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All Journal Jurnal Intelek Insan Cendikia Journal Health of Indonesian
Althaf Rajahala B Sinun
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Religion Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Biorhythm Analysis Of The Analgesic Effect Of Paracetamol In Inpatients With COVID-19 At The Hospital Yuneka Saristiana; Fendy Prasetyawan; Adiyansyah Lukman Hakim; Althaf Rajahala B Sinun; Deo Rudita Febrian Waly
Journal Health of Indonesian Vol. 2 No. 01 (2024): Journal Health of Indonesian, january 2024
Publisher : Paspama Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/health.v2i01.109

Abstract

The global COVID-19 pandemic has posed unprecedented challenges to global health, impacting healthcare institutions worldwide. Dr. Soedomo Regional General Hospital in Trenggalek has been actively involved in treating COVID-19 patients, emphasizing the need for improved care standards and effective symptom management. Paracetamol, a commonly used medication, is a key focus in this endeavor. This study investigates the chronopharmacology of paracetamol in COVID-19 patients, emphasizing the importance of timing in therapeutic interventions. The research, conducted at Dr. Soedomo Regional General Hospital, involves 100 COVID-19 patients undergoing paracetamol therapy. The analysis includes demographic data, paracetamol administration at different times, and the resulting body temperature changes. The findings reveal that the body's response to paracetamol varies significantly depending on the time of administration. Notably, at 4:00 PM, a more pronounced decrease in body temperature is observed, suggesting a heightened effectiveness of therapy. This phenomenon is attributed to the body's circadian rhythm, influencing physiological functions over a 24-hour period. This study lays the groundwork for the "right time, right dose" concept in clinical practice. Considering the circadian rhythm is essential in designing personalized and effective treatment protocols, aiming for optimal outcomes. Despite limitations, including a small sample size, this research provides valuable insights into the circadian aspects of drug efficacy, paving the way for more tailored treatment approaches.
TINJAUAN KRIMINOLOGIS TERHADAP AKAR PENYEBAB KEJAHATAN: ANALISIS SEBAB TIMBULNYA Adiyansyah Lukman Hakim; Althaf Rajahala B Sinun; Deo Rudita Febrian Waly; Fendy Prasetyawan
Jurnal Intelek Insan Cendikia Vol. 1 No. 1 (2024): Maret 2024
Publisher : PT. Intelek Cendikiawan Nusantara

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Abstract

Dalam negara hukum (rechts staat), hukum mempunyai kedudukan yang utama, apabila hukum dapat memenuhi tugas yang ditetapkan dalam konstitusi kita, yaitu melindungi seluruh rakyat Indonesia dan seluruh tumpahan darah Indonesia. Tugas pemerintah adalah menciptakan sumber daya sosial yang dapat melindungi seluruh rakyat Indonesia dari berbagai perbuatan yang merugikan. Untuk menjelaskan fenomena kejahatan, terdapat disiplin ilmu baru bernama kriminologi yang sangat berkaitan dengan hukum pidana. Beberapa teori yang dikemukakan para ahli telah digunakan untuk menganalisis penyebab terjadinya kejahatan. Berdasarkan laporan Kejahatan Tahun 2023 dataindonesia.id, Kepolisian Indonesia mencatat terdapat 288.472 kejahatan yang terjadi di Indonesia, meningkat 4,33% dibandingkan tahun sebelumnya. sehingga identifikasi faktor-faktor penyebab kejahatan dapat memberikan bahan bagi pengembangan pencegahan kejahatan
Co-Authors Adiyansyah Lukman Hakim Deo Rudita Febrian Waly Fendy Prasetyawan Yuneka Saristiana