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The Effectiveness of Combining Antibiotics and Antioxidants in the Treatment of Acute Bacterial Respiratory Tract Infections Atjo, Neng Mira; Tanggono, Aninda
Jurnal Ar Ro'is Mandalika (Armada) Vol. 5 No. 2 (2025): JURNAL AR RO'IS MANDALIKA (ARMADA)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/armada.v5i2.4944

Acute bacterial respiratory tract infections (ABRTIs) remain a significant public health concern, particularly due to increasing antibiotic resistance and the resulting decline in treatment efficacy. In response, researchers have explored adjunctive therapies, including antioxidants, to enhance antibiotic performance and reduce oxidative stress-related complications. This study aims to evaluate the effectiveness of combining antibiotics with antioxidants in treating ABRTIs by employing a qualitative approach through systematic literature review and library research. Data were collected from peer-reviewed journals, scientific databases, and relevant academic publications spanning the last two decades. The findings reveal that oxidative stress plays a crucial role in the progression and severity of bacterial infections in the respiratory tract. Antioxidants such as N-acetylcysteine, vitamin C, and glutathione have shown promising synergistic effects when combined with conventional antibiotics. These combinations not only improve microbial clearance but also minimize tissue damage and inflammatory responses. Furthermore, the literature indicates a potential role for antioxidants in mitigating antibiotic-induced toxicity and in restoring immune balance. However, despite encouraging preclinical and limited clinical data, there remains a lack of large-scale, randomized controlled trials to confirm the therapeutic advantage of this combination. The study concludes that while the integration of antioxidants into antibiotic therapy appears promising, further empirical validation is essential. These findings highlight the importance of continued interdisciplinary research to optimize therapeutic protocols for ABRTIs.

The Role of Telemedicine in Improving Access to Healthcare Services in Remote Areas Tanggono, Aninda; Hidayat, Rachmad
Jurnal Ar Ro'is Mandalika (Armada) Vol. 5 No. 2 (2025): JURNAL AR RO'IS MANDALIKA (ARMADA)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59613/armada.v5i2.5138

The rapid advancements in information and communication technologies (ICT) have revolutionized healthcare delivery, particularly in remote and underserved areas. One of the most significant innovations is telemedicine, which has emerged as a critical tool for overcoming geographical barriers and improving access to healthcare services. This paper explores the role of telemedicine in enhancing healthcare delivery in remote areas, where traditional healthcare infrastructure is often limited or non-existent. The study examines various telemedicine models, their implementation, and the outcomes observed in different remote regions, with a particular focus on the advantages and challenges associated with telemedicine. The research highlights the ways in which telemedicine bridges the gap between healthcare providers and patients in rural or isolated locations, ensuring that individuals in these areas can receive timely medical consultations, diagnoses, and treatments. It discusses the use of telemedicine in various specialties, including primary care, mental health, emergency services, and chronic disease management, emphasizing its versatility and potential to improve health outcomes. Furthermore, the paper addresses the technological, regulatory, and social barriers that may hinder the effective implementation of telemedicine, such as internet connectivity issues, data privacy concerns, and resistance to technology adoption. Through case studies and empirical evidence, the paper presents successful examples of telemedicine initiatives in different regions, demonstrating the positive impact on healthcare access, patient satisfaction, and healthcare cost reduction. Additionally, it explores the potential future developments in telemedicine, including the integration of artificial intelligence (AI) and other emerging technologies to further enhance healthcare delivery in remote areas. Telemedicine plays a pivotal role in improving access to healthcare services in remote areas, contributing to more equitable healthcare systems globally. The paper suggests that with the right policies, infrastructure, and support systems, telemedicine has the potential to become a cornerstone of modern healthcare delivery, particularly in regions with limited access to traditional healthcare facilities. Future research should focus on addressing the challenges of scaling telemedicine and exploring its long-term impact on healthcare systems worldwide.

The Effect of Preoxygenation on the Incidence of Desaturation During Induction of General Anesthesia Tanggono, Aninda
Riwayat: Educational Journal of History and Humanities Vol 8, No 3 (2025): July, Social Studies, Educational Research and Humanities Research.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v8i3.48124

Desaturation during induction of general anesthesia is a significant clinical concern, leading to complications such as hypoxia and impaired organ function. Preoxygenation is a common practice aimed at increasing the oxygen reserves in the body, thereby reducing the risk of desaturation. However, the effectiveness of preoxygenation in minimizing desaturation during anesthesia induction remains a topic of debate. This study aims to investigate the effect of preoxygenation on the incidence of desaturation during the induction of general anesthesia. To determine whether preoxygenation reduces the incidence of desaturation during the induction of general anesthesia and to identify factors influencing its effectiveness. This prospective cohort study was conducted with a sample of 150 patients undergoing elective surgeries requiring general anesthesia. Participants were randomly assigned to two groups: the preoxygenation group, where patients received 3-5 minutes of preoxygenation with 100% oxygen via a face mask, and the control group, where patients did not undergo preoxygenation. Desaturation, defined as a drop in oxygen saturation (SpO2) below 90%, was monitored continuously during the induction phase. Data were analyzed using statistical tests to compare the incidence of desaturation between the two groups. The preoxygenation group demonstrated a significantly lower incidence of desaturation compared to the control group. The incidence of desaturation was 10% in the preoxygenation group, compared to 25% in the control group (p0.05). Furthermore, preoxygenation was particularly effective in patients with higher body mass index (BMI) and those undergoing longer surgical procedures. Preoxygenation significantly reduces the incidence of desaturation during the induction of general anesthesia, suggesting it is a valuable practice in improving patient safety. The findings support the use of preoxygenation, particularly in patients with higher BMI or those undergoing prolonged surgeries. Future studies should explore the optimal duration and method of preoxygenation to further enhance its effectiveness.

The effect of co-induction of fentanyl compared to oxycodone on anesthetic depth and hemodynamic status in surgical patients under general anesthesia at Prof. Ngoerah Denpasar General Hospital Tanggono, Aninda
Journal of Indonesia Vascular Access Vol. 5 No. 1 (2025): Available online : 1 June 2025
Publisher : Indonesian Vascular Access Association (IVAA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/jinava.v5i1.86

Introduction: Laryngoscopy and endotracheal intubation during general anesthesia can elicit sympathetic responses, including elevated blood pressure and heart rate. Fentanyl and oxycodone are opioids used for anesthesia co-induction to attenuate this response. This study aims to compare the co-induction effects of fentanyl and oxycodone on anesthesia depth and hemodynamic stability. Methods: This was a prospective observational study involving 40 adult patients with ASA I–II status undergoing general anesthesia at RSUP Prof. Ngoerah Denpasar. Subjects were randomized into two groups: fentanyl 2 µg/kg BW and oxycodone 0.2 mg/kg BW. All patients underwent standard induction protocols. The depth of anesthesia was assessed using the CONOX monitor (qCON), while hemodynamic status was evaluated through blood pressure, heart rate, and stroke volume via USCOM. Data were analyzed using t-tests and Mann-Whitney U tests with significance set at p<0.05. Results: There were no statistically significant differences in mean arterial pressure or heart rate between the groups (p>0.05), indicating similar hemodynamic responses. However, stroke volume reduction after intubation was significantly less in the oxycodone group (median ΔSV 3 vs 11.5; p<0.001). Additionally, qCON values showed better anesthesia depth with oxycodone (51.0 ± 5.8 vs 60.5 ± 7.5; p<0.001). Conclusion: Oxycodone co-induction results in better anesthesia depth and equal or superior hemodynamic stability compared to fentanyl. Oxycodone may be considered an effective alternative for co-induction in general anesthesia.

Effectiveness of a Community-Based First Aid Education Program on Choking for Laypersons in Surabaya, Indonesia: A Quasi-Experimental Study Tia Maya Affrita; Fitria Kusuma; Endang Susanti Warasanti; Tanggono, Aninda
Arkus Vol. 10 No. 3 (2024): Arkus
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/arkus.v10i3.617

Choking is a leading cause of accidental death, particularly among children and the elderly. Prompt first aid, especially the Heimlich maneuver, is crucial in preventing fatalities. This study aimed to evaluate the effectiveness of a community-based first aid education program on choking in Surabaya, Indonesia. A quasi-experimental, pre-post design was implemented in Surabaya. Participants were recruited from various community settings (workplaces and community centers). The intervention group received a comprehensive first aid education program on choking, while the control group received standard health education. Knowledge and skills related to choking first aid were assessed before and after the intervention. A total of 350 participants completed the study (175 per group). The intervention group demonstrated a significant improvement in knowledge (p < 0.001) and skills (p < 0.001) related to choking first aid compared to the control group. Additionally, the intervention group reported increased confidence in their ability to respond to choking emergencies. The community-based first aid education program significantly enhanced knowledge, skills, and confidence in choking first aid among laypersons in Surabaya. Such programs should be considered as a public health strategy to reduce choking-related morbidity and mortality.

Integrating Traditional Medicine into Mainstream Healthcare Systems: Challenges and Opportunities Cahya, Dini Aulia; Dewi, Riskha Dora Candra; Tanggono, Aninda; Hidayat, Rachmad
Riwayat: Educational Journal of History and Humanities Vol 8, No 2 (2025): April, Culture and Identity
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v8i2.45054

The integration of traditional medicine into mainstream healthcare systems presents both significant challenges and unique opportunities. This study employs a literature review methodology to examine the current landscape of traditional medicine practices and their potential role within conventional healthcare frameworks. By analyzing various studies, policy documents, and case reports, this paper identifies key barriers to integration, including regulatory issues, lack of standardization, and the prevailing skepticism among healthcare professionals. Additionally, it highlights the opportunities for enhanced patient care through a more holistic approach that combines the strengths of both traditional and modern medical practices. The findings suggest that successful integration requires collaborative efforts among stakeholders, including policymakers, healthcare providers, and traditional medicine practitioners. Furthermore, the study emphasizes the need for comprehensive training programs to educate healthcare professionals about traditional medicine and its benefits, as well as the establishment of regulatory frameworks to ensure safety and efficacy. This paper contributes to the growing discourse on healthcare integration by providing insights into the complexities of merging traditional and modern medical systems and offering recommendations for future research and policy development.

The Role of Technology in Enhancing Public Health Preparedness for Disasters Tanggono, Aninda; Prajnaparamita, Irfani; Nastaghfiruka, Prita Aulia
Riwayat: Educational Journal of History and Humanities Vol 8, No 2 (2025): April, Culture and Identity
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v8i2.44995

In recent years, the increasing frequency and severity of natural disasters have highlighted the critical need for enhanced public health preparedness. This literature review examines the role of technology in improving public health responses to disasters. Various technological advancements, including data analytics, geographic information systems (GIS), mobile applications, and telemedicine, have been identified as pivotal in enhancing preparedness and response efforts. Data analytics enables the timely collection and analysis of health information, facilitating informed decision-making during emergencies. GIS tools provide essential mapping capabilities that aid in resource allocation and risk assessment, allowing health officials to identify vulnerable populations and areas at high risk. Mobile applications enhance communication and information dissemination, ensuring that communities receive real-time updates and guidance during disasters. Furthermore, telemedicine has emerged as a vital tool for maintaining healthcare access when traditional services are disrupted. This review also discusses the challenges associated with technology integration, including issues of equity, privacy, and the need for training among healthcare professionals. Ultimately, the findings underscore the importance of leveraging technology to strengthen public health systems and improve disaster preparedness. By adopting innovative technological solutions, public health authorities can enhance their ability to respond effectively to disasters, ultimately safeguarding the health and well-being of communities.

The Effects of Lifestyle on The Incidence of Obesity Experienced by Many People: A Literature Review Azzahroh, Fitrotul Ainiyyah; Tanggono, Aninda
Journal of Diverse Medical Research: Medicosphere Vol. 1 No. 6 (2024): J Divers Med Res
Publisher : Faculty of Medical - UPN Veteran Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33005/jdiversemedres.v1i3.50

Obesity is a condition where a person's body exceeds normal weight due to the accumulation of excess body fat tissue. Obesity is caused by the amount of energy released by the body being less than the amount of food ingested. Someone who is obese can easily be measured using BMI. A person who has a BMI > 25.0 can be said to be overweight or obese (Nandar et al., 2019) in the journal Annurullah 2021. This literature aims to review the literature regarding the relationship between obesity and individual lifestyle patterns using a comparison of the best methods. The method used in this journal is by taking samples obtained from the BMI value index and using qualitative statistical methods. The resulting review of journal literature shows that obesity has a significant negative effect on exercise, physical activity and diet. Meanwhile, obesity has a significant positive effect on anxiety levels. It can be concluded that obesity is an abnormal condition in fat that can cause more serious health problems. Understanding the relationship between obesity and the factors that cause it really needs to be studied in more depth. In this journal method, it can be concluded that obesity has a positive and significant effect on exercise, physical activity and healthy diet, which means that the higher the physical activity, exercise and healthy diet, the lower the level of obesity.

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