Indonesia, the study determined the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of PKO, VCO, and gentamicin. Results revealed that PKO had an MIC of 4096 µg/mL and an MBC of 8192 µg/mL, while VCO exhibited an MIC of 2048 µg/mL and an MBC of 4096 µg/mL. Gentamicin, used as a control, demonstrated superior antibacterial effectiveness with an MIC of 2 µg/mL and an MBC of 4 µg/mL. Statistical analysis indicated that VCO, with its higher lauric and myristic acid content, was more effective than PKO in inhibiting bacterial growth, although both oils were less effective than gentamicin. The study highlights the potential of VCO as a natural antibacterial agent, suggesting further research to optimize its efficacy through formulation modifications and combinations with other antimicrobial agents. Additionally, evaluating the effectiveness of VCO and gentamicin against other bacterial strains is recommended to expand the understanding of VCO's antibacterial capabilities. These findings contribute to the growing body of evidence supporting the use of natural products in combating antibiotic-resistant infections.
The Effectiveness of Extra Virgin Olive Oil on Blood Pressure Reduction in Obese Women Indarwati Abdullah, Rezky Putri; Arifin Bando, Achmad Syafii; Wello, Eny Arlini Wello; R. Bamahry, Aryanti; Iskandar, Darariani
Formosa Journal of Science and Technology Vol. 3 No. 1 (2024): January 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v3i1.7768

Abstract

Extra virgin olive oil (EVOO), containing glycerol or subjected to hydrolysis, constitutes approximately 90-99% of the oil, primarily consisting of monounsaturated fatty acids (MUFA), with oleic acid comprising up to 80% of the total oil. This study aims to examine the influence of oleic acid in olive oil on reducing systolic blood pressure (SBP) and diastolic blood pressure (DBP). The intervention spanned 15 days, where the treatment group received EVOO, and the control group received a placebo (water), each administered twice a day at a dosage of 15 ml. Before the intervention, blood pressure was assessed with the Mann-Whitney test, while after intervention, measurements were analyzed using the Independent T-Test. Additional 15 ml Extra Virgin Olive Oil for 15 days results in significant decrease of systolic blood pressure and diastolic blood pressure compared to water only.
Co-Authors Arifin Bando, Achmad Syafii Indarwati Abdullah, Rezky Putri Iskandar, Darariani Juwita Purnamasari, Juwita Karim, Marzelina Sitti Fahirah Arsal, Andi Wahyuni Gayatri B, Sri Wello, Eny Arlini Wello