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All Journal Journal of Innovative and Creativity
Musyaawarah, Yanti
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Education Languange, Linguistic, Communication & Media Mathematics Social Sciences Other

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Antibacterial Activity Test Of Ethanolic Extract Patch Preparations From Noni Leaves (Morinda Citrifolia L.) Using The Zone Of Inhibition Against Staphylococcus Aureus And Staphylococcus Epidermidis Bacteria Musyaawarah, Yanti; Suharyanisa, Suharyanisa; Marpaung, Jon Kenedy; Marpaung, Aditiya Baginda
Journal of Innovative and Creativity Vol. 5 No. 2 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i2.2060

Abstract

Wounds occur when there is damage or loss of body tissue due to factors that interfere with the body's protective system and cause infection caused by Staphylococcus aureus and Staphylococcus epidermidis.Noni leaf (Morinda citrifolia L.) has strong potential as an antibacterial, so researchers are interested in formulating ethanol extract of noni leaf (EEDM) into a patch preparation. Objective: Knowing that EEDM can be formulated as a patch preparation, as well as knowing its antibacterial activity. Methods: Four formulas were made with variations in extract concentration, namely F0 (blank); FI : 5%; FII: 10%; and FIII: 15%. Antibacterial testing using disc paper diffusion method. Results: A clear patch preparation was produced in F0, while in FI, FII and FIII the gel was blackish green with a distinctive smell of EEDM. The results of the antibacterial activity test against Staphylococcus aureus in each formula are FI: 2.58 mm; FII: 2.35 mm; FIII: 2.41 mm, while against Staphylococcus epidermidis, FI: 1.46; FII: 2.28; FIII: 3.33. Conclusion: EEDM can be formulated into patch preparations. The antibacterial potential of the three formulas is in the weak category.
Co-Authors Marpaung, Aditiya Baginda Marpaung, Jon Kenedy Suharyanisa