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Efektivitas Blok Saraf Tepi Transversus Abdominis Plane (TAP) terhadap Nyeri Pascaoperasi Seksio Sesarea Darurat dalam Kondisi Bencana: Penelitian Kohort Retrospektif Agastya, Wayan Dhea; Rahmadinie, Amalia; Sepviyanti Sumardi, Fitri
Jurnal Anestesi Obstetri Indonesia Vol 8 No 2 (2025): Juli
Publisher : Indonesian Society of Obstetric Anesthesia and Critical Care (INA-SOACC)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47507/obstetri.v8i2.226

Abstract

Latar Belakang: Tsunami Palu 2018 menyebabkan peningkatan tajam tindakan seksio sesarea darurat di RSUD Undatta. Dalam kondisi keterbatasan, pendekatan analgesia regional seperti blok saraf tepi Transversus Abdominis Plane (TAP) block dapat menjadi strategi efektif untuk menekan kebutuhan opioid dan mempercepat pemulihan pasien. Tujuan: Menilai efektivitas Blok saraf tepi TAP dalam mengurangi nyeri pascaoperasi dan konsumsi opioid pada pasien seksio sesarea darurat dalam situasi bencana. Metode: Penelitian kohort retrospektif terhadap 100 pasien yang menjalani seksio sesarea darurat selama Oktober–November 2018. Dibandingkan dua kelompok: Blok saraf tepi TAP (n=50) vs analgesia sistemik konvensional (n=50). Parameter evaluasi: skor Visual Analog Scale (VAS) pada 1, 6, 12, 24 jam; konsumsi morfin ekuivalen; dan komplikasi. Hasil: Skor nyeri VAS kelompok TAP signifikan lebih rendah di semua titik waktu (p<0.01), dengan rata-rata skor VAS 24 jam: 2.0 ± 0.9 (vs 4.7 ± 1.3). Penggunaan morfin juga berkurang secara signifikan (1.5 mg vs 4.3 mg; p<0.01). Tidak ada komplikasi berat; 4% pasien TAP mengalami parestesia ringan. Simpulan: Blok TAP efektif dan aman sebagai analgesia pascaoperasi untuk seksio sesarea darurat dalam kondisi bencana. Teknik ini layak diintegrasikan ke dalam protokol anestesi kebencanaan
Implementasi Program Pendayagunaan Dokter Spesialis sebagai Salah Satu Bentuk Pengabdian Masyarakat di Daerah Rahmadinie, Amalia; Agastya, Wayan Dhea
Jurnal Peduli Masyarakat Vol 7 No 4 (2025): Jurnal Peduli Masyarakat: Juli 2025
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jpm.v7i4.6875

Abstract

Kesenjangan akses pelayanan kesehatan antara daerah perkotaan dan pedesaan masih menjadi tantangan serius di Indonesia. Program pendayagunaan dokter spesialis atau disingkat PGDS dirancang untuk mengatasi kekurangan tenaga dokter spesialis di daerah. Artikel ini bertujuan untuk menggambarkan implementasi program PGDS, khususnya dokter spesialis anestesi, sebagai bentuk pengabdian masyarakat di daerah. Metode yang digunakan adalah studi deskriptif kuantitatif, data dikumpulkan secara retrospektif dari rekam medis pasien, dan meliputi seluruh pasien yang mendapatkan pelayanan anestesi oleh dokter PGDS selama masa penempatan dari Desember 2021 sampai dengan Nopember 2022. Literatur yang digunakan dibatasi pada publikasi dalam 10 tahun terakhir untuk menjaga keterkinian informasi dan relevansi konteks kebijakan. Dapat terlihat bahwa program ini telah memberikan kontribusi positif terhadap akses layanan kesehatan di daerah, walaupun menghadapi berbagai tantangan seperti keterbatasan infrastruktur dan fasilitas serta keberlanjutan penempatan dokter yang masih perlu dibenahi. Pelaksanaan PGDS di daerah adalah strategi efektif dalam pemerataan layanan kesehatan di Indonesia sekaligus sebagai salah satu bentuk pengabdian terhadap masyarakat.
Evaluating the Role of Atropine Sulphate in Preventing Motion-Related Postoperative Nausea and Vomiting in Patients Undergoing Cesarean Section using ERACS Protocol Rahmadinie, Amalia; Agastya, Wayan Dhea
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 14 No. 1 (2025): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v14i1.24123

Abstract

ABSTRACT Background: PONV is common after cesarean section using ERACS protocol. Motion-related PONV during early mobilization can impair comfort and delay recovery. Anticholinergic agents such as atropine sulphate have antiemetic effects via muscarinic receptor antagonism, especially when vestibular pathways are involved, but their intravenous use for motion-related PONV prevention remains underexplored. Objective: To evaluate the effectiveness of intravenous atropine sulphate in reducing motion-related PONV within two hours postoperatively in patients undergoing cesarean section. Methods: A retrospective cross-sectional analysis was carried out involving 30 patients at a private hospital in Sidoarjo, Indonesia (May–June 2025). Patients were assigned to either control (no atropine) or treatment (0.5 mg atropine IV after cord clamping). The primary outcome was a combined PONV score: (1) vomiting episodes ≥ 1, (2) moderate-to-severe nausea/vomiting (VAS > 4), and (3) rescue antiemetic use. Secondary outcomes included atropine-related adverse effects. Results: The treatment group had significantly lower mean combined PONV scores (p < 0.001), fewer vomiting episodes (p = 0.035), less moderate-to-severe nausea (p = 0.002), and borderline reduced rescue antiemetic use (p = 0.05). No significant adverse effects were observed. Conclusion: IV atropine sulphate 0.5 mg after cord clamping effectively reduces motion-related PONV in ERACS cesarean patients without notable side effects. Keywords: atropine sulphate, cesarean section, ERACS, PONV vestibular pathway.
A Narrative Review Hospital Disaster Management as a Strategic Component of the National Emergency Response System: A Narrative Review Wayan Dhea Agastya; Amalia Rahmadinie; Ayesha Jasmine Firdausi
Journal of Diverse Medical Research : Medicosphere Vol. 3 No. 3 (2026): Journal of Diverse Medical Research : Medicosphere 2026
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v3i3.307

Abstract

Hospitals constitute a critical pillar of national emergency response systems, particularly in disaster-prone regions. Beyond their clinical function, hospitals act as coordination hubs for medical response, triage, logistics, and intersectoral collaboration. This narrative review critically examines the strategic role of hospitals in disaster management across preparedness, mitigation, response, and recovery phases. Evidence from international guidelines, peer-reviewed studies, and Indonesian experiences indicates that structured hospital disaster management significantly improves operational resilience, continuity of essential services, and patient outcomes. Strengthening hospital disaster preparedness through standardized planning, regular simulations, and incident command systems is essential for enhancing health system resilience and reducing disaster-related morbidity and mortality.
The Effectiveness of Health Promotion on the Prevention of Urolithiasis: Narrative Literature Review Yogi Bisma Widawasista; Irma Seliana; Wayan Dhea Agastya
Jurnal Kesehatan dan Kedokteran Vol. 5 No. 1 (2026): Februari: Jurnal Kesehatan dan Kedokteran
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/jukeke.v5i1.2389

Abstract

Urolithiasis remains a significant public health problem due to its high recurrence rate and strong association with lifestyle-related risk factors, such as inadequate hydration and unhealthy dietary habits. Preventive efforts through health promotion are therefore essential, not only to reduce recurrence but also to support broader public health goals, including the achievement of Sustainable Development Goal (SDG) 3. Objective: This study aimed to review the effectiveness of health promotion interventions in preventing urolithiasis between 2020 and 2025 and to examine their contribution to achieving SDG 3. Method: This study employed a narrative literature review design using secondary data from articles published between 2020 and 2025. The literature was retrieved from Google Scholar, GARUDA, and university journal portals. Selected studies were analysed descriptively and thematically to identify the types of health promotion interventions and their reported outcomes in urolithiasis prevention. Findings: The review showed that health promotion interventions were effective in improving knowledge, attitudes, and preventive behaviours related to urolithiasis. Community-based and school-based programs increased awareness of adequate hydration, healthy dietary patterns, and water-consumption habits, demonstrating their positive contribution to prevention efforts. Implications: These findings suggest that health promotion is a practical and cost-effective strategy for preventing urolithiasis and may also support broader non-communicable disease prevention initiatives aligned with SDG 3. The integration of digital health approaches is recommended to strengthen program sustainability and encourage long-term behavioural change. Originality: This review provides a focused synthesis of post-2020 evidence on preventive health promotion strategies for urolithiasis. Its value lies in extending the discussion beyond clinical management by offering context-specific insights that contribute to public health practice and preventive health policy.
Opioid-Sparing and Multimodal Analgesia in Cesarean Delivery: A Systematic Review of Evidence and Implementation Across High and Low-Middle Income Countries: A Systematic Review Wayan Dhea Agastya; Amalia Rahmadinie
Journal of Diverse Medical Research : Medicosphere Vol. 2 No. 9 (2025): J Divers Med Res 2025
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v2i9.214

Abstract

ABSTRACT Introduction: Cesarean delivery is a common surgical procedure worldwide, often accompanied by significant postoperative pain that can negatively impact recovery, early breastfeeding, and maternal mobility. Opioids have traditionally been central to post-cesarean analgesia but are associated with side effects such as nausea, vomiting, pruritus, sedation, and respiratory depression. Recently, opioid-sparing and multimodal analgesia strategies—combining neuraxial opioids, regional blocks (e.g., transversus abdominis plane [TAP] block), and non-opioid systemic agents (NSAIDs, acetaminophen)—have been increasingly adopted to reduce opioid consumption while maintaining effective analgesia. Methods: A systematic literature search was conducted in PubMed, Scopus, Web of Science, and Google Scholar for studies published from January 2021 to August 2025. Eligible studies included randomized controlled trials, cohort studies, and quality improvement projects evaluating opioid-sparing multimodal analgesia in women undergoing cesarean delivery in both high-income countries (HICs) and low- and middle-income countries (LMICs). Primary outcomes were postoperative opioid consumption and pain scores; secondary outcomes included opioid-related side effects, recovery milestones, maternal satisfaction, and neonatal safety. Data extraction and quality assessment were performed independently by two reviewers following PRISMA 2020 guidelines. Discussion: The review included nine studies from diverse settings. Multimodal analgesia regimens consistently reduced opioid consumption and pain scores, improved maternal satisfaction, and decreased opioid-related adverse effects. Regional techniques such as TAP block were effective adjuncts or alternatives to neuraxial opioids, especially in LMICs where opioid availability and monitoring are limited. Adoption of multimodal protocols was more widespread in HICs, often integrated within enhanced recovery after cesarean (ERAC) pathways. Barriers in LMICs included limited regional anesthesia expertise, drug availability, cost, and institutional protocols, highlighting the need for capacity building and context-specific guidelines. Conclusion: Opioid-sparing multimodal analgesia is effective, safe, and feasible across various healthcare settings, improving postoperative pain control and recovery after cesarean delivery. Addressing implementation gaps between HICs and LMICs through training, resource allocation, and simplified protocols is essential to optimize global obstetric analgesia. Future research should focus on standardizing regimens, evaluating long-term maternal and neonatal outcomes, and overcoming implementation challenges to facilitate broader adoption.
Disaster Medicine in Low-Resource Settings Recent Challenges and Innovations Wayan Dhea Agastya
Journal of Diverse Medical Research : Medicosphere Vol. 1 No. 4 (2024): J Divers Med Res 2024
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i4.19

Abstract

Background. Disaster medicine in low-resource settings faces many challenges. Most are aggravated by limited infrastructure, scarce medical supplies, and insufficiently trained health professionals. This calls for complexity in responding to these events due to enhanced logistic challenges and sociopolitical instability, according to which may hamper effective and timely medical interventions. Methods. Literature searching was conducted using databases such as PubMed, Google Scholar, and Web of Science using Search terms included "disaster medicine," "low-resource settings," "emergency response," and "innovations in disaster care.". Systematic reviews of peer-reviewed articles, reports, and case studies were chosen.
Impact of Technology on Disaster Medicine in Low-Resource Settings: A Literature Review Wayan Dhea Agastya
Journal of Diverse Medical Research : Medicosphere Vol. 1 No. 5 (2024): J Diverse Med Res
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i2.25

Abstract

AbstractBackground. Technology has become a key to face challenges in improving disaster medicine services in low resources settings. By using technology, some obstacles can be solved and increase the quality of the services. Methods. Literature searching was conducted using databases such as PubMed, Google Scholar, and Web of Science using Search terms included "disaster medicine," "low-resource settings," "emergency response," and "innovations in disaster care.". Systematic reviews of peer-reviewed articles, reports, and case studies were chosen.Discussion. Some key innovations which can be used include mobile health (mHealth) solutions, telemedicine, portable medical devices, drones, geographic information systems (GIS), and wearable health monitors. These tools have significantly improved disaster response by enhancing communication, enabling remote diagnostics, optimizing resource allocation, and ensuring continuous care. Telemedicine platforms have proven invaluable during crises like the COVID-19 pandemic, while portable devices and renewable energy solutions maintain medical operations amid power disruptions. Drones and GIS support timely delivery of medical supplies and effective disaster planning.Conclusion. Future strategies advocate for integrating artificial intelligence, robust governance, community engagement, and innovative research to enhance disaster resilience. This review underscores the critical need for sustainable, technology-driven approaches in disaster medicine to mitigate health disparities and improve outcomes in vulnerable populations. Keywords. disaster medicine, low resources, healthcare, technology
Advancements in Understanding and Managing Parkinson's Disease: A Review of Recent Literature: A Literature Review Rafi Auliya Arbani Arbani; Wayan Dhea Agastya
Journal of Diverse Medical Research : Medicosphere Vol. 1 No. 1 (2024): J Divers Med Res 2024
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i1.34

Abstract

Background : Parkinson's Disease (PD) remains a complex and challenging condition, with ongoing research shedding light on its multifaceted nature. This review synthesizes recent findings on the genetic basis, autonomic dysfunction, lifestyle impacts, treatment advancements, and environmental considerations related to PD. By analyzing recent literature, this review aims to provide a comprehensive understanding of current trends and implications for future research and clinical practice. Methods : Literature searches were performed using databases including PubMed, Google Scholar, and SINTA with search terms such as "Parkinson’s" "Genetics" "lifestyle" and "environtment" Only systematic reviews of peer-reviewed articles, reports, and case studies were selected for inclusion. Discussion : The complexity of Parkinson's Disease (PD) and the necessity for a multidimensional approach to its understanding and management. Genetic research highlights opportunities for personalized medicine, while insights into autonomic dysfunction underscore the importance of comprehensive clinical evaluations. Lifestyle and environmental factors are increasingly recognized for their roles in PD prevention and management, advocating for a holistic approach. Advancements in treatment, including immunotherapy and neural grafting, provide hope for improved patient outcomes, though significant challenges remain in translating research into clinical practice. Conclusion : This review highlights the multifaceted nature of Parkinson's Disease, emphasizing the importance of integrating genetic, lifestyle, and environmental considerations into clinical practice. Recent advancements in understanding PD's underlying mechanisms and therapeutic innovations provide a foundation for improved management and prevention. A holistic and multidisciplinary approach is essential to enhance patient outcomes and address the challenges in diagnosing and treating this complex neurodegenerative disorder.
The Impact of Pneumococcal Conjugate Vaccines on Pneumonia in Children: A Review of Recent Studies Putri Noviana Agustina; Wayan Dhea Agastya
Journal of Diverse Medical Research : Medicosphere Vol. 1 No. 3 (2024): J Divers Med Res 2024
Publisher : Faculty of Medicine - Universitas Pembangunan Nasional Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i3.131

Abstract

Background. The introduction of pneumococcal conjugate vaccines (PCVs) has significantly reduced the burden of pneumonia in children worldwide, leading to decreased hospitalization rates, lower severity of disease, and a reduction in antibiotic resistance. However, regional disparities persist, particularly in low- and middle-income countries where healthcare infrastructure and access to vaccines are often limited. Methods. This review synthesizes findings from recent studies on the impact of PCVs on the incidence, severity, and management of pneumonia in children. It includes analyses of studies conducted in various regions, highlighting the global and regional effects of PCVs on pneumonia hospitalization rates, vaccine effectiveness against severe disease, and antibiotic resistance. Discussion. The review underscores the importance of PCVs in reducing pneumonia-related hospitalization rates, disease severity, and antibiotic resistance globally. Nevertheless, challenges persist in addressing regional disparities, particularly in underserved areas with limited healthcare infrastructure and vaccine accessibility. Conclusion. Continued surveillance and research are essential to evaluate the long-term effectiveness of newer PCV formulations. Developing strategies to improve vaccination coverage in underserved populations and monitoring the emergence of new serotypes are critical for adapting public health strategies. By addressing these challenges, the protective benefits of PCVs can be sustained, ultimately improving health outcomes for children Keywords:Pneumococcal conjugate vaccine, pneumonia, children, hospitalization, vaccine effectiveness, antibiotic resistance