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All Journal Sainstech Farma: Jurnal Ilmu Kefarmasian Soeropati: Journal of Community Service Jurnal Farmasi dan Sains Indonesia (JFSI)
Arianti, Anisa Rachmita
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Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Training on Making and Testing the Efficacy of Hand Sanitizers from Lime and Sweet Orange Essential Oils for Pharmacy Students at Al-Muhtadin Vocational School Bekasi, West Java, Indonesia Anindita, Reza; Putri, Intan Kurnia; Beandrade, Maya Uzia; Arianti, Anisa Rachmita; Futihat, Chilyati Eky
Jurnal Soeropati Vol 7 No 2: May 2025
Publisher : LPPM Universitas Yudharta Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35891/js.v7i2.6124

Abstract

Community analysis shows that Al-Muhtadin Pharmacy Vocational School, Bekasi students are interested in making pharmaceutical products from natural ingredients. However, their desires are often hampered by the lack of knowledge regarding manufacturing pharmaceutical preparations from natural ingredients. Therefore, the solution is to hold training in hand sanitizers with natural ingredients from essential oils of lime and sweet orange peels. This Community Service activity (CSA) aims to provide training in making and testing hand sanitizers for Al-Muhtadin Pharmacy Vocational School students in Bekasi. The CSA participants numbered 62 students of Al-Muhtadin Pharmacy Vocational School, Bekasi. The activity methods include providing material on Clean and Healthy Living Behavior (CHLB) and making hand sanitizers, training in making and testing hand sanitizer products, and evaluation in the form of concept tests (pre-test and post-test) and skills tests. The paired t-test results showed that the calculated t-value was smaller than the t-table (-4.952 <-2.013), or there was a significant difference in the average value of knowledge about CHLB and making hand sanitizers between before and after being given the material. In contrast, the practical exam showed the average percentage value of participants' skills in making hand sanitizers of 90.57%, while the efficacy testing skills were 93.44%. Testing of the antibacterial efficacy of hand sanitizer products by respondents showed that they were able to inhibit and kill bacteria on the hands. This CSA concludes that all participants have learned the concept and skills regarding manufacturing and testing hand sanitizers from a combination of lime and sweet orange peel essential oils.
Efek Samping Obat Antituberkulosis (OAT) Lini Pertama pada Penderita TB Paru di Puskesmas X Kota Bekasi Periode Januari–Maret 2025 Kamila, Aulia Salasa; Futihat, Chilyati Eky; Arianti, Anisa Rachmita; ., Maifitrianti
Sainstech Farma: Jurnal Ilmu Kefarmasian Vol 18 No 2 (2025): Sainstech Farma: Jurnal Ilmu Kefarmasian
Publisher : LPPM, INSTITUT SAINS DAN TEKNOLOGI NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37277/sfj.v18i2.2354

Abstract

Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis. This disease is still a health problem in the world. The most widely used therapy is First-line OAT. The use of this drug can cause side effects of the drug. The purpose of this study was to determine the side effects of using first-line OAT therapy drugs. This type of study is descriptive observational with a cross-sectional study design. The sampling technique used was consecutive sampling. with inclusion criteria of patients receiving first-line OAT treatment, aged 20-65 years old, patients with intensive or advanced treatment stages, patients with 1 week of treatment then the causality of drug side effects was analyzed using the naranjo algorithm. This study had a sample of 39 respondents who met the inclusion criteria, 62% male patients and 36% aged 20-29 years. As many as 56% were in the intensive treatment phase with the longest treatment duration being 1 month (26%). During the use of first-line OAT, 54% complained of nausea and vomiting, 18% joint pain, 56% red urine, 21% loss of appetite. The results of the causality analysis using the naranjo algorithm showed that the side effects experienced were included in the probable category. The use of first-line OAT in patients with pulmonary tuberculosis can cause side effects. This is stated using the causality analysis of the naranjo algorithm, showing a score of 5-8 (probable) which means the possibility of ESO due to the use of first-line OAT.
Pengaruh Pemberian Antipsikotik terhadap Sindrom Metabolik pada Pasien Skizofrenia di Rumah Sakit X Jakarta Periode Juli 2023 – Desember 2023 Anggraeni, Vivi; Futihat, Chilyati Eky; Arianti, Anisa Rachmita; Perwitasari, Melania
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p81-94

Abstract

Schizophrenia is a severe mental disorder requiring long-term treatment with antipsychotics. Although effective in managing psychotic symptoms, antipsychotics such as Haloperidol (first-generation) and Clozapine (second-generation) carry risks of inducing metabolic syndrome, particularly hypertension and obesity. This study aims to compare the effects of Haloperidol and Clozapine use on the incidence of metabolic syndrome, specifically hypertension and obesity, in schizophrenia patients based on the 2021 PERKENI criteria. This analytical non-experimental study used a cross-sectional design with retrospective data from medical records of inpatient schizophrenia patients at X Regional Special Hospital Jakarta from July–December 2023. A total of 95 patients were selected by purposive sampling. Data were analyzed using the Mann-Whitney test. The majority of patients were male (56 patients, 58.95%) and aged 31–50 years (44 patients, 46.32%). Haloperidol was used by 50 patients (52.63%), while Clozapine was used by 45 patients (47.37%). The medication was administered orally as a single agent, 1–3 times daily, with doses ranging from 0.5 mg to 100 mg and an average treatment duration of 30 days. Total drug administrations were recorded 133 times due to some patients receiving more than one dosage form (tablet and single compound). Metabolic syndrome was observed in 40 patients (42.11%). Haloperidol significantly increased blood pressure compared to Clozapine (p = 0.036), but no significant difference was found in body mass index (p = 0.885). Haloperidol poses a higher risk of inducing hypertension than Clozapine. Routine blood pressure monitoring is essential during therapy.
Pengaruh Penggunaan Obat Khelasi Besi Terhadap Perubahan Kadar Ferritin Serum Pada Pasien Thalasemia Di Rumah Sakit Umum Daerah “X” Kota Bekasi Agustiani, Elsya; Futihat, Chilyati Eky; Arianti, Anisa Rachmita; Maifitrianti, Maifitrianti
Jurnal Farmasi & Sains Indonesia Vol 8 No 2 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no2p57-65

Abstract

Thalassemia is a blood disorder that is inherited from both parents to their children. Ferritin levels are often elevated due to repeated blood transfusions that cause iron buildup in the body, leading to serious complications if not treated with iron chelation therapy. Iron chelation is a therapeutic method to reduce excessive iron levels in the body that is not bound in plasma and excreted from the body. To see the effect of using iron chelation drugs on reducing serum ferritin levels in patients with thalassemia beta major. Analytical observational research with a retrospective cross-sectional study design using limited secondary medical record data. The sampling technique used consecutive sampling with the inclusion criteria of beta major thalassemia patients with serum ferritin levels ≥1000ng/mL who received a single iron chelation therapy treatment. The effect of iron chelation drug administration in beta major thalassemia patients on reducing serum ferritin levels was analyzed using the Wilcoxon Signed-Ranks Test. In this study, 50 patients met the inclusion criteria. 52% of patients were female, and 40% had an age range of 0-5 years. The most common single iron chelation drug was Deferasirox (85%), with a dose of 250 mg (49%). A total of 6% of patients had decreased serum ferritin levels (≥500ng/mL and <1000ng/mL). However, the results of the data analysis showed that there was no significant decrease in serum ferritin levels after single iron chelation. This study showed that single iron chelation therapy was effective in reducing serum ferritin levels, but not significant (p value>0.05).
Co-Authors ., Maifitrianti Agustiani, Elsya Anggraeni, vivi Beandrade, Maya Uzia Futihat, Chilyati Eky Kamila, Aulia Salasa Maifitrianti Maifitrianti, Maifitrianti Melania Perwitasari, Melania Putri, Intan Kurnia