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SYSTEMATIC REVIEW: EVALUATION OF DIAGNOSTIC ACCURACY AND PRACTICAL USEFULNESS OF RAPID DIAGNOSTIC TESTS FOR MALARIA Hayati, Taureni; Rahman, Fawwaz Fathur; Harlinda, Rhevita Apsari; Yukahadi, Abdi Lathif; Maghfiroh, Dina; Ichwan, Faqusierra Puti; Azzahra, Ghitanisa; Amabel, I Made Glorya; H, Mochammad Risyad Ghifari; Pahlevi, Muhammad Dzaki; Urrahmah, Nafisa; Rini, Oktavia Dwi Sapto
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 17 No 2 (2025): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v17i2.3019

Abstract

Malaria remains a significant global health concern, with 249 million cases and 608,000 deaths reported in 2022. Early detection, especially in endemic and resource-limited settings, is crucial to interrupt transmission. Rapid Diagnostic Tests (RDTs) are widely used due to their speed and practicality, requiring no laboratory infrastructure. This review aimed to evaluate the diagnostic accuracy (sensitivity and specificity) of conventional RDTs (HRP2, pLDH, combination) and ultra-sensitive RDTs (uRDTs), and compare their effectiveness across different populations and clinical settings. Literature searches were conducted in PubMed, ScienceDirect, and Cochrane (2020–2025), including studies in English or Indonesian. A total of 30 studies were included based on the PRISMA guidelines, with study populations encompassing children, neonates, adults, pregnant women, clinical patients, and community members in both endemic and imported settings (involving more than 50,000 individuals in total). Most RDTs demonstrated high specificity (>90%), but sensitivity varied widely (0 to >95%), influenced by parasitemia level and population characteristics. HRP2-based RDTs were effective for Plasmodium falciparum, but HRP2 gene deletions caused false negatives. pLDH-based RDTs performed better in multi-species infections. U-RDTs improved the detection of low-density parasitemia, especially in pregnant women and asymptomatic individuals. However, sensitivity declined in neonates and adults with low parasitemia. While some RDTs outperformed microscopy in clinical sensitivity, PCR remains the gold standard, especially for detecting subclinical infections. In conclusion, RDTs provide rapid and specific detection, particularly for moderate to high-density P. falciparum infections. However, in low-density or asymptomatic cases, their limited sensitivity necessitates confirmatory testing using microscopy or PCR.
Peran Battlefield Acupuncture Sebagai Modalitas Analgesia Cepat Pada Nyeri Traumatik Di Medan Tempur Maghfiroh, Dina; Vani, Emya Grace; Ibrahim, Muhammad Taufik; Pradika, Joseph Bagasjati; Rasuli, Muhammad Luthfi Al; Sinabutar, Reinhard Sadrakh; Deta, Yesania Putri Umbu
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.6938

Abstract

Battlefield Acupuncture (BFA) merupakan teknik auricular acupuncture yang dikembangkan oleh Angkatan Udara Amerika Serikat sebagai metode analgesia cepat menggunakan lima titik khusus pada aurikula dengan acupuncture needles tipe semi-permanen. Modalitas ini dirancang untuk memberikan kontrol nyeri segera pada kondisi nyeri akut, termasuk nyeri traumatik yang sering terjadi pada lingkungan militer dan medan tempur. Dalam situasi operasional dengan sumber daya terbatas, BFA menjadi pilihan non-farmakologis yang praktis karena bersifat portabel, aman, dan dapat diaplikasikan dengan cepat oleh tenaga medis terlatih. Review ini dilakukan untuk menilai efektivitas BFA dalam penanganan nyeri traumatik, termasuk kecepatan onset analgesia, durasi efek, keamanan, serta potensi pengurangan kebutuhan analgesik farmakologis. Pencarian literatur dilakukan melalui beberapa basis data seperti PubMed, MEDLINE, Cochrane Library, Scopus, dan Google Scholar. Sebagian besar studi melaporkan bahwa BFA mampu memberikan penurunan nyeri dalam hitungan menit setelah aplikasi, dengan durasi efek analgesia yang dapat bertahan dari beberapa jam hingga beberapa hari. Efek samping minimal, dan teknik ini terbukti bermanfaat dalam kondisi perang, bencana, maupun situasi pra-rumah sakit. BFA dapat disimpulkan sebagai modalitas analgesia yang efektif, aman, murah, dan mudah dibawa, sehingga berpotensi menjadi komponen penting dalam manajemen nyeri traumatik di medan tempur dan kondisi emergensi dengan akses terbatas terhadap obat-obatan.