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Emerging Trends in Peripheral Artery Disease: A Review of Recent Studies: A Literature Review Zelda Rizkylia Meidinar Ardis; Wayan Dhea Agastya
Journal of Diverse Medical Research : Medicosphere Vol. 1 No. 2 (2024): J Divers Med Res 2024
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i2.134

Abstract

Abstract Background. Peripheral artery disease (PAD) is a chronic vascular condition characterized by the narrowing or blockage of peripheral arteries, primarily affecting the lower extremities. It is a major manifestation of atherosclerosis and a significant contributor to cardiovascular morbidity and mortality worldwide. The disease disproportionately affects older adults, smokers, individuals with diabetes, and those with a history of hypertension or hyperlipidemia. Methods. Existing scholarly work was explored through PubMed, Google Scholar, and Scopus, using relevant keywords, such as "peripheral artery disease," "diabetes," "atherosclerosis,” and “short-chain fatty acids.” Discussion. The global burden of PAD has risen, driven by aging populations and increasing prevalence of risk factors. Advances in diagnostic techniques, medical therapies, and interventional approaches have expanded treatment options, but challenges persist in ensuring early detection, equitable access, and effective long-term management. This review aims to synthesize the latest literature on PAD, emphasizing recent developments and identifying gaps that warrant further exploration. Conclusion. The objective of this review is to synthesize recent advancements in our understanding, diagnosis and management of peripheral artery disease (PAD). Peripheral Arterial Disease is a chronic, progressive vascular disorder with significant global health implications. The paper examines the complex relationship between PAD and type 2 diabetes mellitus (T2DM), a prevalent comorbidity linked to increased disease severity and unfavorable outcomes due to shared pathological mechanisms such as endothelial dysfunction, chronic inflammation, and atherosclerosis. Furthermore, it explores emerging treatment strategies, including novel pharmacological agents and innovative therapeutic technologies aimed at enhancing perfusion and mitigating disease progression. Keywords: Peripheral artery disease, diabetes, atherosclerosis, endovascular treatment, short-chain fatty acids, glucose control
Enhancing Emergency Fracture Diagnosis with Point-of-Care Ultrasound (Pocus) : A Rapid and Efficient Alternative: A Literature Review Wayan Dhea Agastya; Amalia Rahmadinie; Khansa Tsabitah Aulia; Fakhirah Nailah Anrofi; Alya Raguan Al Habsyi; Shofie Ayu Nur Firdausiyah; Bisarda Kanira Permata Putri Winangest
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 5 (2025): J Divers Med Res 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i5.177

Abstract

Abstract Introduction: Fracture diagnosis is a crucial aspect of trauma and musculoskeletal injury management, traditionally relying on imaging modalities such as X-ray, CT scan, and MRI. However, these methods have limitations, including high costs, long waiting times, radiation exposure, and limited accessibility in remote areas. Point-of-Care Ultrasound (POCUS) has emerged as a diagnostic alternative that is more portable, cost-effective, radiation-free, and provides real-time results, making it a potential solution in emergency situations or resource-limited healthcare facilities. Methods: This study employs a literature search approach based on the PICO framework to evaluate the effectiveness of Point-of-Care Ultrasound (POCUS) in detecting fractures compared to X-ray, CT scan, and MRI. Literature sources were obtained from Scopus, ScienceDirect, Google Scholar, and PubMed using relevant keywords. Seven English-language journals were selected for further analysis. Results and Disscussion: POCUS is a rapid, non-invasive, and effective diagnostic tool for fracture and musculoskeletal injury. It allows fracture identification within an average of 3.9 minutes, with a sensitivity exceeding 85%, reaching up to 100% in children, while its specificity exceeds 90%. Although its accuracy is still lower than that of MRI, POCUS excels in terms of speed and patient convenience. Conclusion: POCUS serves as a safe and rapid alternative to conventional methods, particularly for children and patients with limited access to radiographic imaging. It provides a more patient-friendly diagnostic method, especially in medical settings requiring high safety and speed. While X-ray remains the gold standard, POCUS can be utilized in emergency situations. However, its effectiveness depends on operator skill and is less optimal for detecting complex fractures. Keywords: Point-of-Care-Ultrasound, POCUS, Fracture, Diagnosis, Medical Imaging
Optimizing Acute Pain Management After Trauma in the Emergency Department: the Role of Regional Nerve Blocks by Anesthesiologists: A Literature Review Wayan Dhea Agastya; Amalia Rahmadinie
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 7 (2025): J Divers Med Res 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i7.178

Abstract

Abstract Background: Acute pain management remains a critical challenge in emergency departments (EDs), particularly in trauma cases. Traditional systemic analgesics, especially opioids, pose risks of adverse effects and dependency. Regional nerve blocks (RNBs), administered by anesthesiologists, offer a promising alternative. This literature review explores the efficacy, safety, and practical considerations of RNBs in trauma-related acute pain within ED settings. Evidence suggests that RNBs significantly reduce pain scores and opioid consumption while maintaining a favorable safety profile. Collaborative implementation of RNBs in EDs can improve patient outcomes and reduce opioid-related risks. Method: This research employs a literature analysis approach by reviewing relevant theoretical and empirical sources, including Google Scholar, PubMed, and ScienceDirect. Discussion: The findings reveal that RNBs, particularly when guided by ultrasound and performed by anesthesiologists, significantly reduce pain scores, opioid use, and side effects compared to systemic analgesia. Despite logistical barriers in ED settings, collaborative approaches between emergency physicians and anesthesiologists enhance feasibility and patient outcomes. Conclusion: Regional nerve blocks by anesthesiologists offer fast, targeted, and safer pain relief in trauma care, reducing opioid dependence and improving outcomes. Integrating RNBs into emergency protocols enhances patient care and should be prioritized. Keywords: Regional Nerve Block, Trauma Pain, Emergency Department, Anesthesiologist