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All Journal Quantum Wellness : Jurnal Ilmu Kesehatan
Annisa Nofriani
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Phytochemical Constituents and Pharmacological Potential of Justicia gendarussa Burm. f.: A Review Annisa Nofriani; Naura Nurnahari
Quantum Wellness : Jurnal Ilmu Kesehatan Vol. 2 No. 2 (2025): Juni : Quantum Wellness : Jurnal Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/quwell.v2i2.2283

Abstract

Justicia gendarussa Burm. f., commonly known as gandarusa, is a medicinal shrub widely distributed in South and Southeast Asia. Traditionally, it has been used for treating rheumatism, headache, asthma, bronchitis, skin infections, and as a male contraceptive. Phytochemical analyses revealed the presence of alkaloids (gendarusin A, gendarusin B), flavonoids (quercetin, kaempferol, apigenin), saponins, tannins, phenolics, terpenoids, and Patentiflorin A, a compound with promising anti-HIV activity. Pharmacological investigations demonstrated its anti-inflammatory, analgesic, antimicrobial, antioxidant, antidiabetic, hepatoprotective, immunomodulatory, anticancer, and contraceptive potentials. This review highlights the phytochemical profile, pharmacological properties, and future prospects of J. gendarussa, emphasizing its potential as a phytopharmaceutical candidate. Further studies are required to standardize extracts, confirm clinical efficacy, and ensure long-term safety.
Co-Authors Naura Nurnahari