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All Journal Svāsthya: Trends in General Medicine and Public Health
Machado, Filipe de Neri
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Spatial risk assessment of canine rabies transmission via GIS buffer analysis in Bobonaro municipality, Timor-Leste Cruz, Zito Viegas da; Pereira, Abrão J.; Machado, Filipe de Neri; Adnyana , I Made Dwi Mertha; Jundaeng, Jarupat
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 4 (2025): July 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i4.137

Abstract

Rabies is a fatal zoonotic disease caused by Lyssavirus of the Rhabdoviridae family. Timor-Leste experienced a rabies outbreak in March 2024, with a 100% fatality rate, primarily affecting dogs as the main reservoir. Bobonaro Municipality has reported an increasing number of confirmed cases, necessitating spatial approaches for effective control strategies. This study aimed to identify confirmed rabies case distribution patterns and predict transmission risk zones via GIS buffer analysis within the Bobonaro Municipality. This study utilized secondary data from 39 confirmed rabies cases from the Bobonaro Municipal Agriculture Service between January and June 2025. The analysis was conducted via the Buffer and Multiple Buffer tools in ArcGIS 10.8 software. The geographic coordinates of confirmed cases were mapped to generate distribution maps with transmission movement predictions on the basis of locations in each administrative post, village, and hamlet. Mapping revealed that the majority of confirmed rabies cases were concentrated in the northeastern Bobonaro Municipality, comprising the Cailaco administrative post with the hamlets of the Meligo village, such as Bereleu, Daulelo, Liabote, and Mude, plus the Maliana administrative post. Buffer analysis with a 2 km radius identified tendencies for animal movement at risk of local rabies transmission that could spread to humans and other animals, including neighboring municipalities sharing land borders with Bobonaro. GIS-based buffer analysis successfully identified high-risk zones for rabies transmission within a 2 km radius of the average confirmed case locations. These findings provide an evidence-based foundation for policymakers to implement effective and specific rabies control strategies tailored to Timor-Leste's resource-limited environment.
Risk factors for loss to follow-up in HIV care: A retrospective cohort study in Dili, Timor-Leste Amaral, Benigna Veneranda da Costa Amaral; Yeom, Joon Sup; Machado, Filipe de Neri; Marques, Mariano da Silva; Soares, Noel Gama
Svāsthya: Trends in General Medicine and Public Health Vol. 2 No. 5 (2025): September 2025
Publisher : PT. Mega Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70347/svsthya.v2i5.141

Abstract

Loss to follow-up (LTFU) among people living with HIV/AIDS (PLWHA) is a public health challenge that reduces the effectiveness of antiretroviral therapy (ART), increases the risk of transmission, and contributes to increased mortality. This study aimed to identify the risk factors for LTFU among patients with HIV in Dili, Timor-Leste. This retrospective cohort study used secondary data from 150 HIV-positive patients at the Community Progress Association (AK-P) in Dili from 2014 to 2022. The inclusion criterion was adult patients aged ≥ 15 years who started ART with a minimum follow-up of 183 days. Descriptive statistics, chi-square tests, logistic regression, and Kaplan‒Meier analysis were used to identify the factors affecting LTFU. Of the 150 patients, 72% remained under care, 20.6% experienced LTFU, and 7.3% died. The majority were male (90%), with men who had sex with men (MSM) having a 40% lower risk of LTFU than female sex workers (FSW). Patients aged ≥54 years had a 21% lower risk, and married individuals had a 26% lower risk than single individuals did. High income and ART initiation were protective factors, while a CD4 count <200 cells/mm³ increased the risk of LTFU by 4.2 times, and a viral load >1000 copies/mL increased the risk by 2.79 times. Level 1 ART was associated with 97% survival at 1, 3, and 5 years, whereas level 2 ART was associated with only 3.6% survival in the first year. Sociodemographic and clinical variables influenced LTFU in HIV care in Timor-Leste. 
Co-Authors Adnyana , I Made Dwi Mertha Amaral, Benigna Veneranda da Costa Amaral Cruz, Zito Viegas da Jundaeng, Jarupat Marques, Mariano da Silva Pereira, Abrão J. Soares, Noel Gama Yeom, Joon Sup