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All Journal BIOLINK (Jurnal Biologi Lingkungan, Industri, Kesehatan) JFM (Jurnal Farmasi Malahayati)
Adhila, Ghina
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Medicine & Pharmacology

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ECO-FRIENDLY INNOVATION: POTENTIAL OF RED DRAGON FRUIT PEEL EXTRACT IN SILVER NANOPARTICLE BIOSYNTHESIS Dwi Puspita, Alfiana; Adhila, Ghina; Sari, Della Puspita; Wicaksono, Sigit Candra; Fahriati , Zahira
BIOLINK (Jurnal Biologi Lingkungan Industri Kesehatan) Vol. 12 No. 1 (2025): Biolink August
Publisher : Universitas Medan Area

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31289/biolink.v12i1.13331

Abstract

East Kalimantan is one of the regions that cultivates red dragon fruit (Hylocereus polyrhizus) in large quantities due to its promising health benefits. The peel of red dragon fruit has antioxidant activity comparable to its flesh, yet it is rarely utilized and often discarded as organic waste. This study aims to explore the potential of water and ethanol extracts from red dragon fruit peel as antioxidant sources that can serve as natural reducing and stabilizing agents in the biosynthesis of silver nanoparticles (AgNPs). Extraction using water and ethanol solvents was conducted to analyze the antioxidant compounds in the peel. The extract with the strongest antioxidant activity was used for AgNP biosynthesis, and the absorption peak was observed using UV-Vis spectrophotometry at a specific wavelength of 400–450 nm, which is characteristic of AgNP surface plasmon resonance. The results showed that the ethanol extract exhibited stronger antioxidant potential based on its lower IC₅₀ value and functioned effectively as a reducing and stabilizing agent at synthesis temperatures of 40–50°C, without degrading the extract's secondary metabolites. These findings support the utilization of red dragon fruit peel as a sustainable and eco-friendly raw material for the development of health-related products.
UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA EKSTRAK METANOL KULIT BUAH MARKISA UNGU (Passiflora edulis f. edulis Sims) DENGAN SPEKTROFOTOMETRI UV-VIS Sundu, Reksi; Jubaidah, Siti; Milasari, Novi; Adhila, Ghina
JFM (Jurnal Farmasi Malahayati) Vol 8, No 2 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i2.21642

Abstract

Tabir surya dapat membantu mencegah efek buruk radiasi ultraviolet. Efektivitas tabir surya didasarkan pada penentuan nilai Sun Protection Factor (SPF) yang menunjukkan kemampuan produk tabir surya dalam melindungi kulit dari paparan sinar UV. Nilai SPF besar atau kecil dipengaruhi oleh kandungan antioksidan dan bahan aktif yang digunkan dalam membuat sediaan tabir surya. Antioksidan alamiah tubuh berfungsi sebagai sistem pertahanan untuk melindungi sel-selnya dari kerusakan yang disebabkan oleh radikal bebas. Ekstrak kulit buah markisa ungu mengandung senyawa karotenoid, polifenol, dan vitamin. Tujuan dari penelitian ini untuk mengetahui aktivitas antioksidan dan tabir surya ekstrak methanol kulit buah markisa ungu (Passiflora edulis f. edulis Sims). Metode penelitian menggunakan metode DPPH secara Spektrofotometri UV-Vis. Metode Penelitianmenggunakan metode DPPHsecara Spektrofotometri UV-Visc Hasil penelitian menunjukkan metabolit sekunder yang terdapat dalam ekstrak metanol kulit markisa ungu flavonoid, tanin, saponin, alkaloid, dan terpenoid. Aktivitas antioksidan ekstrak metanol kulit markisa ungu didapatkan nilai IC50 sebesar 125,13 ±13,22 termasuk dalam kategori sedang dan pembanding vitamin C sebesar 7,17 ± 0,60 termasuk dalam ketegori sangat kuat. Nilai tertinggi SPF terdapat pada konsentrasi 2.000 ppm yaitu 30,03 ± 0,24 dan termasuk dalam kategori tinggi
Co-Authors Fahriati , Zahira Milasari, Novi Puspita, Alfiana Dwi Reksi Sundu Sari, Della Puspita Siti Jubaidah, Siti Wicaksono, Sigit Candra