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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Ina Kidney
Veronike, Evelin
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health

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Profile of Catheter-Related Infections in Hemodialysis Patients with Double Lumen Catheters at Dr. Reksodiwiryo Hospital, Padang Putra, Mindy Pasuma; Vidiansyah, Achmad; Veronike, Evelin; Harun, Harnavi
Indonesian Journal of Kidney and Hypertension Vol 2 No 2 (2025): Volume 2 No. 2, August 2025
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v2i2.189

Abstract

Background: Hemodialysis (HD) is the primary therapy for patients with advanced-stage chronic kidney disease (CKD). Although effective, the use of double lumen catheters (CDL) as vascular access in HD carries a high risk of infection. Objective: This study aims to identify the infection profile in CKD patients using CDL during hemodialysis at Dr. Reksodiwiryo Hospital in Padang. Methods: This study employs a retrospective descriptive design involving 60 hemodialysis patients from May to July 2024. The variables analyzed include age, gender, etiology, clinical manifestations, catheter location, catheter duration, and hematological parameters (leukocytes), with catheter-related infections (CRI) as the main dependent variable. Results: The results show that the majority of patients were under 60 years old (51.7%), and more than half (56.7%) used CDL for less than 8 weeks. CDL infections most frequently occurred in the right jugular vein access (90.0%) with fever and chills as the primary symptoms (53.3%). Conclusion: Using CDL for less than 8 weeks is linked to a high infection rate, with fever and chills as common symptoms. Recommendations include strict aseptic techniques during catheter insertion, prophylactic antibiotics for high leukocyte levels, and early planning for arteriovenous fistula (AVF) to minimize complications from long-term catheter use.
Correlation Between Oxidative Stress, SIRT1 Serum Level, and eGFR on Elderly Harun, Harnavi; Veronike, Evelin; Kam, Alexander; Amelia, Rinita
Jurnal Penelitian Pendidikan IPA Vol 9 No 8 (2023): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i8.4916

Abstract

The aging network kidney causes Oxidative Stress (OS) and damages the kidney. Studies of aging kidneys keep going growing by developing sirtuin as an antiaging. Sirtuin 1 (SIRT1) is a protein implicated in several disorders including diabetes functions as an anti-aging protein. Decreased eGFR in the elderly caused by his height prevalence factor risk disease kidney at an older age. The study aims to study the correlation between oxidative stress, SIRT1 serum levels, and eGFR in the elderly.  The method used in this research is observational with the cross-sectional method. The sample in this study was the whole elderly who met the inclusion and exclusion criteria, totaling 30 people. Exclusion criteria are patients with glomerulonephritis, nephropathy obstruction, nephropathy sour veins, and obesity. All patients complied requirements asked to fill informed consent form. The inspection was carried out by urinalysis ultrasound kidney and assessing serum MDA levels which were found to be higher in this study. This study showed SIRT1 and eGFR levels decreased in the elderly. There was a negative correlation with moderate correlation strength between serum MDA levels and serum SIRT1 levels and a strong correlation between serum MDA levels and eGFR in the elderly. There was a positive correlation with a moderate correlation between serum SIRT1 levels and eGFR in the elderly. SIRT1 is suggested to be examined in elderly patients with decreased eGFR, even without comorbidity.
Co-Authors Amelia, Rinita Harun Harnavi Kam, Alexander Putra, Mindy Pasuma Vidiansyah, Achmad