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Cranberry extract for urinary tract infection treatment in pregnancy: A systematic review Hakim, Rahmawati Abdul; Putri, Dhian Eka; Rahajeng
Majalah Obstetri & Ginekologi Vol. 33 No. 2 (2025): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I22025.121-131

Abstract

HIGHLIGHTS Cranberry represents a promising and effective alternative for both the treatment and prevention of urinary tract infections during pregnancy. Cranberry acts by inhibiting bacterial adhesion to the urinary tract epithelium and exerting direct antibacterial activity.   ABSTRACT Objective: Urinary tract infections (UTIs) represent the second most common infectious disease worldwide, affecting nearly 150 million people annually. Owing to anatomical and physiological alterations, UTIs are especially frequent during pregnancy, manifesting with symptoms including dysuria, cloudy urine, increased urinary frequency, and occasionally hematuria. Recurrent UTIs are defined as two or more episodes within six months or three episodes within a year. Cranberries are widely recognized for their potential in preventing UTIs during pregnancy. Their protective action involves blocking the adhesion of uropathogenic bacteria to the urinary tract epithelium, a process mediated by phenolic compounds and A-type proanthocyanidins (PACs). Materials and Methods: In this systematic review, the authors searched PubMed, ScienceDirect, ResearchGate, and Google Scholar for eligible articles published from 2013 to 2024. The search strategy employed Medical Subject Headings (MeSH) and keywords pertaining to Cranberry Extract/Juice and UTI Assessment Methods in Pregnancy. Search expressions were adapted to the specific requirements of each database to optimize retrieval precision. All identified studies were assessed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: Of the 30 studies included, a daily administration of 500 mg cranberry extract over six months exhibited notable effectiveness as an alternative therapeutic approach for UTIs in pregnancy. Conclusion: Cranberry (Vaccinium macrocarpon) extract prevents UTIs by impeding bacterial adherence and exerting antibacterial properties. This review supports cranberry as a promising and safe alternative for UTI prevention and management in pregnancy, appropriate for routine daily use.
The Relationship Between Family Knowledge and Attitudes Toward the Prevention of Dengue Fever in Children Putri, Dhian Eka; Nurvinanda, Rezka; Lestari, Indri Puji
Genius Journal Vol. 6 No. 2 (2025): GENIUS JOURNAL
Publisher : Inspirasi Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/gj.v6i2.799

Abstract

Introduction: Dengue Hemorrhagic Fever (DHF) remains a major public health concern in tropical countries, including Indonesia, where recurring outbreaks continue to contribute significantly to morbidity and mortality rates. Despite various preventive programs, such as mosquito nest eradication (PSN) and public education, the increasing incidence of DHF—especially among children—indicates that community knowledge and attitudes toward prevention remain insufficient. Objective: This study aims to determine the relationship between family knowledge and attitudes toward the prevention of DHF in children in the working area of Puskesmas Mentok in 2025. Method: This study used a cross-sectional design with a correlational analytic approach. The sampling technique was purposive sampling, involving 100 respondents who were families with children in the working area of Puskesmas Mentok. Data were collected using a questionnaire that had been tested for validity and reliability. Data analysis was conducted through univariate and bivariate analysis using the Chi-Square test with a significance level of 0.05 Result: The results of this study showed a significant relationship between family knowledge and DHF prevention in children (p=0.001). There was also a significant relationship between family attitudes and DHF prevention in children (p=0.001). This indicates that family knowledge and attitudes positively influence preventive actions against DHF. Conclusion: The conclusion of this study is that the higher the level of family knowledge and attitudes, the better the preventive actions for DHF in children. It is recommended that Puskesmas and related institutions continuously enhance health promotion and family health education programs through counseling, healthy environment campaigns, and family education to increase public awareness in DHF prevention.