Article Per Year (5 Year)
p-Index From 2021 - 2026
0.778
P-Index
This Author published in this journals
All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Health and Medical Journal Cermin Dunia Kedokteran
Pramudita, Adelia Wuri
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Exploring the clinical studies of surgical acne scar management: a 10-year systematic review of modalities and outcomes Pramudita, Adelia Wuri; Asaduddin, Aiman Hilmi
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2025): June 2025
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v%vi%i.34560

Abstract

Acne scars are permanent sequelae of acne vulgaris, classified into hypertrophic, keloid, and atrophic types. Treatment strategies include non-invasive, minimally invasive, and invasive modalities. This systematic review evaluates clinical studies from the past decade on surgical and related interventions for acne scars. Using PRISMA guidelines, searches were conducted on PubMed, Scopus, and Epistemonikos with keywords related to "acne scar" and "surgical therapy." Twenty-four studies met the inclusion criteria out of 396 screened articles. The modalities examined encompass TCA CROSS, radiofrequency (RF) micro-needling, fractional microplasma RF, fractional bipolar RF, fractional CO₂ laser, erbium YAG (2940 nm), 1550 nm erbium, 1540 nm erbium glass, subcision, punch techniques, microdermabrasion, needling, platelet-rich plasma (PRP), hyaluronic acid fillers, hybrid energy devices, trifractional technology, and human adipose-derived stem cell exosomes (ASCE). Results demonstrated variable efficacy, with predominantly positive outcomes across modalities. Specific treatments showed better suitability for certain scar types; however, all carry potential risks of adverse effects, emphasizing the need for cautious application and patient management. Limitations include small sample sizes and heterogeneity among studies, which may affect the generalizability of findings. This review highlights the diversity of surgical and minimally invasive options for acne scar management, supporting tailored treatment approaches based on scar morphology and patient factors.
Korelasi Kadar Vitamin D Serum dan Derajat Keparahan Psoriasis Vulgaris Berdasarkan Skor PASI dan DLQI Pramudita, Adelia Wuri; Mulianto, Nur M Rachmat; Evanti, Annisa Marsha; Widyastuti, Zilpa; Asaduddin, Aiman Hilmi
Health and Medical Journal Vol 6, No 2 (2024): HEME May 2024
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v6i2.1476

Abstract

Latar Belakang: Derajat keparahan psoriasis vulgaris ditentukan berdasarkan skor Psoriasis Area and Severity Index (PASI) dan Dermatology Life Quality Index (DLQI). Perjalanan psoriasis dapat dipengaruhi oleh abnormalitas sistem imun, kerentanan genetik, lingkungan dan gaya hidup. Vitamin D juga diduga berperan pada perjalanan berbagai penyakit autoimun termasuk psoriasis. Tujuan: Untuk mengetahui korelasi antara kadar vitamin D serum dengan derajat keparahan psoriasis vulgaris berdasarkan skor  PASI dan DLQI. Metode: Penelitian ini merupakan penelitian analitik eksperimental terhadap 10 subjek dan dilakukan pengukuran kadar vitamin D serum dengan metode Enzyme Linked Immunosorbent Assay (ELISA). Data klinis dan derajat keparahan psoriasis vulgaris dilakukan dengan skoring PASI dan DLQI. Data dianalisis secara deskriptif dan disajikan dalam tabel distribusi frekuensi. Pengolahan data menggunakan uji statistik Spearman untuk menilai korelasi antara kadar vitamin D serum dengan derajat keparahan psoriasis vulgaris berdasarkan skor PASI dan DLQI. Hasil: Analisis data menunjukkan tidak ada korelasi antara kadar vitamin D serum dengan derajat keparahan psoriasis vulgaris berdasarkan PASI (nilai p=0,751 dan koefisien korelasi r=-0,116) dan berdasarkan skor DLQI (nilai p=0,751 dan koefisien korelasi r=-0,116). Kesimpulan: Kadar vitamin D serum tidak berkorelasi dengan derajat keparahan psoriasis vulgaris.
Eritema Nodosum Leprosum Berat pada Pasien Kusta Lepromatosa: Laporan Kasus Pramudita, Adelia Wuri; Kariosentono, Harijono; Evanti, Annisa Marsha; Asaduddin, Aiman Hilmi
Cermin Dunia Kedokteran Vol 51 No 12 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i12.1116

Abstract

A case of a 58-year-old woman with lepromatous leprosy and severe ENL reaction is reported. The patient has symptoms of pustules for 1 year and the nodules were getting worse in the last week, accompanied by fever, joint pain, nausea, and vomiting. Physical examination revealed madarosis, infiltrates of both ears, and multiple painful erythematous nodules on the extremities and trunk. Slit skin smear examination showed bacterial index +3 and morphological index of 15%. Histopathological examination revealed neutrophil infiltration and vasculitis in the upper dermis. The patient was diagnosed with lepromatous leprosy and severe ENL reaction. The patient received multidrug therapy and methylprednisolone (62.5 mg/day), which was gradually reduced. The ENL reaction is caused by the deposition of M. leprae antigens and antibodies in small blood vessels, resulting in vasculitis and the release of enzymes that damage tissues. ENL reactions are commonly found in multibacillary MH and occur before, during, and after treatment. This reaction is mediated by cytokines produced by T-helper-2 (Th2). ENL reactions can cause disability.
Mekanisme Pertahanan Mukokutan terhadap Infeksi Candida: Analisis Pramudita, Adelia Wuri; Kariosentono, Harijono; Evanti, Annisa Marsha; Widyastuti, Zilpa
Cermin Dunia Kedokteran Vol 52 No 3 (2025): Oftalmologi dan Dermatologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i3.1157

Abstract

Candida albicans is a commensal organism that can may become invasive and fatal under certain circumstances. Several genetic variations in the human genome towards susceptibility to Candida infections have been identified. There are a number of genes associated with Candida virulence factors, host environment, and immune response. C-type lectin receptors (CLRs) are characterized by leucine-rich and nucleotidebinding domains that can detect intracellular signals through various types of cytoplasmic domains. CLRs are family of PRRs that bind glycan through recognition of extracellular carbohydrate and mediate intracellular signaling through various type of cellular domains, resulting in a decrease of neutrophils and facilitating the occurrence of fungal infections. This study review the genetic determinant of defense mechanisms and immune deficiencies against Candida infection.
Co-Authors Annisa Marsha Evanti Asaduddin, Aiman Hilmi Kariosentono, Harijono Mulianto, Nur M Rachmat Widyastuti, Zilpa