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All Journal Biology, Medicine, & Natural Product Chemistry Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Well Being PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara J-CEKI Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Journal Abdimas Paspama Service Jurnal Bioteknologi & Biosains Indonesia
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Analisa Biaya Terapi Antibiotik Ceftriakson pada Pasien Infeksi Demam Tifoid Rawat Inap Rumah Sakit Tahun 2020 Anggi Restyana; Fendy Prasetyawan; Yuneka Saristiana; Nisa Azzahra Dentika; Nina Nur Jannah
Jurnal Ilmiah Universitas Batanghari Jambi Vol 22, No 3 (2022): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v22i3.2286

Abstract

Typhoid fever is an infection of the digestive tract caused by Salmonella typhi (Eberthella typhosa) results in inflammation of the small intestine and the lumen of the digestive tract. Ceftriaxone antibiotic treatment costs for hospitalized typhoid illness patients in 2020 were the focus of this investigation. A cross-sectional strategy was used in the study design, which was based on the collecting of medical records and funding records. From October 2021 to December 2021, the trial was conducted at Hospital X. A sample of typhoid patients admitted to the inpatient ward of Hospital X, with BPJS payment status, was used for this study's data collection. For typhoid patients at Jombang Regency X Hospital, the average cost of ceftriaxone antibiotics totaled IDR 1,502,796 per patient.
UNIFORMITY OF WEIGHT TESTING OF THE RECIPE MIXTURE FOR THE QUALITY OF PARACETAMOL POWDER FOR PEDIATRIC PATIENTS AT KHODIJAH PHARMACY IN JOMBANG REGENCY IN 2022: Uji Keseragaman Bobot Resep Racikan Terhadap Kualitas Serbuk Bagi (Pulveres) Paracetamol Pada Pasien Anak di Apotek Khodijah Kabupaten Jombang Tahun 2022 Yuneka Saristiana; Fendy Prasetyawan; Charliandri Saputra Wahab; Nanda Ardianto; Lily Aina
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 4 No. 2 (2023): Jurnal Inovasi Farmasi Indonesia (JAFI)
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Jenis sediaan farmasi yang sering digunakan untuk anak dan bayi adalah serbuk. Ada dua jenis serbuk oral yaitu terbagi (pulveres) dan tidak terbagi (pulvis). Sediaan pulveres digunakan paling banyak pada pasien anak, mencapai 38% dibandingkan dengan sediaan lain seperti sirup, kapsul, injeksi, dan inhalasi. Ketidakseragaman bobot pada sediaan pulveres dapat terjadi akibat pembagian yang tidak merata, dan ini dapat menyebabkan perubahan dosis. Penelitian digunakan untuk menilai keseragaman bobot resep pulveres mengukur serbuk paracetamol berdasarkan standar farmakope dan persyaratan kualitas yang berlaku. Penelitian ini merupakan ekperimental dengan pendekatan deskriptif dan mengunakan desain Cross sectional dengan menggunakan alat sebagai timbangan analitik milligram. Persyaratan dalam Farmakope Indonesia Edisi III, keseragaman bobot parasetamol dalam resep racikan sediaan serbuk bagi (pulveres) bentuk bungkus (puyer) di apotek Khadijah kabupaten Jombang tidak mencapai standar yang ditetapkan, dengan hanya mencapai 27%.
The Efficacy of Antiviral Medications in Managing Blood Oxygen Levels in Covid-19 Patients Afflicted by Chronic Kidney Conditions Fendy Prasetyawan; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Elsa Mahardika Putri; Yuneka Saristiana; Susilo Margining Raharjo
Contemporary Journal of Applied Sciences Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/cjas.v1i1.7030

Abstract

This research assesses the efficacy and safety of employing antiviral drugs in individuals with COVID-19 and chronic kidney disease. The study results reveal a reduced effectiveness of the drug in enhancing oxygen saturation in patients, as indicated by a p-value of 0.026 for SpO2. Consequently, the administration of antiviral drugs to individuals with chronic kidney disease warrants careful consideration. Moreover, there is a need to pay attention to the safety aspects of antiviral drug utilization, particularly with a p-value of 0.026 for Clcr. It is advisable to refrain from using specific antiviral drugs, such as favipiravir, in COVID-19 patients with chronic kidney conditions. However, contemplating the use of remdesivir at an appropriate dosage may be viable if the patient's glomerular filtration rate (GFR) exceeds 30 ml/minute. The study's conclusion underscores the significance of meticulous and personalized management when employing antiviral drugs in COVID-19 patients with chronic kidney disease. A comprehensive consideration of factors such as effectiveness, safety, and the patient's renal health is imperative to ensure an optimal and tailored treatment approach.
Efficacy of Antiviral Medications in Decreasing Inflammation Levels Among Covid-19 Patients Experiencing Chronic Kidney Disease (CKD) Fendy Prasetyawan; Faisal Akhmal Muslikh; Anis Akhwan Dhafin; Elsa Mahardika Putri; Yuneka Saristiana; Susilo Margining Raharjo
Contemporary Journal of Applied Sciences Vol. 1 No. 1 (2023): November 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/cjas.v1i1.7037

Abstract

Individuals with Chronic Kidney Disease (CKD) face an elevated risk of severe COVID-19 infection. A comprehensive investigation into the effectiveness of antiviral medications in treating COVID-19 patients is imperative. The primary goal is to assess the severity of the illness and the efficacy of antiviral drugs in individuals with COVID-19 and CKD following antiviral treatment at Dr. Soedomo Trenggalek Hospital. This study adopts a cross-sectional approach, employing purposive sampling for sample selection. Retrospective data from 2022 medical records of COVID-19 patients diagnosed with CKD are analyzed. The research findings highlight the efficacy of antiviral drugs in diminishing inflammation levels in COVID-19 patients, as indicated by a significant p-value of 0.000. However, the leukocyte data proved inadequate in determining the reduction in inflammatory levels. Therefore, obtaining data on C-reactive protein (CVR) and lymphocytes is crucial for a more accurate measurement. The p-value for ClCr is 0.842.
IDENTIFIKASI SENYAWA ANTIOKSIDAN EKSTRAK KULIT BUAH MANGGIS (Garcinia mangostana L.) : EKSTRAK KULIT BUAH MANGGIS Saristiana, Yuneka; Wahdi, Achmad; Prasetyawan, Fendy
WELL BEING Vol 9 No 1 (2024): Well Being
Publisher : LPPM STIKes Bahrul Ulum Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51898/wb.v9i1.246

Abstract

This study aims to identify the antioxidant classes in mangosteen rind (Garcinia mangostana L.), which is known to be rich in natural antioxidants. Antioxidants are compounds that can prevent or slow down cell damage caused by free radicals, which can form through metabolism or environmental exposure. The identification and utilization of natural sources of antioxidants are crucial for protecting cells from damage and supporting health. The research process began with the drying and grinding of mangosteen rind into a fine powder, which was then extracted using ethanol to obtain an antioxidant-rich extract. Subsequently, several phytochemical tests were conducted to identify antioxidant classes such as flavonoids, phenolic compounds, and tannins in the extract. The antioxidant activity assay was performed using the DPPH method, an in vitro method to measure antioxidant activity based on the color change of the DPPH solution that reacts with antioxidant compounds. The extract of mangosteen rind contains alkaloid, flavonoid, saponin, tannin, and steroid compounds. Additionally, the extract of mangosteen rind has potential as an antioxidant with an IC50 value of 48.9685 µg/mL.
Morphological Analysis of Ciplukan Plant (Physalis angulata L.) Pollen for Macroscopic Identification Prasetyawan, Fendy; Saristiana, Yuneka; Akhmal Muslikh, Faisal; Hasriyani, Hasriyani; Dian Permatasari, Yunita
International Journal of Science and Environment (IJSE) Vol. 4 No. 1 (2024): February 2024
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijse.v4i1.63

Abstract

This research addresses the prevalence of arthritis in Indonesia, focusing on traditional medicinal plants like Ciplukan due to the side effects of synthetic treatments. Arthritis, affecting 23.6-31.3% of the population, with Osteoarthritis (50-60% in the elderly) being the most common, necessitates alternative, less toxic remedies. Traditional medicine, relying on plant-derived remedies, is explored for its accessibility, affordability, and lower side effects. The study delves into Ciplukan, known for its anti-arthritis properties, conducting in vitro tests on its methanol extract. Results reveal anti-arthritis activity attributed to steroids, flavonoids, and alkaloids. The methodology involves macroscopic and microscopic examinations of Ciplukan plants, verifying authenticity and confirming the accuracy of plant samples. Organoleptic assessments highlight distinctive features, contributing to the plant's identification. Microscopic examination reveals the presence of stomata and palisade cells in the upper epidermis, aligning with literature data. The vascular system analysis emphasizes the efficiency of resource transport and adaptation to environmental changes. In conclusion, the study provides a comprehensive understanding of Ciplukan's characteristics, supporting its potential in arthritis treatment. The findings contribute to the utilization of traditional medicine in healthcare, emphasizing the importance of plant-based remedies with fewer side effects.
EVALUASI PENGGUNAAN OBAT PADA PASIEN HIPERTENSI RAWAT JALAN DI PUSKESMAS “X” KOTA SOLO Octavian Ashido Nababan; Isma Oktadiana; Fendy Prasetyawan; Yuneka Saristiana; Faisal Akhmal Muslikh; Ratna Mildawati
Jurnal Media Akademik (JMA) Vol. 2 No. 2 (2024): JURNAL MEDIA AKADEMIK Edisi Februari
Publisher : PT. Media Akademik Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62281/v2i2.185

Abstract

Hipertensi atau dikenal dengan “Silent Killer” yang merupakan pengukuran tekanan darah yang melebihi normal (140/90mmHg). Obat hipertensi dapat memberikan efek pada saat penggunaannya yang dapat menunjukkan sejauh mana obat yang telah diberikan mencapai terapi yang diharapkan secara praktik klinis. Penelitian ini bertujuan untuk mengetahui bagaimana penggunaan obat antihipertensi, efektivitas penggunaan dan perbandingan efektivitas obat antihipertensi tiap kelompok pada pasien. Penelitian ini merupakan penelitian secara deskriptif retrospektif, artinya didasarkan pada informasi yang diperoleh dari rekam medis pasien dengan melihat kejadian di masa lalu. Pada rekam medis dimasukkan data pasien hipertensi rawat jalan Puskesmas "X" Kota Solo pada bulan September 2023. Berdasarkan temuan penelitian, 40,30% pasien adalah laki-laki dan 59,70% pasien adalah perempuan. Terdapat 46 orang yang berusia lebih dari 60 tahun dan 21 pasien berusia antara 20 dan 60 tahun. Penggunaan antihipertensi sebagai obat tunggal digambarkan sebesar 35,82%, dan sebagai kombinasi, sebesar 64,18%. Studi tersebut mengklasifikasikan kemanjuran obat menjadi dua kategori: obat tunggal dan obat kombinasi. Dua kelompok telah dibandingkan mengenai kemanjuran antihipertensi individu. Hasil penelitian menunjukkan penggunaan obat pada beberapa golongan obat seperti CCB 41,67%. Golongan obat kombinasi CCB+ARB 46,51%. Karena obat antihipertensi mencapai target terapeutik tekanan darah sistolik sekitar 7-13 mmHg dan tekanan darah diastolic sekitar 4-8 mmHg. Perbandingan efektivitas antihipertensi Tunggal golongan ACEI Captopril (5.028/6.677). Golongan ARB Valsartan (16.666/5.715).
Virtual Socialization about the Use of Family Medicinal Plants (TOGA) as an Alternative for Treatment Ratna Mildawati; Bandhi Prasetya Nugroho; Fendy Prasetyawan; Ary Kristijono; Yuneka Saristiana; Isma Oktadiana; Arlan K Imran
Assoeltan: Indonesian Journal of Community Research and Engagement Vol. 1 No. 2 (2023): Indonesian Journal of Community Research and Engagement
Publisher : Edujavare Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70610/assoeltan.v1i2.270

Abstract

The use of plants as a treatment solution, whether as preventive, promotive or curative therapy, is becoming popular again with the public due to the trend of back to nature medicine. Family Medicinal Plants (TOGA) are plants that have medicinal properties and grow around community yards which are managed by families and planted to meet the family's medicinal needs. The development and utilization of family medicinal plant cultivation is very necessary to support public health. This activity is carried out in an effort to provide knowledge to improve health. The target of this health education activity is housewives. The activity method carried out in this community service is outreach using the lecture method and using power point slides which contain explanations of several types of superior family medicinal plants and by inviting the public to plant TOGA. The success of this community service is assessed from the target number of participants of 75%, achievement of goals of 80%, achievement of material targets of 80% and success of planting TOGA at home 80%. The conclusion of this community service is that TOGA education increases people's knowledge and understanding of TOGA
Asistensi Penyusunan Naskah Proposal Penelitian Dan Pengabdian Masyarakat Dengan Metode Lgd (Leaderless Group Discussion) Di Universtias Kadiri Prasetyawan, Fendy; Saristiana, Yuneka; Dhafin, Anis Akhwan; Mildawati, Ratna; Muslikh, Faisal Akhmal; Ariawan, Wahyu
Gotong Royong Vol. 1 No. 1 (2024)
Publisher : CV. Akira Java Bulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63935/gr.v1i1.16

Abstract

The assistance program for drafting research and community service proposals using the Leaderless Group Discussion (LGD) method at Universitas Kadiri aims to enhance the capacity of lecturers and students in producing high-quality and relevant proposals. The LGD method allows each participant to actively engage in discussions without a dominant leader, fostering involvement and constructive collaboration. The program includes preparation, workshop implementation, proposal evaluation, and follow-up stages. Results indicate significant improvements in problem formulation clarity, methodological accuracy, and proposal consistency. Additionally, active participant involvement and the development of collaborative skills were achieved, strengthening an inclusive discussion culture within the academic environment. Evaluations show that the LGD method effectively enhances academic and professional quality, despite challenges in ensuring deep understanding of topics and methodologies. With support from the Universitas Kadiri's Center for Educational Development and Quality Assurance (LP3M) team, this program successfully met its objectives and provides a strong foundation for similar future activities. The outcomes of this program are expected to contribute to improving the quality of innovative and impactful research and community service.
PREVENTION OF GASTROPROTECTIVE ACTIVITY OF CHINESE BETEL EXTRACT (PEPEROMIA PELLUCIDA L.) ON THE HISTOPATHOLOGICAL FEATURES OF THE STOMACH IN A MOUSE MODEL OF GASTROENTERITIS Savitri, Lisa; Prasetyawan, Fendy; Saristiana, Yuneka; Juwita, Syntia Tanu; Amanda, Cornelia; Mebung, Konradus Klala
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.8156

Abstract

Gastroenteritis is a common gastrointestinal disorder characterized by inflammation of the stomach and small intestine, often leading to symptoms such as diarrhea, vomit-ing, and abdominal pain. This study investigates the gastroprotective effects of Pepe-romia pellucida (Chinese betel) extract on histopathological features of the stomach in a mouse model of gastroenteritis. Male Swiss strain mice, aged 2-3 months, were treated with different doses of P. pellucida extract (100, 300, and 500 mg/kg BW) for 7 days after inducing gastroenteritis with Escherichia coli infection. Histopathological ex-amination showed that the extract significantly reduced cell degeneration, necrosis, and polymorphonuclear leukocyte infiltration in the stomach compared to the negative control group. The highest dose (500 mg/kg BW) exhibited the most prominent gastro-protective effect. These results suggest that P. pellucida possesses promising thera-peutic potential for gastroenteritis, possibly due to its bioactive compounds such as flavonoids, tannins, and saponins. Further studies are needed to explore the underly-ing mechanisms and optimize its therapeutic application.
Co-Authors Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Akhmal, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Amanda, Cornelia Ana Amalia Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arsiaty Sumule Ary Kristijono Asrizal Azis Astutik, Widhi Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Charliandri Saputra Wahab Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Emma Jayanti Besan Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fendy Prasetyawan Freitas, Maria Do Carmo Da Costa Hakim, Adiyansyah Lukman Hasriyani Hasriyani Hasriyani, Hasriyani Herman Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Isma Oktadiana Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Kristjono, Ary Laili , Nur Fahma Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan Marhenta, Yogi Bhakti Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Okky Intan Mawarni Oktadiana, Isma Prasetyo Nugroho, Bandhi Prayoga Fery Yuniarto Probosiwi , Neni Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Shinta Mayasari Shinta Mayasari Sugeng, Santoso Sukmawati , Datin An Nisa Susilo Margining Raharjo Tri Wulan, Ema Tsamrotul Ilmi Widhi Astutik Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yunita Dian Permatasari Zahra, Ilhawa