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PEMBERIAN EDUKASI TENTANG CARA MENGATUR OBAT BAGI LANSIA AGAR TETAP SEHAT SELAMA RAMADHAN DI UPT PSTW HUSNUL KHOTIMAH Djohari, Meiriza; Pratiwi, Erniza; Fadhli, Haiyul; Safitri, Devi; Rifani, Mhd; Putri, Sella Hilmalia Nur Al; Sumbarita, Silvia; Rahmatunnur, Siti; Mardianti, Tengku Shella; Muti’ah, Try Hadirah; Azizah, Wahyu; Zamri, Wiedya Alfitrya; Maqfiroh, Wirdarani
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 7 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Juli 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i7.1574

Abstract

Elderly people who undergo regular drug therapy often face problems in adjusting the time they take medication during fasting. This is due to changes in eating schedules during Ramadan. Some medications may require adjustments in dose, frequency, or even formulation so that they continue to work well. The aim of this service is to increase public understanding, especially the elderly, about how to manage medication schedules and doses during fasting. Service activities are carried out using a demonstration and discussion system by giving brochures to the elderly at UPT PSTW Husnul Khotimah. Starting from filling out the questionnaire sheet (pre-test), distribution of brochures, verbal education and ending with filling out a questionnaire sheet (post-test) related to participants' understanding of the information that has been presented. Based on the results, an increase in the average value was obtained pre-test by 41.25% to 72.16% in post-test, and in statistical tests with Paired Sample Test shows a significance value of 0.000, which indicates there is a significant difference between before and after counseling. So it can be concluded that the counseling carried out at UPT PSTW Husnul Khotimah significantly increased the knowledge of the elderly, especially regarding the use of medication during fasting.
Potensi Aktivitas Antimalaria Residu Hidrodestilasi Kulit Kayu Manis (Cinnamomum Burmanii) Melalui Penghambatan Polimerisasi Heme Dona, Rahma; Almurdani , M; Rivan , M; Ibad, M Zainul; Syafitri, Ikke Juwita; Azizah, Wahyu; Nur, Siti Rahmatun; Lestari, Putri
Jurnal Riset Kimia Vol. 15 No. 2 (2024): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i2.711

Abstract

Cinnamon (Cinnamomum burmanii) is a herbal plant from Indonesia which is widely used in cooking, cosmetics and medicine. Cinnamon bark isolate is thought to contain compounds with the structure of isoquinoline which are known to be used as antimalarials. The aim of this study was to examine the potential antimalarial activity of extracts and fractions of cinnamon bark hydrodistillation residue based on the % inhibition and IC50 value. These results will also be compared with extracts and fractions of cinnamon bark without hydrodistillation as controls. The test method is carried out in vitro by heme polymerization inhibitor. The test results showed that the n-hexane fraction, DCM fraction did not have inhibitory activity, while the ethyl acetate fraction had better potential than other extracts and fractions, where the ethyl acetate fraction after hydrodistillation (residue) had an IC50 value of 71.84 µg/mL, while the ethyl acetate fraction without hydrodistillation (control) had an IC50 value of 120.05 µg/mL. This result is better than hydroxychloroquine as positive control which has an IC50 value of 184.98 µg/mL. These results indicate that the ethyl acetate fraction from the hydrodistillation residue of cinnamon bark can be utilized and has potential as an antimalarial.