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All Journal Oto Rhino Laryngologica Indonesiana
Handayani, Ni Komang Tri Utami
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Health Professions Medicine & Pharmacology

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The relationship between IL-6 expression and ossicular destruction in CSOM with cholesteatoma Rahayu, Made Lely; Winarti, Ni Wayan; Danastri, I Gusti Ayu Mahaprani; Handayani, Ni Komang Tri Utami; Reniati, Roselina
Oto Rhino Laryngologica Indonesiana Vol. 55 No. 1 (2025): VOLUME 55, NO. 1 JANUARY - JUNE 2025
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v55i1.704

Abstract

Background: Chronic suppurative otitis media (CSOM) is a disease that affects the middle ear, leading to perforation of the tympanic membrane. This condition involves chronic inflammation in the middle ear and mastoid cavity. A CT scan often reveals destruction to the ossicles and cholesteatoma. Purpose: To determine the relationship between increased IL-6 expression and ossicular destruction in CSOM patients with cholesteatoma. Method: This observational analytic study with a cross-sectional comparative design was conducted at the Anatomy Pathology Laboratory of Prof. Ngoerah General Hospital, Denpasar. The study used cholesteatoma tissue paraffin blocks from patients with the dangerous type of CSOM who had undergone tympanomastoidectomy from January 2022 to December 2023. Sampling was carried out through consecutive sampling, which included all cholesteatoma tissue paraffin blocks from patients with the dangerous type of CSOM that met the inclusion criteria, amounting to 17 blocks. Result: This study found a p-value >0.05, indicating no association in the bivariate analysis between the percentage, intensity, and overall score of IL-6 pathology results and ossicular destruction due to cholesteatoma, in CSOM patients. Conclusion: This study concluded that there was no significant relationship between IL-6 expression and hearing bone destruction caused by cholesteatoma in CSOM patients.
Difficulties in the removal of whistle foreign body in the left bronchus Handayani, Ni Komang Tri Utami; Sucipta, I Wayan; Putra, I Dewa Gede Arta Eka; Asthuta, Agus Rudi; Suanda, I Ketut; Dewantara, I Putu Santhi
Oto Rhino Laryngologica Indonesiana Vol. 55 No. 2 (2025): VOLUME 55, NO. 2 JULY - DECEMBER 2025
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v55i2.715

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Background: Tracheobronchial foreign bodies are one of the most common critical conditions in otorhinolaryngology. The mortality rate due to foreign body aspiration in children under 5 years old is quite high. The increased incidence of foreign body aspiration was triggered by the tendency of children to put everything in their mouths when crying, screaming, running, and playing. Purpose: To report difficulties in the management of a whistle foreign body in the left bronchus. Case report: A 9 years old boy, was brought to Prof. Ngoerah Hospital on December 19th, 2023, with a complaint of coughing for 2 days, because he accidentally choked on a whistle while playing. However, the results of thoracic X-ray and CTscan did not show a clear foreign body in the form of a whistle. Method: Literature search was conducted using keywords ”whistle foreign body in left bronchus” OR ”whistle foreign body” OR ”foreign body in left bronchus” AND ”bronchoscopy management” in Medline and PubMed from 2019– 2024. Result: A total of 21 literatures was found, and 12 could be used as references. Conclusion: The management of foreign body in the bronchus is challenging in diagnostic and bronchoscopy procedures.
Co-Authors Asthuta, Agus Rudi Danastri, I Gusti Ayu Mahaprani Dewantara, I Putu Santhi I Wayan Sucipta, I Wayan Ni Wayan Winarti Putra, I Dewa Gede Arta Eka Rahayu, Made Lely Reniati, Roselina Suanda, I Ketut