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All Journal Heart Science Journal Cardiovascular and Cardiometabolic Journal (CCJ)
Syarifuddin, Fairuz
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Predictors of Radial Artery Occlusion in Patients with Coronary Heart Disease Undergoing Coronary Angiography or Percutaneous Coronary Intervention via Transradial Access Sumadio, Muhammad Yolandi; Sitepu, Inri Pepayosa; Nina Apriyani Harefa; Nova Syafriana; Syarifuddin, Fairuz
Cardiovascular and Cardiometabolic Journal (CCJ) Vol. 6 No. 2 (2025): Cardiovascular and Cardiometabolic Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ccj.v6i2.2025.67-72

Abstract

Background: Transradial approach is currently the most recommended access for coronary angiography and percutaneous coronary intervention (PCI). However, the risk of developing radial artery occlusion (RAO) with this approach is not uncommon. Objective: This study aims to determine the frequency and predictors of RAO in patients undergoing transradial access. Method: This was a prospective study from January 2021 until December 2023. Participants underwent coronary angiography or PCI via transradial access. Radial artery patency was evaluated before and after the procedure. Results: A total of 456 subjects were enrolled for the study. RAO was found in 37 of 456 subjects (8.1%). From the results of the multivariate analysis, it was found that age (p = 0.012), number of catheters used (p = 0.006), and the incidence of hematoma (p < 0.001) were independent predictors of the incidence of RAO. Conclusion: RAO is a common complication of transradial access so identification of high-risk patients, prevention efforts and close follow-up must be carried out to maintain a patent radial artery. Keywords: percutaneous coronary intervention; radial artery occlusion; transradial -- Highlights: 1. Older age, multiple catheter use, and post-procedural hematoma were identified as independent predictors of radial artery occlusion in patients undergoing transradial coronary angiography or PCI. 2. Early recognition of high-risk patients and careful procedural management are essential to prevent radial artery occlusion and preserve long-term radial artery patency
Correlation between iron profile and severity of coronary artery lesion in patients with non-ST segment elevation myocardial infarction Syarifuddin, Fairuz; Andika Sitepu; Abdullah Afif Siregar; Zulfikri Mukhtar; Cut Aryfa Andra; Teuku Bob Haykal; Harris Hasan
Heart Science Journal Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Lo
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.04.12

Abstract

BACKGROUND: Excessive iron has been shown to increase the atherosclerosis process through the help of non-transferrin-bound iron (NTBI). OBJECTIVE: This study aimed to ascertain the association between iron profile and the severity of coronary artery lesions in patients with acute non-ST segment elevation myocardial infarction (NSTEMI).  METHOD: This observational analytical study with a cross-sectional design was conducted from February to September 2024 at Adam Malik General Hospital. NSTEMI patients planned for coronary angiography were examined for iron profile, including serum iron, total iron binding capacity (TIBC), and transferrin saturation. Coronary artery lesion severity was evaluated using the synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score.  RESULTS: This study involved 72 subjects. The results showed there were no correlations between serum iron levels and SYNTAX scores (p = 0.891) and transferrin saturation with SYNTAX scores (p = 0.545). Nevertheless, TIBC and SYNTAX score were negatively correlated (p = 0.004) with a weak correlation coefficient (r = -0.334).  CONCLUSION: TIBC levels are inversely correlated with the severity of coronary artery lesions. However, transferrin saturation and serum iron have not been shown to correlate with the severity of coronary artery lesions.
Co-Authors Abdullah Afif Siregar Cut Aryfa Andra Harris Hasan Nina Apriyani Harefa Nova Syafriana Sitepu, Andika Sitepu, Inri Pepayosa Sumadio, Muhammad Yolandi Teuku Bob Haykal Zulfikri Mukhtar