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Pengendalian Konsumsi Gula Dalam Mencegah Penyakit Diabetes Melitus Tipe II Di Usia Dini Lestari, Trisna; Bachtiar, Arsyad; Kurniawa, Agus; Feyki, Della Fitrian; Melina, Melina; Fitri, Aisyah Nur; Baqiyatusshalihah, Ratu Binar; Rizky, Muhammad; Audriana, Reza; Luthfiah, Ade Sofi; Dipriana, Dipriana
Abdi Geomedisains Vol. 6, No. 1, June 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/abdigeomedisains.v6i1.6892

Abstract

Diabetes Mellitus (DM) is a chronic disease caused by a lack of insulin production or resistance to insulin, which leads to increased glucose levels in the body. This disease has an increasing prevalence, both in developed and developing countries, and is becoming a global health problem. One of the main factors at risk of increasing DM is lifestyle and habits, especially the habit of consuming sweet foods and lack of physical activity. This research aims to provide education about controlling sugar consumption in preventing Type II Diabetes Mellitus at an early age, with a focus on PMR MTSN 1 Cirebon students. The method used is direct outreach in the form of counseling with presentations using PPT and LCD. This research used convenience sampling techniques and involved 36 students as respondents. Data collection was carried out through pretest and posttest with a questionnaire containing 10 questions to assess knowledge about DM and the impact of excessive sugar consumption. The data obtained were analyzed using the Paired t-Test with IBM SPSS Statistics Version 17.0 software to determine differences in knowledge before and after counseling. It is hoped that the results of the research will increase teenagers' awareness of the importance of a healthy lifestyle, especially in controlling sugar consumption, in order to prevent Type II Diabetes Mellitus.
Efficacy of Vasopressin-Methylprednisolone Vs Placebo for in-Hospital Cardiac Arrest: Systematic Review Fatimah, Fatimah; Alfino, Alfino; Darma, Ghina Malya; Fitri, Aisyah Nur
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6565

Abstract

Intrahospital cardiac arrest (IHCA) has a high mortality (70-90%) despite standard resuscitation. The combination of vasopressin and methylprednisolone has been proposed as an adjuvant therapy to improve Return of Spontaneous Circulation (ROSC) and patient outcomes, but evidence of its effectiveness on long-term survival remains controversial. Objective to evaluate the efficacy of vasopressin-methylprednisolone combination versus placebo in IHCA patients for ROSC, survival, and neurologic outcomes. This systematic review study used the PICO framework (Population: Cardiac Arrest In-Hospital Patients; Intervention: Vasopressin + Methylprednisolone; Comparison: Placebo; Outcome: ROSC) and Randomized Controlled Trials (RCT) study design. A search in PubMed, ScienceDirect, and Google Scholar using the keywords "Vasopressin, Cardiac Arrest In-Hospital, Methylprednisolone, ROSC" resulted in a total of 769,070 initial articles. After screening based on access criteria, language, design, and publication year (2020-2025), 196 articles remained. Further eligibility selection based on sample suitability and specific interventions resulted in 41 potential articles. The final analysis to answer the question of the effect of the combination of Vasopressin and Methylprednisolone on ROSC found 3 RCT journals (from PubMed) that met all inclusion criteria. The combination of vasopressin-methylprednisolone significantly increased ROSC (42% vs. 33%; RR 1.30; 95% CI 1.03–1.63; *p* = 0.03), especially when given ≤8 minutes after cardiac arrest (51% vs. 35%). However, there were no significant differences in 30-day (9.7% vs. 12%; RR 0.83) or 1-year survival (6.3% vs. 8.3%; RR 0.76), favorable neurologic outcome (Cerebral Performance Category 1–2: 7.6% vs. 7.6%), or quality of life (EQ-5D-5L score). Adverse events (hyperglycemia, hypernatremia) were similar between groups. The combination of vasopressin-methylprednisolone effectively improves ROSC but has no impact on long-term survival or neurological recovery. Further studies are needed to identify subpopulations that benefit and explore post-ROSC therapeutic strategies.