Tallo Manafe, Derri Riskiyanti
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Correlation of Age, Administration Method, and Amlodipine Dosage with the Risk of Side Effects in Hypertensive Patients Tarapanjang, Tiara Rambu Renesia; Riwu, Magdarita; Lada, Christina Olly; Tallo Manafe, Derri Riskiyanti
Cendana Medical Journal Vol 12 No 2 (2024): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v12i2.15537

Abstract

Hypertension, known as the "silent killer," poses a global threat with potentially fatal consequences. Lifelong treatment, often involving Amlodipine, requires careful management of age, dosage, and administration to mitigate side effects and enhance patients' quality of life. This study at RSUD Prof. Dr. W. Z. Johannes Kupang aimed to explore the correlation between age, Amlodipine dosage, and side effect risks. Utilizing an observational analytic method with a cross-sectional approach, data from 84 patients, aged 15-70, were collected between May and October 2023. Predominant side effects included edema (38.10%), dizziness (28.57%), fatigue (17.85%), and nausea (15.48%). Findings indicated age (p=0.013) and Amlodipine dosage (p=0.002) correlated with side effect risks. However, administration method analysis was hindered by consistent post-meal consumption in all participants. In conclusion, this research underscores the relevance of age and Amlodipine dosage in side effect risks for hypertensive patients. Practical implications include refined medication management strategies to improve overall patient well-being.
Hubungan Tingkat Kecemasan Dengan Kualitas Tidur Pasien Covid-19 di RSUD Prof. Dr. W. Z. Johannes Kupang latuperissa, alfonso jacobi; Lada, Christine Olly; Tallo Manafe, Derri Riskiyanti; Wungouw, Herman P.L.
Cendana Medical Journal Vol 14 No 1 (2026): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v14i1.13924

Abstract

Abstract Coronavirus Disease 2019 (COVID-19) is a contagious infectious disease that attacks the respiratory system caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). On March 11, 2020, WHO declared COVID-19 a pandemic and until October 14, 2022, 620 million confirmed cases, and of this 6 million people died (3). Generally, COVID-19 patients isolated in hospitals have higher levels of anxiety and somatization symptoms because patients think negative things so that patients become pessimistic. The immune system of COVID-19 patients is a major factor in the healing process. The anxiety experienced by the patient causes a lack of rest and a decrease in the quality of the patient's sleep (12). The condition of the COVID-19 pandemic tends to have a negative impact on several factors that affect a person's sleep quality so that researchers are interested in further researching the relationship between anxiety levels and sleep quality, especially in COVID-19 patients at Hospital Prof. Dr. W Z Johannes Kupang. This study is a retrospective analytic study using a cross-sectional approach. The sampling technique in this study used a purposive sampling technique with the aim of taking samples according to the inclusion criteria. The sample in this study was determined using a formula to test the correlation coefficient so that a sample size of 50 respondents was obtained. Where the analysis used in this study uses the Spearman rank test. From 50 respondents, 27 respondents (54%) experienced moderate anxiety and 42 respondents (84%) had poor sleep quality. Spearman rank test results obtained p = 0.000 and the value of r = 0.546.There is a significant relationship between anxiety levels and sleep quality of COVID-19 patients at Hospital Prof. Dr. W Z Johannes Kupang. Keywords: COVID-19, Anxiety, Sleep Quality, COVID-19 Patients