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All Journal Sumatera Medical Journal SCRIPTA SCORE Scientific Medical Journal Heart Science Journal
Cut Aryfa Andra
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Health Professions Immunology & microbiology Medicine & Pharmacology

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Obstructive Sleep Apnea in Patients with Heart Failure and Atrial Fibrillation Lubis, Anggia Chairuddin; Yuke Sarastri; Cut Aryfa Andra; Nadiah Masyab; Hana Fauziyah
Sumatera Medical Journal Vol. 8 No. 3 (2025): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v8i3.16701

Abstract

Background: Obstructive sleep apnea (OSA) is an independent risk factor for heart failure and atrial fibrillation. Therefore, effective detection and management of OSA are essential. Objective: The study aimed to determine how common obstructive sleep apnea is among patients with heart failure and atrial fibrillation. Methods: We performed a cross-sectional study assessing the prevalence of OSA in hospitalized patients with both conditions, following the latest European Society of Cardiology Guidelines for heart failure assessment and using polysomnography to evaluate OSA. Results: The study included 30 subjects; 22 (73.3%) were men, and 18 (60%) were over 60 years old. Polysomnography revealed that 23 (80.0%) had OSA, with 4 (23.5%) in the severe category and an average AHI of 18.3 ± 14.7. Among participants, 11 (65%) with ejection fraction ≤ 40%, 12 (40%) had obesity, 11 (36.7%) had Type 2 diabetes, 19 (63.6%) had hypertension, 20 (66.7%) had coronary artery disease, and 3 (10%) had a history of stroke. Most participants (60%) had a history of smoking. Conclusion: This study shows a high prevalence of OSA among patients with heart failure and atrial fibrillation, especially in men and those with reduced ejection fraction.
Correlation between iron profile and severity of coronary artery lesion in patients with non-ST segment elevation myocardial infarction Syarifuddin, Fairuz; Andika Sitepu; Abdullah Afif Siregar; Zulfikri Mukhtar; Cut Aryfa Andra; Teuku Bob Haykal; Harris Hasan
Heart Science Journal Vol. 6 No. 4 (2025): The Pursuit of Precision: Navigating Risks, Refining Diagnosis, and Securing Lo
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.04.12

Abstract

BACKGROUND: Excessive iron has been shown to increase the atherosclerosis process through the help of non-transferrin-bound iron (NTBI). OBJECTIVE: This study aimed to ascertain the association between iron profile and the severity of coronary artery lesions in patients with acute non-ST segment elevation myocardial infarction (NSTEMI).  METHOD: This observational analytical study with a cross-sectional design was conducted from February to September 2024 at Adam Malik General Hospital. NSTEMI patients planned for coronary angiography were examined for iron profile, including serum iron, total iron binding capacity (TIBC), and transferrin saturation. Coronary artery lesion severity was evaluated using the synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score.  RESULTS: This study involved 72 subjects. The results showed there were no correlations between serum iron levels and SYNTAX scores (p = 0.891) and transferrin saturation with SYNTAX scores (p = 0.545). Nevertheless, TIBC and SYNTAX score were negatively correlated (p = 0.004) with a weak correlation coefficient (r = -0.334).  CONCLUSION: TIBC levels are inversely correlated with the severity of coronary artery lesions. However, transferrin saturation and serum iron have not been shown to correlate with the severity of coronary artery lesions.
Risk Factors of Acute Coronary Syndrome in Adam Malik General Hospital Jessi Vania Tambarta; Cut Aryfa Andra; Lili Rohmawati; Aryani Atiyatul Amra
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 2 (2025): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i2.19293

Abstract

Background : Coronary Artery Disease (CAD) has been nominated as the world’s biggest killer due to its participation in 16% of mortality cases globally. Unstable Angina Pectoris (UAP), Non ST-Elevation Myocardial Infarction (NSTEMI), and ST-Elevation Myocardial Infarction (STEMI) are parts of CAD that united into a term called Acute Coronary Syndrome (ACS). Several risk factors have been linked to ACS phenomenon and categorized into modifiable and in-modifiable risk factors. Objective : This study aims to discover the existing risk factors in ACS patients at Adam Malik General Hospital within 2022-2023 period. Method :  This study is a descriptive with cross-sectional design and retropective approach. The data is a secondary data from medical record that fullfils the criteria. Result : Among the 190 patients, 170 patients (89,5%) were >45 years old, 114 patients (75,8%) were male, 104 patients (54,7%) were smokers, 118 patients (62,1%) had hypertension, 71 patients (37,4%) had diabetes, 65 patients (34,2%) were obese, and 114 patients (60%) had dyslipidemia. Conclusion : The unmodifiable risk factors in this study were age and gender, whilst the modifiable risk factors were smokers, hypertension, diabetes, obese, and dyslipidemia. The most frequent risk factor was hypertension which was found in 60% of the patients Latar belakang : Penyakit Jantung Koroner (PJK) dimobatkan sebagai penyebab kematian terbesar di dunia akibat perannya pada 16% kasus kematian secara global. Angina Pektoris Tidak Stabil (APTS), Non-ST levation Myocardial Infarction (NSTEMI), dan ST-Elevation Myocardial Infarction (STEMI) adalah bagian dari PJK yang disatukan dalam Sindroma Koroner Akut (SKA). Beberapa faktor risiko telah dihubungkan dengan kejadian SKA dan dikategorikan menjadi faktor risiko yang tidak dapat dimodifikasi dan faktor risiko yang dapat dimodifikasi. Tujuan : Penelitian ini bertujuan untuk menelusuri faktor risiko yang terjadi pada pasien SKA di RSUP Haji Adam Malik pada periode 2022-2023. Data yang digunakan adalah data sekunder dari rekam medik yang memenuhi kriteria. Hasil : Dari 190 pasien, 170 pasien (89,5%) berusia >45 tahun, 114 pasien (75,8%) adalah laki-laki, 104 pasien (54,7%) adalah perokok, 118 pasien (62,1%) penderita hipertensi, 71 pasien (37,4%) penderita diabetes, 65 pasien (34,2%) obesitas, 114 pasien (60%) penderita dislipidemia. Kesimpulan : Faktor risiko yang tidak dapat dimodifikasi pada penelitian ini adalah usia dan jenis kelamin, sementara faktor risiko yang dapat dimodifikasi adalah perokok, hipertensi, diabetes, obesitas, dan dislipidemia. Faktor risiko yang paling banyak terjadi adalah hipertensi yang didapatkan pada 60% pasien
Co-Authors Abdullah Afif Siregar Aryani Atiyatul Amra Hana Fauziyah Harris Hasan Jessi Vania Tambarta Lili Rohmawati Lubis, Anggia Chairuddin Nadiah Masyab Sitepu, Andika Syarifuddin, Fairuz Teuku Bob Haykal Yuke Sarastri Zulfikri Mukhtar