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PENETAPAN NILAI SUN PROTECTION FACTOR EKSTRAK KULIT COKLAT (THEOBROMA CACAO L.) DALAM BASIS LOTION DAN EVALUASI KARAKTERISTIK SEDIAAN Damopolii, Billy Pratama; Kusumaningtyas, Febrianika Ayu; Akune, Nadia Ayuwanda S
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 3 (2025): DESEMBER 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i3.50402

Abstract

Paparan sinar UV oleh matahari dapat menimbulkan kerusakan pada kulit seperti eritema, dan penuaan dini. Kulit coklat (Theobroma cacao L.) merupakan tanaman yang memiliki kadar senyawa flavonoid yang tinggi dengan aktivitas dapat menangkal sinar Ultraviolet Radiation (UVR). Penelitian ini bertujuan untuk menetapkan nilai Sun Protection Factor dalam basis lotion dengan perbandingan konsentrasi ekstrak FI(1%), F2(3%) dan F3(5%) serta evaluasi karakteristik yang meliputi uji organoleptik, uji pH, uji homogenitas, uji daya sebar, dan uji daya lekat. Hasil penelitian menunjukkan penambahan ekstrak dengan perbandingan konsentrasi berpengaruh dalam uji homogenitas, daya sebar, daya lekat, dan nilai SPF tetapi tidak pada uji daya pH. Dapat disimpulkan sediaan lotion dengan nilai SPF dan memenuhi syarat sediaan lotion terdapat dapa F1 Dengan konsentrasi 1%.
Antibacterial Activity Test of Ethanol Extract and Fraction of Carrot Leaf (Daucus Carota L.) Against Staphylococcus Aureus Akune, Nadia Ayuwanda S; Rahmawati, Ismi; Sulaiman, Saifullah
Jurnal Multidisiplin Madani Vol. 4 No. 3 (2024): March, 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/mudima.v4i3.8604

Abstract

Staphylococcus aureus is one of the bacteria that cause acne and can cause skin and organ damage because bacteria can defeat the body's defences. Carrot leaf extract has antibacterial power or inhibitory activity against S. aureus. This study aims to determine the inhibition value and antibacterial activity of ethanol extract and n-hexane fraction of carrot leaves. The research method consists of extraction using 96% ethanol and fractionation using water, ethyl acetate, and n-hexane. The antibacterial activity of carrot leaf extracts and fractions was carried out using the pitting method as well as the use of gentamicin positive control and DMSO negative control. The results showed that 96% ethanol extract of carrot leaves with a concentration of 30% had inhibition against S. aureus bacteria with a value of 7.8 mm or weak inhibitory activity, and the ethyl acetate fraction of carrot leaves with a concentration of 20% had inhibition against S. aureus bacteria with a value of 11.27 mm or strong inhibitory activity. Therefore, ethyl acetate fraction of carrot leaves have inhibition against S. aureus bacteria with strong inhibitory activity compared to other test solutions and is equivalent to gentamicin positive control