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Herbal Leaf Tea as an Economic and Health Potential of the Suci Village Community, Panti – Jember Dwinianti, Edia; Setyati, Dwi; Rosida, Waki'atil; Mustafidah, Qori'atul; Su'udi, Mukhamad
Jurnal Inovasi Sains dan Teknologi untuk Masyarakat Vol. 3 No. 1 (2025): Mei
Publisher : Faculty of Mathematics and Natural Sciences, University of Jember. Jl. Kalimantan No.37, Krajan Timur, Jemberlor, Kec. Sumbersari, Jember Regency, East Java 68121

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/instem.v3i1.5355

Abstract

The community in Suci Village, Panti Jember has recognized and cultivated family medicinal plants (TOGA) to provide traditional medicine because of its distance from the city center, limited health facilities and pharmacies. The utilization of TOGA is still limited as herbal medicine through liquid herbal medicine which is less practical and has a short shelf life, so it is necessary to carry out mentoring activities in the development of TOGA for herbal tea leaves. This activity aims to empower the community in Suci Village in optimizing the potential and utilization of local biodiversity as an ingredient for leaf herbal tea. The method of activity implementation included lectures, hands-on practice of making herbal tea leaves and discussions. The Biology lecturer team at the University of Jember introduced the local potential, health benefits of herbal tea leaves, and the production process from washing, drying, packaging, to marketing. The results of this activity showed that the socialization of the potential, benefits and production of herbal tea leaves increased community knowledge by 84% in the utilization of local plants for health and economic potential. In addition, interactive discussions generated additional ideas such as the utilization of beluntas leaves and coffee peels as herbal tea ingredients, as both ingredients are available in Suci Village and have not been optimally utilized. Through this activity, it is hoped that the community in Suci village will be able to develop herbal tea through the utilization of local potential that has health benefits and economic potential through environmentally friendly products.
In Silico Biological Activity Prediction of Bioactive Compounds from Dumortiera hirsuta (Sw.) Nees. Using Way2Drug PASS Online Farhan, Abdillah Maulana; Rosida, Waki'atil; Ulum, Fuad Bahrul
Life Science and Biotechnology Vol. 3 No. 1 (2025): May 2025
Publisher : Department of Biology, Faculty Mahematics and Natural Sciences, University of Jember

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Abstract

The liverwort Dumortiera hirsuta (Sw.) Nees. is recognized as a potential source of pharmacologically active metabolites. Bioactive compounds from D. hirsuta have been previously reported through in vitro metabolomic analyses using gas chromatography–mass spectrometry (GC–MS) and liquid chromatography–mass spectrometry (LC–MS). In this study, the biological activities of the GC-MS-identified metabolites were evaluated in silico using the Way2Drug PASS Online platform. The results indicated that ten metabolites from D. hirsuta exhibit medicinal potential, with Pa values greater than 0.7, suggesting a high probability of biological activity. Among these compounds, stigmasterol (Pa = 0.970) and lathosterol (Pa = 0.960) demonstrated the strongest antihypercholesterolemic potential, indicating their role as natural agents for reducing cholesterol levels. These findings highlight the pharmacological potential of D. hirsuta metabolites and warrant further validation through in vitro cholesterol-lowering assays to confirm their predicted activities.