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All Journal ARSHI Veterinary Letters Journal of Applied Veterinary Science and Technology
Andadari, Afifah Yudining Dwi
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Agriculture, Biological Sciences & Forestry Veterinary

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Pain management approach in a cat with feline arterial thromboembolism assessed using the Feline Grimace Scale Napitu , Napitu; Andadari, Afifah Yudining Dwi; Herawati , Herawati
ARSHI Veterinary Letters Vol. 9 No. 3 (2025): ARSHI Veterinary Letters - August 2025
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.9.3.73-74

Abstract

Feline arterial thromboembolism (FATE) is a life-threatening condition characterized by partial or complete arterial obstruction due to thrombus formation, most commonly secondary to hypertrophic cardiomyopathy (HCM). The resulting ischemia causes severe pain, which is often overlooked in clinical practice. The Feline Grimace Scale (FGS) provides a rapid and objective tool for pain assessment in cats. This report describes an adult female cat presenting with left hindlimb paresis, cyanosis, and femoral pulse deficit, with an initial FGS score of 6/10. Blood chemistry showed elevated creatine kinase (CK) levels, and echocardiography confirmed reduced femoral arterial flow and myocardial hypertrophy, consistent with HCM. A multimodal management approach was applied, including gabapentin, tramadol, clopidogrel, furosemide, and heparin therapy. Despite treatment, the affected limb developed gangrene, necessitating amputation. Preoperative analgesia consisted of pethidine, ketamine, and xylazine, followed by regional lidocaine nerve blocks and postoperative fentanyl continuous rate infusion. The surgical site healed completely within 21 days, and over a four-month follow-up period, the FGS score improved from 9 to 0, indicating complete pain resolution.
Literature Study : Histopathology Analysis of Rabies Disease (2014 - 2022) Andadari, Afifah Yudining Dwi; Pratama, Dyah Ayu Oktavianie A.; Hardian, Andreas Bandang; Untari, Handayu
Journal of Applied Veterinary Science And Technology Vol. 5 No. 1 (2024): April 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/javest.V5.I1.2024.93-98

Abstract

Background: Rabies is a contagious and zoonotic disease caused by Lyssavirus, a neurotropic, negative-sense, single-stranded RNA virus. Rabies infects most mammals through the transmission of saliva from a rabid animal that enters the body of a healthy animal through an open wound, bite, scratch, or direct contact. A post-mortem diagnosis and evaluation are crucial for establishing regional statistical data in order to design a robust strategy for combating rabies. Histopathology has long been known to be an invaluable source of information regarding the destructive impact of rabies in nervous tissue. In addition to other ante-mortem evaluations, a correlation between clinical signs, gross pathological findings, and histopathological findings must be established to achieve the maximum target of combating rabies. Purpose: This study aims to analyze and compare gross pathological findings and histopathological findings in the literature published between 2014 and 2022. Methods: A comparison between gross pathological findings and histopathological findings was conducted on case studies from 2014 to 2022. Anamnesis and clinical signs were obtained as supporting data. The findings were presented as percentage to identify the predominant pathological signs. Results: A review of four case studies revealed that paralysis, hyperesthesia, gait abnormality, and muscle tremor were the most commonly observed signs (50%). Only two case studies revealed gross pathological findings, including meningeal congestion and cerebellar hemorrhage. Eight studies identified the intracytoplasmic negri body in Purkinje cells as the most commonly observed histopathological finding (100%). Conclusion: The primary clinical signs and gross pathological findings associated with rabies are typically regarded as non-specific. Histopathology revealed the intracytoplasmic Negri body in Purkinje cells as the most commonly observed finding (100%).
Co-Authors Hardian, Andreas Bandang Herawati , Herawati Napitu , Napitu Pratama, Dyah Ayu Oktavianie A. Untari, Handayu