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All Journal Jurnal Riset Kesehatan Poltekkes Depkes Bandung Journal of Innovative and Creativity
Amabel, I Made Glorya
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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SYSTEMATIC REVIEW: EVALUATION OF DIAGNOSTIC ACCURACY AND PRACTICAL USEFULNESS OF RAPID DIAGNOSTIC TESTS FOR MALARIA Hayati, Taureni; Rahman, Fawwaz Fathur; Harlinda, Rhevita Apsari; Yukahadi, Abdi Lathif; Maghfiroh, Dina; Ichwan, Faqusierra Puti; Azzahra, Ghitanisa; Amabel, I Made Glorya; H, Mochammad Risyad Ghifari; Pahlevi, Muhammad Dzaki; Urrahmah, Nafisa; Rini, Oktavia Dwi Sapto
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 17 No 2 (2025): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v17i2.3019

Abstract

Malaria remains a significant global health concern, with 249 million cases and 608,000 deaths reported in 2022. Early detection, especially in endemic and resource-limited settings, is crucial to interrupt transmission. Rapid Diagnostic Tests (RDTs) are widely used due to their speed and practicality, requiring no laboratory infrastructure. This review aimed to evaluate the diagnostic accuracy (sensitivity and specificity) of conventional RDTs (HRP2, pLDH, combination) and ultra-sensitive RDTs (uRDTs), and compare their effectiveness across different populations and clinical settings. Literature searches were conducted in PubMed, ScienceDirect, and Cochrane (2020–2025), including studies in English or Indonesian. A total of 30 studies were included based on the PRISMA guidelines, with study populations encompassing children, neonates, adults, pregnant women, clinical patients, and community members in both endemic and imported settings (involving more than 50,000 individuals in total). Most RDTs demonstrated high specificity (>90%), but sensitivity varied widely (0 to >95%), influenced by parasitemia level and population characteristics. HRP2-based RDTs were effective for Plasmodium falciparum, but HRP2 gene deletions caused false negatives. pLDH-based RDTs performed better in multi-species infections. U-RDTs improved the detection of low-density parasitemia, especially in pregnant women and asymptomatic individuals. However, sensitivity declined in neonates and adults with low parasitemia. While some RDTs outperformed microscopy in clinical sensitivity, PCR remains the gold standard, especially for detecting subclinical infections. In conclusion, RDTs provide rapid and specific detection, particularly for moderate to high-density P. falciparum infections. However, in low-density or asymptomatic cases, their limited sensitivity necessitates confirmatory testing using microscopy or PCR.
Kinerja Panjang Telapak Tangan sebagai Secondary identifier dalam Identifikasi Korban Tidak Utuh : Suatu Tinjauan Sistematis Sinaga, Marchsel; Tumanggor, Ingwer Jhontri Artahsasta; Amabel, I Made Glorya
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.6160

Abstract

Identifikasi korban tidak utuh menantang kedokteran forensik saat primary identifier seperti DNA tidak tersedia. Panjang telapak tangan berfungsi sebagai secondary identifier untuk estimasi tinggi badan. Tinjauan sistematis ini bertujuan mengevaluasi kinerja panjang telapak tangan dalam identifikasi sisa jenazah tidak utuh. Mengikuti PRISMA 2020, pendekatan kualitatif deskriptif mensintesis data dari 10 studi empiris populasi dewasa (n>3000) di Asia, Afrika, dan Australia, dipilih dari 114 records melalui PubMed, Google Scholar, dan OpenAlex. Protokol pencarian Boolean mengekstrak koefisien korelasi (r=0,55-0,75), model regresi, dan standard error of estimate (SEE ±4-6 cm). Sintesis naratif tematik menilai konsistensi dan variasi populasi-spesifik. Hasil menunjukkan korelasi linier positif signifikan antara panjang telapak tangan dan tinggi badan, dengan akurasi optimal menggunakan rumus populasi-spesifik dan combined hand length. Kesimpulannya, panjang telapak tangan terbukti reliabel sebagai secondary identifier untuk Disaster Victim Identification multidisipliner, meskipun terbatas desain cross-sectional dan celah regional.
Co-Authors Azzahra, Ghitanisa H, Mochammad Risyad Ghifari Harlinda, Rhevita Apsari Hayati, Taureni Ichwan, Faqusierra Puti Maghfiroh, Dina Pahlevi, Muhammad Dzaki Rahman, Fawwaz Fathur Rini, Oktavia Dwi Sapto Sinaga, Marchsel Tumanggor, Ingwer Jhontri Artahsasta Urrahmah, Nafisa Yukahadi, Abdi Lathif