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Heart-type Fatty Acid-binding Protein (H-FABP) sebagai Diagnostik Awal dan Prognostik Infark Miokard Akut Ni Made Utami Wulandari; Putu Wika Pramesti Iswari; Yusra Pintaningrum
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2622

Abstract

Acute myocardial infarction (AMI) remains one of the leading causes of mortality and morbidity worldwide. Early diagnosis and accurate prognosis are vital to improve patient outcomes. Heart-type Fatty Acid-binding Protein (H-FABP) has emerged as a potential biomarker for AMI. H-FABP is a cytoplasmic protein encoded by the FABP3 gene, situated on chromosome 1 in the human genome. It plays a crucial role in active fatty acid metabolism and is implicated in the absorption, cellular metabolism, and/or transport of polyunsaturated fatty acids (PUFAs). During the pathogenesis of acute coronary syndrome (ACS), H-FABP is rapidly released into the circulation when myocardial ischemic injury occurs. Its early detection, around 1-2 hours after AMI, with a peak at 5-10 hours, and normalization within 24-36 hours, makes H-FABP an ideal candidate for early diagnostic and prognostic evaluation in AMI patients. Despite its excellent prognostic value, H-FABP's diagnostic sensitivity outweighs its specificity for AMI. This review discusses the potential of H-FABP as an early diagnostic and prognostic marker for AMI and emphasizes further studies and research are needed regarding the use of H-FABP as a diagnostic and/or prognostic marker for AMI.
Heart-type Fatty Acid-binding Protein (H-FABP) sebagai Diagnostik Awal dan Prognostik Infark Miokard Akut Ni Made Utami Wulandari; Putu Wika Pramesti Iswari; Yusra Pintaningrum
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2622

Abstract

Acute myocardial infarction (AMI) remains one of the leading causes of mortality and morbidity worldwide. Early diagnosis and accurate prognosis are vital to improve patient outcomes. Heart-type Fatty Acid-binding Protein (H-FABP) has emerged as a potential biomarker for AMI. H-FABP is a cytoplasmic protein encoded by the FABP3 gene, situated on chromosome 1 in the human genome. It plays a crucial role in active fatty acid metabolism and is implicated in the absorption, cellular metabolism, and/or transport of polyunsaturated fatty acids (PUFAs). During the pathogenesis of acute coronary syndrome (ACS), H-FABP is rapidly released into the circulation when myocardial ischemic injury occurs. Its early detection, around 1-2 hours after AMI, with a peak at 5-10 hours, and normalization within 24-36 hours, makes H-FABP an ideal candidate for early diagnostic and prognostic evaluation in AMI patients. Despite its excellent prognostic value, H-FABP's diagnostic sensitivity outweighs its specificity for AMI. This review discusses the potential of H-FABP as an early diagnostic and prognostic marker for AMI and emphasizes further studies and research are needed regarding the use of H-FABP as a diagnostic and/or prognostic marker for AMI.
Edukasi Kesehatan Pendengaran Akibat Penggunaan Headset atau Earphone di Poliklinik THT RSUD Praya Eka Arie Yuliyani; Ika Prasetyaningrum; Ni Made Utami Wulandari; M. Andre Darmawan
Jurnal Pengabdian Magister Pendidikan IPA Vol 9 No 2 (2026): April-Juni 2026
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v9i2.15667

Abstract

Ear and hearing health are often neglected, and sometimes people are unaware of hearing loss. Hearing loss can be caused by various factors and can affect all age groups. Noise is one factor that causes hearing loss. Improper use of headsets or headphones can cause hearing loss called Noise-Induced Hearing Loss (NIHL). Hearing loss in NIHL is a sensorineural type that generally affects both ears. This educational activity was conducted with the aim of providing information to the public about the importance of maintaining ear and hearing health and how to prevent it. Participants were very enthusiastic about participating in the activity and listening to every piece of information presented. The high level of enthusiasm from the participants can be used as a benchmark and evaluation of activities for better implementation in the future