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All Journal Inovasi Kesehatan Global Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Dila Alvia Rahmasari
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health

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Artikel Riview: Pengaruh Penggunaan Matriks Pada Tablet Lepas Lambat Maulina Apriani; Dian Ayu Oktavia; Isnaini Sukmaning M; Dila Alvia Rahmasari; Zahwa Natasya Novita P; Alvito Syawal Z; Dewi Rahmawati; Dzakiya Zhihrotulwida; Yani Ambari; M. Fithrul Mubarak
Inovasi Kesehatan Global Vol. 2 No. 2 (2025): Mei : Inovasi Kesehatan Global
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ikg.v2i2.1580

Abstract

Sustained-release tablets are pharmaceutical preparations designed to gradually release the active substance over a specific period, thereby maintaining a constant concentration of the drug in the circulatory system and enhancing therapeutic effectiveness.The development of sustained-release tablets aims to extend the duration of drug action, reduce the frequency of dose administration, and minimize fluctuations in drug levels in the plasma, which ultimately enhances patient compliance and treatment effectiveness, especially in chronic diseases.The purpose of this review is to identify various formulation methods and innovations in the production of sustained-release tablets, as well as to examine the factors that influence the success of these formulations.The method used in this study is a literature review that collects data from various scientific publications over the past five years through online platforms such as Google Scholar, using keywords related to matrix sustained-release tablets and pharmaceutical formulations.The results of the review indicate that various techniques, such as formulating polymer matrices, coating, and encapsulation, have been applied with varying degrees of success depending on the type of active ingredients and excipients used. Some formulation innovations, such as the use of natural polymer matrices and matrix modifications, have proven effective in achieving controlled, stable, and quality-standard-compliant drug release.
Artikel Review : Efektivitas dan Keamanan Berbagai Rute Pemberian Obat Injeksi Suspensi Dila Alvia Rahmasari; Maulina Apriani; Amina Syifa; Dewi Febiyanti; Nurul Islami Ningtiyas; Nabilla Navyani Putry A; Dewi Rahmawati; Dzakiya Zhihrotulwida; M.Fithrul Mubarok
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 4 No. 1 (2026): Januari: OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v4i1.2036

Abstract

Advances in technology and research in the field of pharmacy have driven innovation in drug formulation and administration methods to improve the effectiveness and safety of therapy. One of the most widely developed dosage forms is suspension injections, which are sterile preparations containing particles of active ingredients that are insoluble in the carrier fluid. This study aims to review the effects of various administration routes, such as intra-articular, intramuscular, and subcutaneous, on the efficacy and safety of suspension injections. The method used is a literature study analyzing various scientific journals from databases published in the last ten years. The results of the review show that the route of administration has a significant effect on the therapeutic effect, where the intra-articular route provides a strong local effect with low systemic risk, the intramuscular route produces long-term effects and is relatively easy to perform, while the subcutaneous route provides stable drug release over a long period of time. Overall, the choice of injection route for suspension injections should be tailored to the characteristics of the drug, the patient's condition, and the therapeutic goals to achieve optimal, safe, and comfortable treatment outcomes for the patient.
Co-Authors Alvito Syawal Z Amina Syifa Dewi Febiyanti DEWI RAHMAWATI Dian Ayu Oktavia Dzakiya Zhihrotulwida Isnaini Sukmaning M M. Fithrul Mubarak M.Fithrul Mubarok Maulina Apriani Nabilla Navyani Putry A Nurul Islami Ningtiyas Yani Ambari Zahwa Natasya Novita P