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All Journal Jurnal Farmamedika (Pharmamedica Journal) Jurnal Farmasi
Nur Rahmawati, Aulia
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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PENENTUAN NILAI SUN PROTECTION FACTOR (SPF) FRAKSI DAUN MURBEI (Morus alba L) SEBAGAI TABIR SURYA Saryanti, Dwi; Nur Rahmawati, Aulia; Utami , Nastiti; Putri Atmaja, Aulia
Jurnal Farmamedika (Pharmamedika Journal) Vol 10 No 1 (2025): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v10i1.354

Abstract

Nilai Sun Protection Factor (SPF) merupakan salah satu indikator kefektifan suatu produk dalam menangkal sinar UV. Daun murbei mempunyai kandungan flavonoid, alkaloid, tanin, saponin dan steroid. Flavonoid dapat digunakan sebagai pelindung kulit karena adanya gugus kromofor sehingga mampu menangkal radiasi UV A serta UV B sehingga mereduksi paparan di permukaan kulit manusia dapat direduksi. Penelitian yang dilakukan mempunyai maksud untuk menentukan nilai SPF fraksi air, etil asetat dan n-heksana daun murbei. Daun murbei dimaserasi dengan pelarut etanol 96%, kemudian diekstraksi menggunakan air, etil asetat dan n-heksana. Nilai SPF ditentukan secara in vitro dengan metode spektrofotometri UV. Hasil penelitian diperoleh fraksi etil asetatmempunyai nilai SPF tertinggi sebesar 37,224. Nilai SPF pada fraksi air dan n-heksana daun murbei sebesar 31,276 dan 17,002. Nilai SPF pada fraksi etil asetat dan air daun murbei termasuk kategori tinggi (30-50) dan pada fraksi n-heksana termasuk kategori sedang (15-30).
Formulasi Nanoemulgel Peel Off Ekstrak Buah Stroberi (Fragaria x ananassa) dan Minyak Palmarosa (Cymbopogon martinii) Sebagai Antibakteri Propionibacterium acnes Sundari, Pungky; Puspitasari, Dian; Nur Rahmawati, Aulia
Jurnal Farmasi (Journal of Pharmacy) Vol. 13 No. 2 (2024): Jurnal Farmasi (Journal of Pharmacy), October 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/c2q54s10

Abstract

Acne is an inflammatory skin disorder that is mostly caused by Propionibacterium acnes. Secondary metabolites such as saponins, tannins, and flavonoids in strawberries and geraniol in Palmarosa oil can function as antibacterials. To produce a more durable product and increase the solubility of Palmarosa oil, a formula was developed in the form of a nanoemulgel peel-off mask because it is easy to apply to the skin, the active ingredient is quickly penetrated, and increases the stability of the active ingredient. The research aims to determine the effect of different concentrations of strawberry fruit extract on the physical properties and antibacterial activity of the test preparation against Propionibacterium acnes. The nanoemulgel peel-off mask was formulated in 3 different concentrations of strawberry fruit extract, namely F1 = 3%, F2 = 4%, and F3 = 5%. The nanoemulgel peel-off mask preparation was made by inserting nanoemulsion into the gel. The test evaluation included the % transmittance test, nanoemulsion type, pH, organoleptic, homogeneity, adhesion, spreadability, viscosity, drying time, and Propionibacterium acnes antibacterial activity test. The results showed that the difference in concentration of Strawberry fruit extract in the nanoemulgel peel off mask preparation had a significant effect on the results of pH, viscosity, spreadability, and adhesion tests, but did not have a significant effect on the results of the Propionibacterium acnes antibacterial activity test. The concentration of 5% Strawberry fruit extract in formula 3 had the best physical properties of the preparation and the greatest antibacterial activity of Propionibacterium acnes compared to other formulas with an inhibition zone value of 12.19 ± 0.70 mm.
Co-Authors Dian Puspitasari Putri Atmaja, Aulia Saryanti, Dwi Sundari, Pungky Utami , Nastiti