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All Journal Indonesian Journal of Medical and Pharmaceutical Science Jurnal Ilmiah Nusantara
Susilowati, Dwi Retna
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Chemistry Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health Social Sciences

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EVALUATION OF PROPHYLACTIC ANTIBIOTIC USE IN CESAREAN SECTION PATIENTS AT “X” REGIONAL HOSPITAL, SEMARANG REGENCY lisaIstikhomah; Nisa Febrinasari; Susilowati, Dwi Retna
SAINS INDONESIANA Vol. 3 No. 3 (2025): Vol. 3, No. 3 Edisi Juni 2025
Publisher : Gamma Publishing

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Abstract

Cesarean section is a surgical procedure performed to deliver a baby by making an incision through the mother’s abdominal wall and uterus. As with any surgical intervention, it carries a risk of Surgical Site Infection (SSI). Prevention of SSI can be achieved through the administration of prophylactic antibiotics, which should be given prior to surgery, particularly in clean and clean-contaminated procedures. From an Islamic perspective, as mentioned in Surah Al-Qamar (verse 49), everything should be in accordance with a set measure. Therefore, this study aims to evaluate the appropriateness of prophylactic antibiotic use based on established clinical guidelines. This study employed a descriptive design with data collected retrospectively. The data consisted of medical records of patients who underwent cesarean section at “X” Regional General Hospital in Semarang Regency. The collected data were then compared with the standards outlined in the Indonesian Ministry of Health Regulation No. 28 of 2021. The findings showed that 52.46% of the prophylactic antibiotics used were in accordance with the guidelines, while 47.54% were not. In terms of dosage, 52.46% of Cefazolin 2 grams administrations were appropriate, while 47.54% of Metronidazole 500 mg administrations were deemed inappropriate. However, the timing of antibiotic administration was found to be 100% appropriate across all cases.
Pengaruh Pemberian Obat Asam Folat, Eritropoietin dan Kombinasi Asam Folat Eritropoietin dalam Meningkatkan Hemoglobin pada Pasien Hemodialisa di RSUD dr. Gunawan Mangunkusumo Purnami, Islina Dewi; Indriani, Yonanda Pratiwi; Susilowati, Dwi Retna
Indonesian Journal of Medical and Pharmaceutical Science Vol. 3 No. 1 (2024)
Publisher : Sultan Agung Islamic University of Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijmps.v3i1.136

Abstract

Background: Anemia is a decrease in the total amount of hemoglobin or the number of red blood cells which causes insufficient oxygen supply to meet the body's physiological needs. This study aim to determine the effect of administration of folic acid, erythropoietin (hemapo) and erythropoietin folic acid combinations in increasing hb in hemodialysis patients at RSUD dr. Gunawan Mangunkusumo. Methods: This research is a non-experimental study using a cross-sectional design. Data collection was carried out retrospectively using medical records taken at the medical record unit which received treatment therapy with folic acid, erythropoietin and erythropoietin folate combination in outpatient hemodialysis patients. The sampling technique was carried out by purposive sampling technique. Data obtained during the study were analyzed using the Paired T-test (p-Value = <0.05). Results: Based on the Paired T-Test analysis, it is known that the p-Value = 0.001, this indicates that there is a significant difference in changes in hemoglobin levels before and after consuming folic acid, erythropoietin (hemapo), and the combination of increased Hb in hemodialysis patients at RSUD dr. Gunawan Mangunkusumo. Conclusion: The results of research that has been conducted usingOthe Paired T-Test show that there is a significant difference in changes in hemoglobin levels before and after consuming folic acid, erythropoietin (hemapo), and the combination in increasing Hb in patients at RSUD dr. Gunawan Mangunkusumo.
Co-Authors Indriani, Yonanda Pratiwi lisaIstikhomah Nisa Febrinasari Purnami, Islina Dewi