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All Journal JURNAL KESEHATAN YAMASI MAKASSAR
Kasim, Rezky Amaliah
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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UJI AKTIVITAS FRAKSI N-HEKSAN, ETIL ASETAT, ETANOL DAUN PARE (Momordica charantia L.) TERHADAP Staphylococcus epidermidis DAN Salmonella thypi Muhammad Asri SR; Suryanita; Kasim, Rezky Amaliah
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.380

Abstract

Bitter melon leaves (Momordica charantia L.) contain compounds such as flavonoids, saponins, triterpenoids, glycosides and alkaloids. This study aims to determine the difference in antibacterial activity of the N-hexane, Ethyl acetate and Ethanol 96% fractions fram bitter melon leaves (Momordica charantia L.) against the bacteria Staphylococcus epidermidis and Salmonella thypi. The research method is an experimental study to see the antibacterial activity of the N-hexane, ethyl acetate and etanol 96% fractions at concentrations of 5%, 10% and 15% using the disc diffusion method. The results of the research showed that Staphylococcus epidermidis bacteria obtained an inhibitory power of 5% (5,95 mm), 10% (12,23 mm), 15% (14,05 mm) for the N-hexane fraction. Ethyl acetate fraction 5% (6,08 mm), 10% (7,37 mm), 15% (10,93 mm). Ethanol fraction of 5% (6,37 mm), 10% (12,8 mm), 15% (13,98 mm). Salmonella thypi bacteria against the N-hexane fraction obtained an inhibitory power of 5% (7,83 mm), 10% (12,47 mm), 15% (13,88 mm). The ethyl acetate fraction is 5% (5,43 mm), 10% (10,85 mm), 15% (13,88 mm). Ethanol fraction of 5% (7,77 mm), 10% (10,27 mm), 15% (15,5 mm). It can be concluded that the N-hexane, ethyl acetate and ethanol 96% fractions have antibacterial activity.
Co-Authors Muhammad Asri SR Suryanita