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Isolation of Secondary Metabolites of Zingiberaceae Rhizomes by Spectrofotometry and Chromatography: A Review Supartiningsih, Supartiningsih; Mairani, Fridelly; Putri, Ananda Dwi; Panggabean, Indah Elsayanti; Situmorang, Imelda Stefani Overia; Erni, Erni; Marbun, Eva Diansari
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 3 No. 02 (2025): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/nsmrj.v3i02.133

Abstract

The Zingiberaceae family, known as the ginger family, is rich in secondary metabolites that contribute to its extensive use in traditional and modern medicine. Understanding effective methods for isolating these metabolites is crucial for advancing their pharmaceutical and nutraceutical applications. A literature review of 10 journal articles published between 2015 and 2025 was conducted. The focus was on spectrophotometric (UV-Vis, FTIR) and chromatographic (TLC, HPLC, LC-MS) techniques applied to the rhizomes of Zingiberaceae species. Data on compound identification, quantification, and method performance were analysed. Rhizomes of Curcuma aeruginosa, Alpinia purpurata, Zingiber officinale, and Boesenbergia pandurata were reported to contain flavonoids, alkaloids, phenolics, terpenoids, and curcuminoids. Spectrophotometric methods provided functional group identification and estimation of total metabolite concentrations. Chromatographic approaches enabled separation, purification, and structural elucidation with high specificity. Notably, flavenochromane C from Zingiber cassumunar and piperine from Alpinia purpurata were identified using LC-MS and NMR spectroscopy. In addition, TLC-densitometry for curcuminoids and xanthorrhizol in Curcuma xanthorrhiza demonstrated high accuracy and precision. Spectrophotometric techniques offer rapid and cost-effective screening, while chromatographic methods provide detailed identification and quantification of specific compounds. The complementary use of both approaches enhances the accuracy and reliability of isolating Zingiberaceae metabolites, supporting their further utilisation in medicinal research and product development.
Pemanfaatan Media Interaktif untuk Membantu Pendekatan Student-Centered Learning dalam Pembelajaran IPA Putri, Ananda Dwi; Fitriyani, Hanifah; Umayyah, Siti; Azizah, Anisah Nur
Jurnal Pendidikan Tambusai Vol. 9 No. 1 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pembelajaran abad ke-21 menuntut siswa berpikir secara kritis, memiliki ide kreatif, dan kolaboratif. Metode Student-Centered Learning (SCL) memusatkan peserta didik sebagai fokus utama pembelajaran, dengan guru sebagai fasilitator. Media interaktif menjadi solusi untuk menyampaikan materi pembelajaran yang kompleks melalui visualisasi dan interaksi menarik. Penelitian ini mengeksplorasi pemanfaatan media interaktif, khususnya Canva, dalam mendukung SCL pada pembelajaran IPA di sekolah dasar. Dengan metode kualitatif-deskriptif, dengan data diperoleh melalui wawancara, pengumpulan dokumen, dan observasi terhadap seorang guru kelas IV di Jakarta. Hasil penelitian menunjukkan bahwa Canva memudahkan penyajian materi yang atraktif, meningkatkan motivasi, pemahaman konsep, dan keterlibatan siswa. Kendala yang dihadapi mencakup keterbatasan infrastruktur, sinyal, serta kurangnya kompetensi guru dalam menggunakan teknologi. Solusi meliputi pengembangan fasilitas, pelatihan guru, dan dukungan pihak terkait. Penggunaan media interaktif terbukti berdampak positif terhadap pembelajaran IPA dengan meningkatkan hasil belajar siswa, mendorong keterampilan abad ke-21, dan menciptakan pembelajaran relevan. Media Canva merupakan alat efektif untuk transformasi pembelajaran IPA menuju pendekatan yang berpusat pada siswa.
Antidiabetic Power of Belalai gajah Plant (Clinacanthus nutans) Albriyanti, Ariesta; Annisa, Nur; Putri, Ananda Dwi; Panjaitan, Ruqiah Ganda Putri
Jurnal Penelitian Pendidikan IPA Vol 9 No SpecialIssue (2023): UNRAM journals and research based on science education, science applic
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9iSpecialIssue.4477

Abstract

This study aims to determine the decrease in rat blood glucose levels, MDA levels, and the histopathological description of pancreas after giving ethanol extract of belalai gajah plant. This study used 25 rats, grouped into 5, namely normal control, negative control (CMC-Na 0.5% dose 2 mL/200 g b.w), positive control (glibenclamide dose 0.09 mg /200 g b.w), belalai gajah plant ethanol extract (dose 30 mg/200 g b.w., and 60 mg/200 g b.w). Prior to treatment, the rats were induced into diabetes with streptozotocin-nicotinamide. The content of belalai gajah plant was tested phytochemically and antidiabetic. Potential of belalai gajah plant was tested by induction for 14 days. The results showed that ethanol extract of belalai gajah plant contained alkaloids, flavonoids, steroids, terpenoids, and phenolics. The decrease in blood glucose and MDA levels in the group given the ethanol extract of belalai gajah plant at dose of 60 mg/200 g b.w. was the same as the dose of glibenclamide 0.09 mg/200 g b.w. The results of histopathological of pancreas showed that the ethanol extract of belalai gajah plant at dose of 60 mg/200 g b.w. could improve the structure of Langerhans islets in the pancreas of diabetic rats.