ABSTRACT This study aims to determine the effect of the use of Artificial Intelligence (AI) of the ChatGPT type and learning interest on the learning outcomes of class X students in Office Management and Business Services (MPLB) at SMK Negeri 7 Medan in the 2024/2025 academic year. This study used a quantitative approach with an ex-post facto type. The sample in this study consisted of 69 respondents selected using a purposive sampling technique. Data collection techniques used questionnaires and documentation of daily test scores. Data analysis was performed using multiple linear regression tests, partial tests (t-tests), simultaneous tests (F-tests), and coefficients of determination (R²) using SPSS 26. The analysis results show that the variable Use of Artificial Intelligence of the ChatGPT type (X1) has a positive and significant effect on student learning outcomes with a t-value (calculated) of 19.630 and a Sig. 0.000 <0.05. Similarly, the learning interest variable (X2) also had a positive and significant effect on learning outcomes, with a t-test value of 41.867 and a Sig. 0.000 <0.05. Simultaneously, the F-test value was 1005.627 with a Sig. 0.000 <0.05, indicating that the use of ChatGPT and learning interest together had a significant effect on learning outcomes. The coefficient of determination (R²) of 0.968 indicates that 96.8% of the variation in learning outcomes can be explained by the two independent variables, while the remaining 3.2% is explained by other factors outside this study. Thus, it can be concluded that the use of ChatGPT Artificial Intelligence and learning interest have a positive and significant effect, both partially and simultaneously, on improving student learning outcomes. This study emphasizes the importance of integrating AI-based digital technology and fostering student learning interest to support the achievement of optimal learning outcomes.