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All Journal Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas
Sari, Asti Marian
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Agriculture, Biological Sciences & Forestry Humanities Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Veterinary Other

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Pengaruh Pemberian Ekstrak Daun Kelor (Moringa Oleifera) Sebagai Antioksidan Terhadap Kadar Malondialdehyde Pada Tikus Model Hiperglikemia Sari, Asti Marian; Yerizel, Eti -; karmia, Hudila Rifa
Majalah Kedokteran Andalas Vol. 48 No. 1 (2025): MKA January 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i1.p63-70.2025

Abstract

Tujuan: Mengetahui pengaruh pemberiak ekstrak Moringa Oleifera terhadap kadar malondialdehyde pada tikus wistar model hiperglikemia. Metode: Penelitian ini melibatkan 20 ekor tikus strain wistar betina yang berumur 8-12 minggu dengan bobot 200-250 gram yang memenuhi kriteria inklusi maupun ekslusi. Tikus dibagi menjadi kelompok empat, yaitu Kelompok kontrol negatif (K-), Kontrol positif (K+), Perlakuan 1 (P1) dan Perlakuan 2 (P2). Kelompok P1 hanya diberikan makan dan minum standar saja, tanpa perlakuan. Kelompok K+ diinjeksi aloksan secara Intraperotoneal dengan dosis 100 mg/kgBB sehingga tikus menjadi hiperglikemia, P1 diberi injeksi aloksan menjadi hiperglikemia dan diberikan ekstrak moringa oleifera dengan dosis 250 mg/kgBB dan P2 injeksi aloksan menjadi hiperglikemia dan diberikan ekstrak moringa oleifera dengan dosis 500 mg/ kgBB selama 21 hari, Pada hari ke-22 semua kelompok diambil darah untuk dilakukan pemeriksaan kadar malondialdehyde. Hasil: Rerata kadar malondialdehid pada K-, K+, P1 dan P2 berturut-turut, yaitu 1,81±0,06 nmol/mL, 3,81±0,24 nmol/mL, 2,55±0,30 nmol/ mL, 2,09±0,21 nmol/mL, dengan nilai p=0,01. Kesimpulan : Pemberian ekstrak moringa oleifera sebagai antioksidan berpengaruh terhadap penurunan kadar malondialdehid
EDUKASI PEMERIKSAAN IVA PADA WANITA USIA SUBUR DI KELURAHAN BATUANG TABA NAN XX KECAMATAN LUBUK BEGALUNG KOTA PADANG Safaringga, Miranie; Desmawati, Desmawati; Yulika, Marzatia; Tasman, Auwilla Marta; Driza, Novi Aulia; Aisyah, Siti; Sari, Asti Marian; Fijri, Kiran Nandini
BULETIN ILMIAH NAGARI MEMBANGUN Vol. 7 No. 3 (2024)
Publisher : LPPM (Institute for Research and Community Services) Universitas Andalas Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/bina.v7i3.514

Abstract

Cervical cancer is the second leading cause of death due to cancer in women after breast cancer, especially in developing countries. The high morbidity and mortality rates of cervical cancer according to WHO are due to delays in treatment. This happens because of the delay in early detection of cancer and the lack of public knowledge about the symptoms of cervical cancer. Based on the results of a survey conducted at RW 1 Batuang Taba Village, Lubuk Begalung District, there were 71% of women of childbearing age who were sexually active, with 93% of them having never done early detection of cervical cancer either by IVA or Pap Smear methods. For this reason, it is necessary to revive public awareness to carry out early detection of cervical cancer, one of which is health education. Based on an analysis of the pretest and posttest questionnaires given to 12 women, the Wilcoxon test showed that the education provided had a significant effect on increasing women's knowledge (Z = -3.126, p = 0.002). The percentage of knowledge increased significantly from 58.3% to 83.3% after education. Apart from that, from the post-test questionnaire, it was also known that as many as 91.7% of women were interested in early detection of cervical cancer. This activity succeeded in increasing the knowledge and interest of women of childbearing age regarding early detection of cervical cancer so that it is hoped that it can increase the awareness of women of childbearing age to carry out early detection of cervical cancer every 5 years in women of childbearing age.
Co-Authors Desmawati Desmawati Driza, Novi Aulia Eti Yerizel Fijri, Kiran Nandini Karmia, Hudila Rifa Miranie Safaringga Siti Aisyah Tasman, Auwilla Marta Yulika, Marzatia