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All Journal Jurnal Kesehatan Ibu dan Anak Jurnal Kesehatan Masyarakat
Wijayanti , Siwi Pramatama Mars
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Education Health Professions Medicine & Pharmacology Nursing Public Health

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The risk and obstetric outcomes of preeclampsia in pregnancies with non-ideal maternal age: a systematic review Azizah; Wijayanti , Siwi Pramatama Mars; Rejeki, Dwi Sarwani Sri
Jurnal Kesehatan Ibu dan Anak Vol. 18 No. 2
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/kia.v18i2.2805

Abstract

Preeclampsia remains a leading cause of maternal and neonatal morbidity, with increased risk observed at both extremes of maternal age adolescents (<20 years) and women of advanced maternal age (>35 years). However, the comparative obstetric impacts of preeclampsia across these age groups remain underexplored in a structured synthesis. This study aims to provide an up-to-date, evidence-based understanding to support maternal health policy planning, clinical obstetrics, and reproductive education tailored to high-risk populations. This systematic review was conducted following PRISMA guidelines. Electronic databases including PubMed, Scopus, and Google Scholar were searched for peer-reviewed studies published between 2015 and 2025. Studies were eligible if they reported preeclampsia prevalence and obstetric outcomes among pregnant individuals aged <20 or >35 years. Seven observational and cohort studies met the inclusion criteria. Adolescent pregnancies complicated by preeclampsia showed high cesarean section rates (82.9% in those aged ?16 and 89.3% in ages 17–19), and increased risk of anemia and pregnancy complications despite comparable neonatal outcomes across age subgroups. In contrast, advanced maternal age was associated with a higher prevalence of severe preeclampsia (68.9%), eclampsia (12.3%), HELLP syndrome (8.7%), and emergency cesarean delivery (71.3%). Neonatal complications included low birth weight (34.4%) and lower five-minute Apgar scores. Use of assisted reproductive technologies in women ?40 further amplified the risk of early-onset preeclampsia and prematurity. Pregnancies at non-ideal maternal ages carry distinct pathophysiological risks and result in increased obstetric complexity and need for medical intervention. Age-specific clinical approaches such as early screening, targeted antenatal education, and enhanced maternal-fetal surveillance are essential. These findings support maternal health policies that incorporate maternal age as a key determinant for individualized risk assessment and care planning.
Unsuccessful Drug-Resistant TB Treatment Outcomes among Patients with Short-Term Regimen in Central Java, Indonesia Ardiani, Intan Henda; Rejeki, Dwi Sarwani Sri; Wijayanti , Siwi Pramatama Mars; Saefurrohim, Muhamad Zakki
Jurnal Kesehatan Masyarakat Vol. 20 No. 4 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v20i4.9483

Abstract

Tuberculosis which shows resistance to various types of drugs poses a significant burden in efforts to prevent and control tuberculosis globally. Since 2020, guidelines from the WHO have recommended a shorter treatment with an all-oral regimen for Drug Resistant Tuberculosis (DR-TB), with the inclusion of bedaquiline instead of an injectable agent. However, the treatment success rate for DR-TB in Indonesia is still low. This study aimed to determine factors contributing to unsuccessful DR-TB treatment using STR in Central Java. This was a nested case-control study of 412 DR-TB patients enrolled with a Short-Term Regimen, registered in 2021 to 2023 who had treatment results in a subset of the Tuberculosis Information System cohort data. Independent variables analyzed included age, gender, patient employment status, history of previous TB treatment, DM status, HIV status, resistance pattern, initial sputum examination results, drug side effects, treatment initiation interval, body mass index, and BPJS ownership status. Statistical analysis was done using SPSS version 22 software, with logistic regression analysis to identify the determinants. The determinant of unsuccessful treatment outcome in Central Java Province which is 51.04% was the positive results of initial sputum examination of treatment (aOR=10.501; 95%CI=5.056-21.807), drug side effects (aOR=1.853; 95%CI=1,000-3.436), obesity (aOR=3.115; 95%CI=1.188-8.166) and BPJS non-possession status (aOR=2.213; 95%CI=0.932-5.255). More strategies are needed to improve the success of treatment with STR.
Co-Authors Ardiani, Intan Henda Azizah Dwi Sarwani Sri Rejeki Saefurrohim, Muhamad Zakki