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All Journal Jurnal Biosense Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Azeli, Saskia Putri
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaruh Teratogen AlCl3 (Aluminium chloride) terhadap Perkembangan Embrio Ayam (Gallus gallus domesticus) Najib Rahman. G; Azeli, Saskia Putri; Hayu, Elvira; Ahda, Yuni; Atifah, Yusni
JURNAL BIOSENSE Vol 6 No 02 (2023): Edisi Desember 2023
Publisher : Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas PGRI Banyuwangi, Jalan Ikan Tongkol No 01, Telp (0333) 421593, 428592 Banyuwangi 68416

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/biosense.v6i02.3364

Abstract

Teratogen berefek membahayakan terhadap perkembangan embrio. Tujuan penelitian ini untuk mengetahui pengaruh teratogen AlCl3 terhadap perkembangan embrio ayam (Gallus gallus domesticus). Metode penelitian ini dilakukan secara eksperimental dengan perlakuan induksi AlCl3 0,2 mg/L dan kontrol (tanpa perlakuan). Pemberian perlakuan diberikan kepada masing-masing 5 butir telur ayam yang kemudian diinkubasi selama 48 jam. Pengamatan preparat embrio ayam menggunakan whole mount method dengan pewarnaan metilen blue dan eosin. Hasil penelitian menunjukkan ukuran embrio pada kelompok perlakuan lebih kecil (0,6 cm) dibandingkan dengan embrio kontrol (1cm). Jumlah somit pada kelompok perlakuan sejumlah 12 pasang sedangkan pada kelompok kontrol 28 pasang somit. Ukuran kepala lebih kecil jika dibandingkan dengan kelompok kontrol. Penelitian ini menunjukkan bahwa AlCl3 dapat menyebabkan malformasi pada embrio ayam, terkait dengan ukuran embrio, jumlah somit, dan ukuran kepala.
Environmental Perspective for System Dynamics Modeling of Stunting Mitigation to Achieve the Sustainable Development Goals in West Sumatra, Indonesia Yuniarti, Elsa; Azzahra, Nabila; Yulhendri, Yulhendri; Heldi, Heldi; Delvina, Mery; Azeli, Saskia Putri
Kesmas Vol. 21, No. 3
Publisher : UI Scholars Hub

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Abstract

This study developed a system dynamics model to simulate stunting reduction in West Sumatra Province, Indonesia, by integrating infant and toddler health, maternal health, and environmental determinants. Secondary data from 2020–2024 on low birth weight, immunization, malnutrition, exclusive breastfeeding, maternal chronic energy deficiency, iron and folic acid supplement distribution, sanitation, and safe drinking water access were compiled from West Sumatra Provincial Health Office and Statistics Indonesia, and validated through consultation with five stakeholder institutions. Causal Loop Diagrams mapped feedback relationships among determinants and were translated into Stock Flow Diagrams using Powersim Studio 10. The model was validated through structural verification, extreme-condition testing, and historical-fit testing. Baseline and intervention scenarios were simulated over 25- to 100-year horizons. Enhanced immunization and breastfeeding increased immunized toddlers from 180,000 to over 240,000 (33% improvement) and reduced malnutrition cases by approximately 25% relative to baseline. In the integrated multisectoral scenario combining maternal nutrition, breastfeeding, immunization, and sanitation improvements, projected stunted toddlers decreased from 164,321 under baseline conditions to 72,143 over 25 years, a 56% reduction, despite the toddler population nearly doubling to 150,473. These findings indicate that coordinated, multisectoral interventions addressing environmental, maternal, and child health determinants can substantially reduce stunting despite population growth and support integrated policies to accelerate SDG 2 achievement in West Sumatra Province and comparable regions.
Co-Authors Atifah, Yusni Azzahra, Nabila Delvina, Mery Elsa Yuniarti Hayu, Elvira Heldi Heldi, Heldi Najib Rahman. G Yulhendri Yulhendri Yuni Ahda