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All Journal Kolaborasi Jurnal Pengabdian Masyarakat Jurnal Kesehatan Bakti Tunas Husada
Ramadhan, Fauzan Sebastian
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Chemistry Education Health Professions Medicine & Pharmacology Nursing Public Health

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Menggali Potensi Desa: Pemanfaatan Pangan Lokal dan Edukasi Sanitasi Sehat untuk Generasi Bebas Stunting di Desa Sinagar Wayunah, Wayunah; Zustika, Diana Sri; Ramadhan, Fauzan Sebastian; Sukma, Mentari Nurul; Nurhasanah, Lutfiah; Rahmatunnisa, Rahmatunnisa
Kolaborasi: Jurnal Pengabdian Masyarakat Vol 5 No 5 (2025): Kolaborasi: Jurnal Pengabdian Masyarakat
Publisher : Yayasan Inspirasi El Burhani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56359/kolaborasi.v5i5.627

Abstract

Introduction: Stunting is a major public health problem caused by chronic malnutrition and recurrent infections, resulting in impaired physical growth and cognitive development in children. Sinagar Village has a relatively high prevalence of stunting. Objective: This study aimed to evaluate the effectiveness of the program “Local Food Utilization and Healthy Sanitation Education for Stunting Prevention” in improving community knowledge regarding balanced nutrition, the use of local food, and healthy sanitation practices. Method: The education program was conducted on July 29, 2025, at the Sinagar Village Hall using an educative-participatory and community-based approach. Forty-five participants (pregnant women, breastfeeding mothers, mothers of toddlers, and community health cadres) took part in pre- and post-tests. Data were analyzed using Microsoft Excel to compare mean scores before and after the intervention. Result: The average score from 84.44 in the pre-test to 85.28 in the post-test. Participants demonstrated improved understanding of stunting, the importance of balanced nutrition, exclusive breastfeeding, immunization, and healthy sanitation practices. The program also included the distribution of nutritious milk and fruits, providing additional nutritional intake for target groups. Conclusion: The local food and healthy sanitation education program was effective in enhancing community knowledge for stunting prevention. Continued educational interventions are recommended to promote sustainable behavioral changes that support optimal child growth and health in rural communities.
ANALISIS VARIAN GENETIK DAN EKSPRESI GEN SPESIFIK JARINGAN PADA HIPERTIROIDISME: STUDI BIOINFORMATIKA INTEGRATIF Rahmawati, Rahmawati; Ramadhan, Fauzan Sebastian; Hamidah, Mida; Salasanti, Citra Dewi
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 25 No 2 (2025)
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v25i2.1940

Abstract

Hipertiroidisme merupakan gangguan endokrin yang dipengaruhi oleh faktor genetik, imunologis, dan regulasi ekspresi gen. Penelitian ini bertujuan untuk menganalisis variasi genetik serta pola ekspresi gen spesifik jaringan pada hipertiroidisme menggunakan pendekatan bioinformatika integratif. Penelitian dilakukan secara in-silico menggunakan basis data GWAS Catalog, GTEx Portal, Ensembl Genome Browser, SNPnexus, dan HaploReg v4.2. Identifikasi SNP dilakukan menggunakan kata kunci “Hyperthyroidism” dengan nilai signifikansi genom luas (p < 1×10⁻⁸) dan difokuskan pada varian missense. Analisis dilanjutkan dengan evaluasi ekspresi gen, anotasi genom, prediksi dampak fungsional protein, serta distribusi alel populasi. Hasil penelitian menunjukkan terdapat 506 SNP terkait hipertiroidisme dan 17 missense variant yang berpotensi memengaruhi fungsi protein. Gen yang paling banyak berkaitan dengan regulasi imun dan autoimun tiroid meliputi PTPN22, HLA-DPB1, TAP2, FCRL3, ADCY7, dan TG. Analisis fungsional menunjukkan SNP rs78534766 pada gen ADCY7 termasuk kategori probably damaging. Selain itu, ditemukan perbedaan distribusi alel antar populasi yang menunjukkan adanya variasi kerentanan genetik terhadap hipertiroidisme. Pendekatan bioinformatika integratif mampu memberikan gambaran molekuler yang lebih komprehensif dan berpotensi mendukung pengembangan precision medicine berbasis genomik pada hipertiroidisme.
Co-Authors Citra Dewi Salasanti Diana Sri Zustika, Diana Sri HAMIDAH, MIDA Nurhasanah, Lutfiah Rahmatunnisa, Rahmatunnisa Rahmawati, Rahmawati Sukma, Mentari Nurul Wayunah Wayunah