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All Journal SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL
Musthafa, Ferdian
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Chemical Engineering, Chemistry & Bioengineering Health Professions Medicine & Pharmacology

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Prolotherapy as a Novel Adjunct in Post-Stroke Pain Management: A Pilot Study at RSUD Dr. Saiful Anwar Malang Lestari, Dwi Indriani; Rahmad; Pringga, Gutama Arya; Pambayun, Sheilla Elfira San; Musthafa, Ferdian; Puspitasari, Yuan Laura; Ichsan; Noor, Syeda Tazkia; Zulfikar, Dilloniar Bahny; Ariani, Maydah
Surabaya Physical Medicine and Rehabilitation Journal Vol. 7 No. 2 (2025): SPMRJ, AUGUST 2025
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v7i2.65514

Abstract

Background: Post-stroke pain (PSP) and musculoskeletal complications significantly hinder recovery and quality of life in stroke survivors. Prolotherapy, a regenerative injection therapy, has shown promise in managing musculoskeletal disorders but remains underexplored for PSP. Aim(s): This study evaluates the effectiveness of prolotherapy in reducing pain, improving range of motion (ROM), and enhancing functional outcomes in PSP patients. Material and methods: This pilot study employed a pre-experimental design with pretest and posttest measurements. Conducted at RSUD Dr. Saiful Anwar Malang, the study included three stroke patients experiencing chronic musculoskeletal pain. Prolotherapy injections containing hypertonic dextrose were administered at regular intervals. Primary outcomes included pain (Numerical Rating Scale), ROM, and spasticity (Modified Ashworth Scale). Secondary outcomes were assessed using the Barthel Index, Short Form-36, and Fugl-Meyer Assessment. Statistical analyses were descriptive, with paired t-tests applied to outcome changes. Result: Significant improvements in pain levels (mean NRS reduction from 5.67±1.5 to 3.0±2.0) and ROM, particularly in shoulder flexion and wrist extension, were observed. Spasticity showed minor improvements in some muscle groups. Functional outcomes, including Barthel Index and SF-36 scores, demonstrated positive trends, with two participants improving from severe dependency to moderate independence. Conclusions: Prolotherapy shows promise as an adjunctive intervention for PSP, offering potential benefits in pain reduction and functional recovery. As the first study of its kind at RSUD Dr. Saiful Anwar Malang, it lays the groundwork for future large-scale research to validate these findings and refine clinical applications. Keywords: Stroke, Prolotherapy, Pain, Rehabilitation, post-stroke pain, functional performance
The The Effects of Vitamin D Supplementation on Geriatric Patients with Chronic Low Back Pain Nugroho, Mohammad Barlian; Anggraini, Vivid Prety; Hapsari, Rosalyna Pudji; Musthafa, Ferdian; Kurniani, Nadia; Ulfah, Nisa
Surabaya Physical Medicine and Rehabilitation Journal Vol. 8 No. 1 (2026): SPMRJ, FEBRUARY 2026
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v8i1.67400

Abstract

Background: Low back pain (LBP) is pain or discomfort occurring in the area below the costal margin and above the gluteal fold. Previous studies showed that vitamin D supplementation can alleviate complaints of chronic LBP. Aim: This study investigated the effect of vitamin D supplementation on pain and quality of life in elderly patients with chronic LBP. Material and methods: This study uses the experimental method of randomized controlled trial pre- and posttest design on 16 geriatric patients who were divided into two research groups (intervention and control group). The intervention group had usual rehabilitation therapy and vitamin D3 supplementation at a dose of 5000 IU, whereas the control group only had usual rehabilitation therapy. Pain was measured by the Numerical Rating Scale (NRS), level of vitamin D, and quality of life was assessed by the Short Form (SF-36) before and after 4 weeks.   Result: Both groups, rehabilitation only and rehabilitation combined with vitamin D3, had significant pain reduction after 4 weeks of treatment (p < 0.002 and 0.006 consecutively), but no significant difference between groups (p = 0.893). Conversely, there was statistically significant improvement in the level of vitamin D ( p = 0.026 (p < 0.05)) and SF-36 component vitality ( p = 0.014 (p < 0.05)), mental health ( p =  0.014 (p < 0.05)), social function ( p = 0.006 (p < 0.05)), and pain in the body ( p = 0.002 (p < 0.05)). Conclusions: The administration of vitamin D supplements in patients with chronic LBP has the potential to alleviate symptoms and provide significant benefits in enhancing the patient's quality of life.
Co-Authors Anggraini, Vivid Prety Ariani, Maydah Hapsari, Rosalyna Pudji Ichsan Kurniani, Nadia Lestari, Dwi Indriani Noor, Syeda Tazkia Nugroho, Mohammad Barlian Pambayun, Sheilla Elfira San Pringga, Gutama Arya Puspitasari, Yuan Laura Rahmad Ulfah, Nisa Zulfikar, Dilloniar Bahny