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All Journal Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Sainstech Farma: Jurnal Ilmu Kefarmasian Soeropati: Journal of Community Service Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Buana Farma
Futihat, Chilyati Eky
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Botanical, Pharmacognosy, and Phytochemical Studies of Sintrong Leaves (Crassocephalum crepidioides) Growing in Tanjung Setia Village, West Coast, Lampung: Kajian Botani, Farmakognosi, dan Fitokimia Daun Sintrong (Crassocephalum crepidioides) yang Tumbuh di Desa Tanjung Setia Pesisir Barat Lampung Anindita, Reza; Pratama, Gita Cahya; Putri, Intan Kurnia; Beandrade, Maya Uzia; Futihat, Chilyati Eky
Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Vol. 12 No. 1 (2025)
Publisher : Department of Biology Faculty of Mathematics and Natural Sciences Universitas Lampung in collaboration with The Indonesian Association of Biology (PBI) Lampung Branch.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jbekh.v12i1.423

Abstract

Crassochepalum crepidioides plant has antibacterial and anti-wound properties. This study aims to determine the botanical profile, microscopic powder, phytochemical screening, and Thin Layer Chromatography (TLC). This study aims to determine the morphology of leaves, stems, roots, microscopic powder, phytochemical screening, and Thin Layer Chromatography (TLC) of C. crepidioides leaves from Tanjung Setia Village West Coast Lampung, Indonesia. Methods include morphological examination, microscopic powder, phytochemical screening, and TLC. The results of the botanical show oval-shaped leaves, pointed tips, pinnate veins, serrated edges, smooth leaf surface, soft wood stems, and tap roots. Microscopic observation found fragments of stomata. Positive phytochemical screening of alkaloids, flavonoids, saponins, and tannins. TLC test spot with five spots (red) and an average Rf value of 0.21-0.97. Concludes that the thin layer chromatography test is thought to produce flavonoid spots at an Rf value of 0.72-0.77.
Training on Making and Testing the Efficacy of Hand Sanitizers from Lime and Sweet Orange Essential Oils for Pharmacy Students at Al-Muhtadin Vocational School Bekasi, West Java, Indonesia Anindita, Reza; Putri, Intan Kurnia; Beandrade, Maya Uzia; Arianti, Anisa Rachmita; Futihat, Chilyati Eky
Jurnal Soeropati Vol 7 No 2: May 2025
Publisher : LPPM Universitas Yudharta Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35891/js.v7i2.6124

Abstract

Community analysis shows that Al-Muhtadin Pharmacy Vocational School, Bekasi students are interested in making pharmaceutical products from natural ingredients. However, their desires are often hampered by the lack of knowledge regarding manufacturing pharmaceutical preparations from natural ingredients. Therefore, the solution is to hold training in hand sanitizers with natural ingredients from essential oils of lime and sweet orange peels. This Community Service activity (CSA) aims to provide training in making and testing hand sanitizers for Al-Muhtadin Pharmacy Vocational School students in Bekasi. The CSA participants numbered 62 students of Al-Muhtadin Pharmacy Vocational School, Bekasi. The activity methods include providing material on Clean and Healthy Living Behavior (CHLB) and making hand sanitizers, training in making and testing hand sanitizer products, and evaluation in the form of concept tests (pre-test and post-test) and skills tests. The paired t-test results showed that the calculated t-value was smaller than the t-table (-4.952 <-2.013), or there was a significant difference in the average value of knowledge about CHLB and making hand sanitizers between before and after being given the material. In contrast, the practical exam showed the average percentage value of participants' skills in making hand sanitizers of 90.57%, while the efficacy testing skills were 93.44%. Testing of the antibacterial efficacy of hand sanitizer products by respondents showed that they were able to inhibit and kill bacteria on the hands. This CSA concludes that all participants have learned the concept and skills regarding manufacturing and testing hand sanitizers from a combination of lime and sweet orange peel essential oils.
Efek Samping Obat Antituberkulosis (OAT) Lini Pertama pada Penderita TB Paru di Puskesmas X Kota Bekasi Periode Januari–Maret 2025 Kamila, Aulia Salasa; Futihat, Chilyati Eky; Arianti, Anisa Rachmita; ., Maifitrianti
Sainstech Farma: Jurnal Ilmu Kefarmasian Vol 18 No 2 (2025): Sainstech Farma: Jurnal Ilmu Kefarmasian
Publisher : LPPM, INSTITUT SAINS DAN TEKNOLOGI NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37277/sfj.v18i2.2354

Abstract

Tuberculosis is a disease caused by the bacteria Mycobacterium tuberculosis. This disease is still a health problem in the world. The most widely used therapy is First-line OAT. The use of this drug can cause side effects of the drug. The purpose of this study was to determine the side effects of using first-line OAT therapy drugs. This type of study is descriptive observational with a cross-sectional study design. The sampling technique used was consecutive sampling. with inclusion criteria of patients receiving first-line OAT treatment, aged 20-65 years old, patients with intensive or advanced treatment stages, patients with 1 week of treatment then the causality of drug side effects was analyzed using the naranjo algorithm. This study had a sample of 39 respondents who met the inclusion criteria, 62% male patients and 36% aged 20-29 years. As many as 56% were in the intensive treatment phase with the longest treatment duration being 1 month (26%). During the use of first-line OAT, 54% complained of nausea and vomiting, 18% joint pain, 56% red urine, 21% loss of appetite. The results of the causality analysis using the naranjo algorithm showed that the side effects experienced were included in the probable category. The use of first-line OAT in patients with pulmonary tuberculosis can cause side effects. This is stated using the causality analysis of the naranjo algorithm, showing a score of 5-8 (probable) which means the possibility of ESO due to the use of first-line OAT.
Pengaruh Pemberian Antipsikotik terhadap Sindrom Metabolik pada Pasien Skizofrenia di Rumah Sakit X Jakarta Periode Juli 2023 – Desember 2023 Anggraeni, Vivi; Futihat, Chilyati Eky; Arianti, Anisa Rachmita; Perwitasari, Melania
Jurnal Farmasi & Sains Indonesia Vol 8 No 1 (2025)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol8no1p81-94

Abstract

Schizophrenia is a severe mental disorder requiring long-term treatment with antipsychotics. Although effective in managing psychotic symptoms, antipsychotics such as Haloperidol (first-generation) and Clozapine (second-generation) carry risks of inducing metabolic syndrome, particularly hypertension and obesity. This study aims to compare the effects of Haloperidol and Clozapine use on the incidence of metabolic syndrome, specifically hypertension and obesity, in schizophrenia patients based on the 2021 PERKENI criteria. This analytical non-experimental study used a cross-sectional design with retrospective data from medical records of inpatient schizophrenia patients at X Regional Special Hospital Jakarta from July–December 2023. A total of 95 patients were selected by purposive sampling. Data were analyzed using the Mann-Whitney test. The majority of patients were male (56 patients, 58.95%) and aged 31–50 years (44 patients, 46.32%). Haloperidol was used by 50 patients (52.63%), while Clozapine was used by 45 patients (47.37%). The medication was administered orally as a single agent, 1–3 times daily, with doses ranging from 0.5 mg to 100 mg and an average treatment duration of 30 days. Total drug administrations were recorded 133 times due to some patients receiving more than one dosage form (tablet and single compound). Metabolic syndrome was observed in 40 patients (42.11%). Haloperidol significantly increased blood pressure compared to Clozapine (p = 0.036), but no significant difference was found in body mass index (p = 0.885). Haloperidol poses a higher risk of inducing hypertension than Clozapine. Routine blood pressure monitoring is essential during therapy.
EFEK PENGGUNAAN BETA BLOCKER TERHADAP KEJADIAN HIPOGLIKEMIA PADA LANSIA: NARRATIVE REVIEW Adisaputra, Arya Dibyo; Susilawati, Ni Made; Fatkhiya, Musa Fitri; Gibran, Nabial Chiekal; Futihat, Chilyati Eky
Jurnal Buana Farma Vol. 5 No. 3 (2025): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i3.1501

Abstract

Elderly patients are considered a vulnerable population, as advanced age may exacerbate existing conditions or predispose individuals to adverse effects such as hypoglycemia. While hypoglycemia most frequently occurs in patients with diabetes who are treated with insulin or oral hypoglycemic agents, it may also develop in non-diabetic individuals under certain circumstances. The use of beta-blockers has been identified as one potential contributing factor to hypoglycemic events. This article aims to review the adverse effects of beta-blocker therapy in relation to hypoglycemia among older adults. A narrative review was conducted through electronic databases including PubMed, Google Scholar, and ScienceDirect. The inclusion criteria were studies published within the last 10 years involving older patients who experienced hypoglycemia while receiving beta-blocker therapy. The search yielded 38 articles, of which only 4 met the inclusion criteria. In conclusion, the use of β-blockers appears to be associated with an increased risk of severe hypoglycemia; however, evidence specifically addressing the geriatric population remains limited.
Co-Authors ., Maifitrianti Adisaputra, Arya Dibyo Anggraeni, vivi Arianti, Anisa Rachmita Beandrade, Maya Uzia Fatkhiya, Musa Fitri Gibran, Nabial Chiekal Kamila, Aulia Salasa Melania Perwitasari, Melania Ni Made Susilawati Pratama, Gita Cahya Putri, Intan Kurnia