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All Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Sosial dan Sains Enrichment: Journal of Multidisciplinary Research and Development
Napitupulu, Elfrida
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Humanities Astronomy Economics, Econometrics & Finance Engineering Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Physics Public Health Social Sciences

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Pengaruh Job Demands dan Job Resources terhadap Turnover Intention yang Dimediasi oleh Work Engagement pada PT. Misi Sehat Imani Tallo Adu, Yuliana; Napitupulu, Elfrida
Jurnal sosial dan sains Vol. 5 No. 4 (2025): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsosains.v5i4.32103

Abstract

Penelitian ini bertujuan untuk menganalisis pengaruh job demands dan job resources terhadap turnover intention dengan work engagement sebagai variabel mediasi di PT Misi Sehat Imani (Industri Retail). Meskipun industri retail memiliki potensi besar, tingginya turnover di PT Misi Sehat Imani menjadi hambatan utama yang disebabkan oleh budaya kerja dalam industri retail yang bertanggung jawab atas hal tersebut. Sampel penelitian dikumpulkan menggunakan teknik non-probability sampling dengan jumlah 250 responden karyawan PT Misi Sehat Imani. Analisis data dilakukan menggunakan PLS 4.0 dengan metode partial least square (PLS) dan structural equation model (SEM) untuk menguji hipotesis penelitian. Hasil penelitian menunjukkan bahwa semakin tinggi job demands, work engagement cenderung menurun dan turnover intention meningkat secara signifikan. Job demands di PT Misi Sehat Imani cenderung bersifat hindrance demand, yang ditunjukkan dengan melemahnya work engagement. Sebaliknya, semakin tinggi job resources, work engagement meningkat dan turnover intention menurun secara signifikan. Work engagement berperan memediasi parsial dalam hubungan antara job demands dan job resources terhadap turnover intention, karena job demands dan job resources memiliki pengaruh langsung terhadap turnover intention. Hasil penelitian menekankan pentingnya pengelolaan job demands dan job resources untuk meningkatkan retensi karyawan melalui peningkatan work engagement.
Profile of Dermatologic Side Effects of Tyrosine Kinase Inhibitor (EGFR-TKIs) in Lung Cancer Patients Napitupulu, Elfrida; Nurrochmad, Arief; Hanafi, Arif Riswahyudi; Wahyudi, Danang Tri
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 14, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.91322

Abstract

Background: Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKIs) drugs are commonly used target therapies in patients with advanced-stage non-small cell carcinoma lung cancer (NSCLC).Objectives: This study aims to provide an overview of dermatologic side effects and quality of life index of NSCLC patients who received EGFR-TKIs targeted therapy at Dharmais Cancer Hospital.Methods: This study used a cross-sectional design. Inclusion criteria were patients who received EGFR-TKIs targeted therapy, namely gefitinib, erlotinib, and afatinib, in September - October 2023, who were willing to be research subjects, and patients who were not in a medical emergency. In total, 52 patients filled out the dermatology life quality index (DLQI) questionnaire through interviews and medical records. Data evaluation was performed descriptively in the form of percentages.Results: The most common occurrence of dermatologic side effects was skin hypersensitivity reactions with mild severity (grade 1) by 59.6%, moderate severity (grade 2) by 19.2%, and severe severity (grade 3) by 1.9%, and no drug dermatologic side effects by 19.2%. In comparison, the most DLQI was in the category of not affecting patient life. In general, side effects with moderate (grade 2) and severe (grade 3). The severity will decrease to mild severity (grade 1) when already getting topical corticosteroid drugs or combinations with oral antibiotics and antihistamine drugs.Conclusion: The most severe side effect was grade 1, which slightly affected the patient's quality of life. Education and monitoring of side effects and management of symptoms are necessary to reduce the severity and improve patients' quality of life.
The Influence of Salesperson Competence and Sales Programs on Toyota's Sales Performance Moderated by The Leadership at Pt. Astra International, Tbk. – Tso harman, Harman; Napitupulu, Elfrida
Enrichment: Journal of Multidisciplinary Research and Development Vol. 2 No. 8 (2024): ENRICHMENT: Journal of Multidisciplinary Research and Development
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/enrichment.v2i8.185

Abstract

This study aims to analyze the influence of sales force competence and sales programs on Toyota sales performance, with leadership as a moderating variable at PT. Astra International Tbk. - Toyota Sales Operation (TSO). The research method used is Partial Least Square (PLS) to analyze data collected through questionnaires from sales force, sales force leaders, and sales program sections at PT. Astra International Tbk. - TSO. The results of the study indicate that Sales Force Competence has a positive and insignificant influence on Sales Performance. Sales programs have a positive and significant influence on sales performance. In addition, the interaction between sales force and leadership does not have a significant influence on sales performance and its influence tends to be negative with a very low moderation effect. And the interaction between sales programs and leadership has a positive and significant influence on sales performance, although the moderation effect remains low. This study is expected to provide practical implications for companies in improving sales performance through the development of sales force competence, optimization of sales programs, and the application of the right leadership style.
Co-Authors Arief Nurrochmad Hanafi, Arif Riswahyudi Harman Harman, Harman Tallo Adu, Yuliana Wahyudi, Danang Tri