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All Journal Jurnal Biologi Tropis
Nopiyanti, Tita
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Potential of Mesenchymal Stem Cells (MSCs) for Various Disease Therapy: Systematic Review Aulia, Annisa; Rismayani, Dessy; Nopiyanti, Tita; Noli, Zozy Aneloi; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7006

Abstract

Mesenchymal stem cells (MSCs) are a type of multipotent stem cells that can be found in various tissues of the body, possessing good regenerative qualities and promising immunomodulatory abilities for therapy in various medical conditions. MSCs can be obtained from bone marrow, umbilical cord, adipose tissue, and Warthon's jelly. This study aims to present a systematic review of the use of mesenchymal stem cells in disease therapy, by evaluating the latest evidence regarding their efficacy and safety in various therapies. This review uses literature review methods from international data bases such as PubMed and Google Scholar. The total number of articles obtained from the database was 49 articles. These articles were then filtered using inclusion and exclusion criteria, resulting in 22 articles for this systematic review. The research findings indicate that MSCs therapy has been used for the treatment of liver fibrosis, diabetes mellitus, spinal cord injury, and COVID-19. In MSCs therapy, mechanisms involved paracrine effects (MSCs produce cytokines, growth factors, and other proteins); immunomodulation (MSCs can suppress immune cell activation, inhibit lymphocyte proliferation, modulate natural killer T cell activation, and produce anti-inflammatory factors); angiogenesis (MSCs are capable of stimulating the growth of new blood vessels through secretion of VEGF and FGF); cellular differentiation; and anti-fibrotic effects. This is what makes MSCs potentially promising as an evolving alternative treatment.
Biology of Black Soldier Fly (Hermetia illucens) and Utilization of its Waste (Maggot Frass) for Plant Growth: A Literature Review Idris, Muhammad; Rismayani, Dessy; Aulia, Annisa; Nopiyanti, Tita; Rahayu, Resti
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7226

Abstract

The utilization of maggot frass from Black Soldier Fly (BSF) larvae (Hermetia illucens Linneus, 1875) has garnered attention in the context of organic farming as a promising alternative to enhance plant growth and development. Maggot frass, a byproduct of the larval digestion process, is rich in essential nutrients such as nitrogen, phosphorus, potassium, and contains beneficial microorganisms for the soil. This study employs a literature review method. Literature sources were obtained from the Google Scholar database using keywords such as "maggot frass", "kasgot", "Black Soldier Fly", and "Hermetia illucens". The articles obtained were then analyzed to gather secondary data. The aim of this research is to explore the potential utilization of maggot frass from BSF larvae in enhancing plant growth and development in the context of organic farming. Research on the utilization of maggot frass has shown significant potential in improving soil fertility and increasing crop productivity. Furthermore, the use of BSF larvae in organic waste management can also significantly reduce waste volume while creating valuable resources for agriculture. By integrating the utilization of maggot frass into organic farming practices, it is hoped that a more sustainable and environmentally friendly agricultural system can be created in the future.
Co-Authors Aulia, Annisa Maliza, Rita Muhammad Idris Resti Rahayu Rismayani, Dessy Zozy Aneloi Noli