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All Journal MNJ (Malang Neurology Journal) Asian Journal of Health Research
Amri, Zidan Dzulyadain
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Exploring The Effect of Testosterone Hormonal Therapy on Sexual Problems in Postmenopausal Women: A Comprehensive Systematic Review on Clinical Trials Amri, Zidan Dzulyadain; Putri, Annisa Reanimasi Asmoro; Amanda, Nasyabila Anryandi; Torrences, Theodorica; Shadiq, Raihan; Farida, Leny Silviana
Asian Journal of Health Research Vol. 4 No. 2 (2025): Volume 4 No 2 (August) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i2.234

Abstract

Introduction: Sexual dysfunction is a common concern among postmenopausal women. Testosterone therapy has been proposed as a treatment option, yet evidence remains inconsistent.    Material and Methods: We searched PubMed, ScienceDirect, and EBSCOhost (January 2010–December 2024). Randomized controlled trials (RCTs) assessing testosterone versus placebo or control in postmenopausal women were included. Data extraction and synthesis were performed independently by two reviewers. Risk of bias was assessed using the Cochrane RoB 2 tool. RevMan 5.4 was used for meta-analysis.    Results: Seven articles were considered relevant for assessing the effect of testosterone or androgen therapy on sexual function and desire of postmenopausal women (n = 711). The testosterone group showed significant improvement in sexual activity or desire (OD: 3.18, 95% CI: 2.53 - 3.98, p< 0.00001). This result shows that testosterone therapy has the potential to improve sexual activity and desire in postmenopausal women.    Conclusion: Testosterone therapy may improve sexual function in postmenopausal women, but heterogeneity and limited long-term safety data warrant caution. Further high-quality RCTs are needed. 
SENSITIVITY, PRECISION, AND F1 SCORE OF WEARABLE DEVICES IN ABSENCE SEIZURE MONITORING: A SYSTEMATIC REVIEW Amri, Zidan Dzulyadain; Setyoadji, Yusuf Omar; Sadinah, Fahrin; Ernanda, Shelby Amrus; Damayanti, Ria
MNJ (Malang Neurology Journal) Vol. 12 No. 2 (2026): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2026.012.02.12

Abstract

Background: Absence seizure is one of the most common forms of generalized epilepsy. Wearable devices have been proposed as useful tools to improve clinical care by providing continuous monitoring of patients. This study aimed to evaluate the use of wearable devices for detecting and monitoring absence epilepsy. Methods: This systematic review was performed using PRISMA standards and included cohort studies investigating wearable devices as monitoring tools for absence epilepsy. Literature searches were performed in PubMed, Science Direct, Cochrane, and Google Scholar. Results: Eleven cohort studies published between 2012 and 2025 from France, Turkey, Portugal, Netherlands, Denmark, Belgium, Georgia, USA, and Boston were included, with a total of 1,305 participants. All studies assessed wearable devices for detecting absence seizures and reported diagnostic performance using sensitivity, precision, and F1 score. The pooled descriptive synthesis showed a mean sensitivity of 0.897 (range 0.791–1.000; 11 studies), a mean precision of 0.831 (range 0.540–0.950; 7 studies), and a mean F1 score of 0.858 (range 0.740–0.9639; 7 studies). Only descriptive analysis was possible as most studies did not provide raw diagnostic data or confidence intervals. Conclusion: Wearable devices demonstrate promising performance in detecting absence seizures among patients with absence epilepsy, with high sensitivity, acceptable precision, and overall robust F1 scores across the included studies. However, the lack of standardized data reporting and confidence intervals limits the possibility of meta-analysis. Further large-scale prospective studies are required to validate these findings and support clinical implementation.
Co-Authors Amanda, Nasyabila Anryandi Damayanti, Ria Ernanda, Shelby Amrus Farida, Leny Silviana Putri, Annisa Reanimasi Asmoro Sadinah, Fahrin Setyoadji, Yusuf Omar Shadiq, Raihan Torrences, Theodorica