Suryaman, Ine Suharyani
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The Development of Nano-mist Spray Propolis as Antioxidant Suryaman, Ine Suharyani; Sulastri, Lela; Rizikiyan, Yayan; Wathoni, Nasrul; Suhandi, Cecep; Noviani, Lusy; Rahmasari, Yuni
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.52433

Abstract

Propolis is a lipid-based compound from honeybees composed of plant wax, resin, and pollen. Due to its poor water solubility, its application is limited to lipid-based formulations with low bioavailability. This study aimed to develop a water-based propolis nano-mist spray with improved dispersion and evaluate its antioxidant activity. The nano-mist formulation was prepared using soy lecithin and Tween 80 in a phosphate buffer base. Evaluations included organoleptic characteristics, pH, particle size, zeta potential, and antioxidant activity by DPPH method. The propolis extract contained flavonoids, alkaloids, and tannins. The resulting spray showed a light brown color, a pH of 6.87 ± 0.03, particle size of 272.13 ± 4.25 nm, and zeta potential of -0.433 ± 0.35 mV. Antioxidant testing revealed moderate activity with an IC₅₀ value of 83.63 ± 11.88 ppm. This study supports the potential of nano-mist spray as a promising delivery system for propolis with antioxidant properties suitable for cosmetic and pharmaceutical applications.
Review: Isolation of Gelatin from Several Types of Fish Suryaman, Ine Suharyani; Sulastri, Lela; Astuti, Enih Nindi; Delviyanti, Elis; Senja, Rima Yulia; Tomi, Tomi
Indonesian Journal of Pharmaceutics Vol 7, Issue 1, Jan - April 2025
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v7i1.58575

Abstract

Indonesia is a country with the largest fishery waste, one of which is fish bones as a source of gelatin. Gelatin is the main protein that makes up skin and bone tissue in animals. This review was compiled to compare the results of isolating gelatin from bone waste in various types of fish. Articles were collected from the website https://scholar.google.co.id/ with "gelatin, gelatin content, gelatin in fish bones, viscosity, pH" in the 2015–2022 period, and 11 journals were obtained. In this literature study, a method for isolating gelatin from fish bone waste will be discussed, followed by an evaluation of the gelatin obtained, including its yield and its physical properties. It is hoped that the results of this review will provide information regarding a new source for gelatin isolation so that gelatin can be widely used by the food, pharmaceutical, cosmetic, and photographic industries, particularly in the pharmaceutical and food industries, which currently require gelatin as a stabilizer and emulsifier so that it can make and maintain the emulsion system.