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All Journal Majalah Kedokteran Gigi Indonesia Dental Journal (Majalah Kedokteran Gigi)
Hendrawan, Reza Dony
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Dentistry

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Development of a surgical guide using open-source software for a dental implant placement Mayasari, Dita Ayu; Kurniatie, Menik Dwi; Prasetyanto, Wisnu Adi; Fadhila, Shafa Salsa; Wicaksono, Bonifasius Primario; Hendrawan, Reza Dony
Majalah Kedokteran Gigi Indonesia Vol 11, No 1 (2025): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.96091

Abstract

Dental technology has advanced significantly in recent years, particularly with regard to the placement of dental implants to replace lost teeth. One such technology is the use of a dental implant guide as a tool to assist with implant installation. The primary purpose of a dental implant guide is to assist the dentist in placing implants with accuracy and precision to maximize operation success and minimize risk of problems. Dental implant guides customized to each patient’s unique tooth and jaw architecture are made possible in large part by digital dentistry. To ensure that the implant is positioned optimally in relation to the patient’s teeth and jaw anatomy, customization is important. Using the AutoDesk meshmixer for modeling and manufacturing, a 3D slicer to segment the mandible using a 3D segmentation approach and 3D printing using resin and filament are all part of the dental implant guide design process. To improve precision and customization in the placement of dental implants, this comprehensive strategy makes use of digital dentistry.
Induced pluripotent stem cells in periodontal reconstructive therapy: A narrative review of pre-clinical studies Hendrawan, Reza Dony; Prahasanti, Chiquita; Savitri, Irma Josefina; Hari, Padmini
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 4 (2023): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i4.p280-286

Abstract

Background: Regenerative periodontal surgical therapy faces significant challenges due to the limited ability of the body to regenerate damaged periodontal tissue. One of the primary goals in regenerative periodontal therapy is regaining periodontal tissue attachment after destruction by periodontal disease. Currently, stem cells, harnessing three pivotal components”cells, biomaterials, and growth factors”are widely used in periodontal regeneration. Stem cells can be obtained from various sources, either by isolating cells from bone marrow, teeth, and muscles or through the somatic cell programming method (reprogramming) known as induced pluripotent stem cells (iPSCs). Purpose: This review aims to describe the potential use of iPSCs in the treatment of periodontal defects. Review: Search strategies were developed using the PubMed, LILACS, Scielo, and Wiley online databases during the period of 2012–2022. Ten articles met the inclusion criteria. iPSCs were obtained by inducing somatic cells from both dental and non-dental sources with factors Oct3/4, Sox2, Klf4, and c-Myc. Periodontal tissue regeneration procedures can be augmented with iPSCs. Unlike tooth-based stem cells, iPSCs offer several advantages, such as unlimited cell sources and the capability to differentiate into any cell type, including periodontal tissue. The potential of iPSCs extends to correcting periodontal bone defects and forming new periodontal tissues, such as alveolar bone, cementum, and periodontal ligament. However, iPSCs do have limitations, including the need for clinical trials, cell programming production facilities, and optimization of differentiated-cell functionality. Conclusion: The combined use of iPSCs in cell-based tissue engineering holds vast potential for future periodontal treatment strategies.
Co-Authors Chiquita Prahasanti Dita Ayu Mayasari, Dita Ayu Fadhila, Shafa Salsa Hari, Padmini Irma Josefina Savitri Kurniatie, Menik Dwi Wicaksono, Bonifasius Primario Wisnu Adi Prasetyanto